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Keralac

Keralac is a brand name for urea, a topical medication commonly used to treat various skin conditions, particularly those characterized by dryness, scaling, and thickening of the skin. It works as a keratolytic agent, helping to soften and remove dry, scaly skin, making it effective for conditions such as psoriasis, eczema, and ichthyosis. Keralac promotes hydration and improves the overall texture of the skin.

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Frequently Asked Questions

How long does it take for Keralac to work?

Keralac typically begins to improve the condition of dry skin within a few days to a week of regular use, but individual responses may vary.

Can I use Keralac on my face?

Yes, Keralac can be used on the face, but it is advisable to start with a lower concentration and monitor for any irritation.

What should I do if I miss a dose of Keralac?

If you miss a dose, apply it as soon as you remember. If it is almost time for your next application, skip the missed dose and continue with your regular schedule. Do not double up on doses.

Is Keralac safe during pregnancy?

Keralac is generally considered safe for topical use during pregnancy, but it is recommended to consult your healthcare provider before using any medication.

Can I use other skin products while using Keralac?

Yes, but it is advisable to wait until Keralac has absorbed fully before applying other products to avoid reducing its effectiveness or causing irritation.

Comprehensive Drug Guide

How Does Keralac Work?

Urea acts by increasing the water content of the stratum corneum (the outermost layer of the skin) and breaking down the bonds between skin cells. This process promotes the shedding of dead skin cells and softens the thickened skin. By enhancing hydration, Keralac helps to restore the natural barrier function of the skin, making it smoother and more elastic.

Common Dosages

10%, 20%, 30%, and 40% urea creams or lotions.

The dosage and frequency of application depend on the severity of the skin condition and the specific formulation used.

Typical Dosing

For dry skin conditions: Apply a thin layer of Keralac to the affected area once or twice daily, or as directed by a healthcare provider. The frequency can be adjusted based on individual response and tolerability.

Typical Dosing

FDA Approved Indications

Relief of dry skin conditions (e.g., psoriasis, eczema, ichthyosis)
Hydration of the skin to improve skin texture

Who Shouldn't Take Keralac?

Known hypersensitivity or allergy to urea or any components of the formulation.
Open wounds or broken skin unless directed by a healthcare provider.

Advice From The Pharmacist

Apply Keralac as directed: Follow your healthcare provider's instructions regarding dosage and frequency. Ensure the skin is clean and dry before application.
Monitor for skin irritation: If you experience excessive redness, burning, or irritation, reduce the frequency of application or discontinue use and consult your healthcare provider.
Avoid contact with eyes and mucous membranes: If contact occurs, rinse thoroughly with water.
Store Keralac at room temperature, away from heat and moisture, and keep it out of reach of children.

Side Effects of Keralac

Common Side Effects

Skin irritation
Burning sensation at the application site
Redness or itching
Dryness or flaking of the skin

Uncommon/Severe Side Effects

Severe allergic reactions (e.g., rash, swelling, difficulty breathing)

Risks and Warnings of Keralac

Skin Reactions: Prolonged use of urea can lead to skin irritation in some individuals. It is important to monitor for any adverse reactions and adjust the usage accordingly.
Sensitivity to Sunlight: Urea can increase sensitivity to sunlight. Patients should apply sunscreen or protective clothing when exposed to sunlight.
Not for Infected Skin: Keralac should not be applied to infected or inflamed skin unless directed by a healthcare provider.

Interactions with Keralac

Common Drug Interactions

Keralac has minimal known drug interactions since it is primarily used topically. However, patients should inform their healthcare provider about all medications they are taking, including topical products, to avoid potential interactions.

Alternatives to Keralac

Salicylic acid: Another keratolytic agent used to treat similar skin conditions.
Lactic acid: A moisturizing agent that also has exfoliating properties.
Topical corticosteroids: Used for inflammatory skin conditions to reduce redness and itching.