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NiHowdy > Drug Classes > Keratolytics

Browse Medications by Drug Class: Keratolytics

Author

Written by Amar Lunagaria

Pharm.D • NiHowdy Founder

Reviewed By

Reviewed by James Wong

Pharm.D • NiHowdy Founder

Published Jan 15, 2025

Fact checked Fact checked

What are Keratolytics?

Keratolytics are a class of medications or topical agents that help soften, loosen, and remove the outer layer of the skin, primarily the stratum corneum. These treatments work by breaking down keratin, a protein that causes skin cells to stick together, facilitating the shedding of thickened or rough skin. Keratolytics are commonly used for conditions like acne, psoriasis, warts, and other dermatological disorders characterized by hyperkeratosis or excessive skin buildup. A unique feature of keratolytics is their ability to enhance skin renewal while improving the effectiveness of other topical therapies. NiHowdy ensures affordable access to these skin-care solutions, helping patients achieve healthier and clearer skin.

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List of drugs in Keratolytics

Drug NameMore InformationNiHowdy Prices & Bitcoin Rebate
AcNesicAcNesic InformationAcNesic Pricing
Ammonium LactateAmmonium Lactate InformationAmmonium Lactate Pricing
Bensal HPBensal HP InformationBensal HP Pricing
CantharidinCantharidin InformationCantharidin Pricing
CEM-UreaCEM-Urea InformationCEM-Urea Pricing
CerovelCerovel InformationCerovel Pricing
CondyloxCondylox InformationCondylox Pricing
DermacinRx UreaDermacinRx Urea InformationDermacinRx Urea Pricing
GeametdrayGeametdray InformationGeametdray Pricing
GordofilmGordofilm InformationGordofilm Pricing
Grafco Silver Nit ApplicatorGrafco Silver Nit Applicator InformationGrafco Silver Nit Applicator Pricing
Hydro 40Hydro 40 InformationHydro 40 Pricing
KeralacKeralac InformationKeralac Pricing
KeralytKeralyt InformationKeralyt Pricing
Lactic AcidLactic Acid InformationLactic Acid Pricing
Podocon-25Podocon-25 InformationPodocon-25 Pricing
PodofiloxPodofilox InformationPodofilox Pricing
ProtexaProtexa InformationProtexa Pricing
SalexSalex InformationSalex Pricing
Salicylic AcidSalicylic Acid InformationSalicylic Acid Pricing
Salicylic Acid ERSalicylic Acid ER InformationSalicylic Acid ER Pricing
Salicylic Acid Wart RemoverSalicylic Acid Wart Remover InformationSalicylic Acid Wart Remover Pricing
SalimezSalimez InformationSalimez Pricing
Salimez ForteSalimez Forte InformationSalimez Forte Pricing
SalvaxSalvax InformationSalvax Pricing
UltraSal-ERUltraSal-ER InformationUltraSal-ER Pricing
Umecta MousseUmecta Mousse InformationUmecta Mousse Pricing
UramaxinUramaxin InformationUramaxin Pricing
UreaUrea InformationUrea Pricing
Urea HydratingUrea Hydrating InformationUrea Hydrating Pricing
Urea NailUrea Nail InformationUrea Nail Pricing
UredebUredeb InformationUredeb Pricing
Uremez-40Uremez-40 InformationUremez-40 Pricing
UresolUresol InformationUresol Pricing
UtopicUtopic InformationUtopic Pricing
VirasalVirasal InformationVirasal Pricing
XalixXalix InformationXalix Pricing
XureaXurea InformationXurea Pricing

Brief history about Keratolytics?

Keratolytics have been used for centuries, with salicylic acid, a natural compound derived from willow bark, being one of the oldest remedies for skin disorders. Modern keratolytics, such as urea, lactic acid, and benzoyl peroxide, were developed in the 20th century to treat a wide range of dermatological conditions. These agents have revolutionized skin care by providing effective, targeted therapies for managing chronic skin conditions. NiHowdy simplifies access to these trusted treatments, ensuring affordability for individuals seeking healthier skin.

How do Keratolytics work?

Keratolytics work by breaking down keratin, a key structural protein in the skin's outer layer. By softening and dissolving this protein, keratolytics help loosen dead skin cells and promote their removal. This action reduces thickened, rough skin and clears clogged pores, which are common in acne and other conditions. For example, salicylic acid penetrates the skin and dissolves the bonds between dead cells, making it effective for exfoliating and unclogging pores. When used in combination with other treatments, keratolytics improve skin texture and enhance the absorption of active ingredients. NiHowdy ensures patients can access these advanced skin-care solutions affordably and conveniently.

