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Uresol
Uresol is a topical medication that contains urea, used to treat dry, rough, and scaly skin conditions. It works by softening and moisturizing the skin, making it helpful for conditions like eczema, psoriasis, keratosis pilaris, and ichthyosis. Uresol is a keratolytic agent, meaning it helps to break down hardened, dead skin cells, promoting smoother, softer skin.
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Frequently Asked Questions
How long does it take for Uresol to improve skin condition?
You may start noticing improvements in skin hydration and texture within a few days to a week of regular use. Full benefits, particularly for thickened skin or nails, may take longer.
Can Uresol be used on the face?
Yes, Uresol can be used on the face, but it is recommended to use lower concentrations (10% or 20%) to avoid irritation. Avoid the eye area and mucous membranes.
Is Uresol safe for children?
Uresol is generally safe for use in children, but you should consult a healthcare provider before using it on children younger than 2 years old or on sensitive areas of the skin.
Can Uresol be used to treat cracked heels?
Yes, Uresol is effective for treating cracked heels and thickened skin. It helps soften and hydrate the skin, making it easier to remove calluses and promote healing.
Should I apply Uresol before or after other moisturizers?
Apply Uresol first to soften the skin, then follow with an emollient moisturizer to lock in hydration and enhance the moisturizing effects.
Comprehensive Drug Guide
How Does Uresol Work?
Urea, the active ingredient in Uresol, increases moisture in the skin by softening and loosening the outer layer of the skin, known as the stratum corneum. This keratolytic action allows for the shedding of dead skin cells while also drawing moisture into the skin, making it more supple and hydrated. Urea also helps break down thickened areas of skin, making it useful for conditions involving rough or scaly skin.
Common Dosages
- 10% urea for mild dry skin
- 20% urea for moderate dry skin or mild scaling
- 40% urea for severe scaling or thickened skin conditions
Typical Dosing
- Apply a thin layer of Uresol to the affected area once or twice daily or as directed by your healthcare provider.
- Massage the cream or lotion into the skin until it is fully absorbed.
Typical Dosing
FDA Approved Indications
- Dry skin (xerosis)
- Psoriasis
- Eczema
- Keratosis pilaris
- Ichthyosis (scaly skin conditions)
- Calluses and thickened nails
Who Shouldn't Take Uresol?
- Known hypersensitivity or allergic reactions to urea or any of the ingredients in the formulation.
- Severely irritated or broken skin, as urea may cause further irritation.
Advice From The Pharmacist
- For best results, apply Uresol after bathing when the skin is still damp, as this will help lock in moisture.
- If treating thickened areas, such as calluses or thickened nails, soak the area in warm water before applying Uresol to help enhance the treatment.
- Avoid using Uresol on open wounds or broken skin unless directed by your healthcare provider.
- Store Uresol at room temperature and keep it out of direct sunlight and moisture.
Side Effects of Uresol
Common Side Effects
- Mild skin irritation (redness, stinging, or burning)
- Temporary itching
- Dryness or peeling
Uncommon/Severe Side Effects
- Severe skin irritation or allergic reactions (rash, swelling, difficulty breathing)
- Chemical burns, particularly with higher concentrations of urea or prolonged use.
Risks and Warnings of Uresol
- Skin Irritation: Urea, especially in higher concentrations, can cause skin irritation in some individuals. Discontinue use if severe irritation or allergic reactions occur.
- Avoid Open Wounds: Do not apply Uresol to open wounds or severely broken skin, as it may exacerbate irritation or delay healing.
- Caution in Sensitive Skin: Use lower concentrations (10% or 20%) on sensitive areas like the face, and consult your healthcare provider before using higher concentrations.
Interactions with Uresol
Common Drug Interactions
- There are no significant drug interactions associated with topical use of Uresol. However, avoid combining it with other topical treatments unless advised by your healthcare provider, as this can increase the risk of irritation.
Alternatives to Uresol
- AmLactin: A lactic acid-based moisturizer used for treating dry, rough, and scaly skin.
- Carmol: Another urea-containing product available in various concentrations for similar skin conditions.
- Topical salicylic acid: Often used for exfoliation and treatment of thickened skin or keratosis pilaris.
- Prescription-strength moisturizers: Containing ceramides or other emollients, used for severe cases of dry skin or eczema.