What are Keratolytics used to treat?

Acne

Keratolytics like salicylic acid and benzoyl peroxide are widely used to treat acne. By exfoliating dead skin cells and unclogging pores, these agents reduce inflammation, prevent new breakouts, and improve skin texture. They are particularly effective for mild to moderate acne and are often included in over-the-counter and prescription skin-care products.

Psoriasis

In psoriasis, keratolytics help manage the excessive skin cell buildup that leads to scaling and plaques. Urea and salicylic acid are commonly used to soften and remove thickened skin, allowing other topical treatments, such as corticosteroids or vitamin D analogs, to penetrate more effectively.

Warts

Salicylic acid is a first-line treatment for warts, working to dissolve the keratin layer and gradually remove the wart tissue. Keratolytics are often used in combination with freezing therapies to enhance treatment outcomes and speed up recovery.

Seborrheic Dermatitis

Keratolytics are used to treat seborrheic dermatitis by reducing scaling and flaking, particularly on the scalp. Agents like salicylic acid and sulfur are included in medicated shampoos to manage symptoms and restore skin health.

Who should consider Keratolytics medications?

Adults

Adults with dermatological conditions such as acne, psoriasis, or warts benefit from keratolytics as part of their skin-care regimen. These treatments provide effective exfoliation, improve the penetration of other topical agents, and enhance overall skin health. Keratolytics are particularly useful for adults managing chronic skin conditions or seeking smoother, clearer skin.

Children

Keratolytics can be used safely in children for conditions like warts, mild acne, or psoriasis under medical supervision. Pediatric formulations ensure appropriate dosing and minimize irritation. Parents appreciate the convenience and effectiveness of these treatments in addressing common skin concerns in younger populations.

Seniors

Seniors with thickened or rough skin, such as corns, calluses, or hyperkeratosis, benefit from keratolytics for maintaining skin health and comfort. These agents are particularly useful for addressing age-related changes in skin texture and reducing discomfort from pressure points. Careful monitoring ensures safety and efficacy in this population.

Are Keratolytics safe?

Keratolytics are generally safe and well-tolerated when used as directed. Common side effects include mild irritation, redness, or peeling, particularly at the beginning of treatment. Rare but serious risks include allergic reactions or excessive dryness, especially with improper use or over-application. Patients should follow usage instructions carefully and consult their healthcare provider if irritation persists or worsens.

Can I take Keratolytics during pregnancy?

Some keratolytics, like salicylic acid, can be used during pregnancy in low concentrations under medical supervision. However, high concentrations or extensive use should be avoided. Pregnant individuals should consult their healthcare provider to determine the safest options for managing skin conditions during pregnancy.

Are Keratolytics safe to take while lactating?

Keratolytics are generally safe to use while breastfeeding when applied topically and in low concentrations. However, it is important to avoid application to the breast area to prevent accidental ingestion by the infant. Patients should discuss their treatment plan with their healthcare provider.

Are Keratolytics controlled substances?

Keratolytics are not classified as controlled substances. They are available over-the-counter in low concentrations and by prescription for higher strengths. Proper use under guidance ensures safe and effective results.

Side effects of Keratolytics?

Keratolytics are generally well-tolerated, but they may cause side effects, particularly with higher concentrations or prolonged use. Common side effects include mild redness, peeling, or dryness, which are typically temporary and improve with continued use or moisturizer application. Less common side effects include skin irritation or sensitivity, particularly in individuals with sensitive skin or when applied excessively. Adjusting the frequency or concentration of the product can help mitigate these effects. Rare but serious side effects include severe allergic reactions or chemical burns, especially with improper use. Patients should discontinue use and seek immediate medical attention if they experience symptoms such as swelling, severe redness, or blistering. Regular communication with a healthcare provider ensures safe and effective use of keratolytics, minimizing side effects and optimizing outcomes for patients managing skin conditions.

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Cost considerations and insurance coverage for Keratolytics

The cost of keratolytics varies depending on the specific medication and formulation. Over-the-counter options like salicylic acid are affordable, while prescription-strength keratolytics may be more expensive. Most insurance plans cover prescription keratolytics for dermatological conditions. NiHowdy offers discounts, rebates, and Bitcoin rewards to ensure these treatments remain accessible and cost-effective.

How do I get rebates on Keratolytics?

NiHowdy's Bitcoin rebate program for keratolytic prescriptions provides patients with a unique opportunity to save on healthcare costs while earning potential financial growth. This innovative approach makes managing skin conditions both affordable and rewarding, improving access to effective treatments while building long-term value.

Therapeutic Classes linked to Keratolytics

Medical Conditions treated by Keratolytics