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Urea Hydrating

Urea Hydrating products are topical formulations used to treat dry, rough, and scaly skin conditions, such as eczema, psoriasis, keratosis pilaris, and ichthyosis. Urea is a keratolytic and moisturizing agent that softens and hydrates the skin by breaking down rough skin cells and increasing water content in the skin. Urea hydrating products are available in various strengths, with higher concentrations used for more severe skin conditions.



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Frequently Asked Questions

How long does it take for Urea Hydrating products to work?
Open FAQClose FAQ

Improvement can typically be seen within a few days to a week of regular use, but more severe conditions may require several weeks of consistent treatment to show significant improvement.

Can I use Urea Hydrating products on my face?
Open FAQClose FAQ

Yes, but lower concentrations (10% or 20%) are generally preferred for facial use to avoid irritation. Higher concentrations may be too strong for delicate facial skin.

Is Urea Hydrating safe for children?
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Urea can be used in children for dry skin or other conditions, but it is important to use the appropriate concentration and follow your healthcare provider’s recommendations.

Can Urea Hydrating products be used for nail conditions?
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Yes, urea is often used to soften and thin thickened or damaged nails, making them easier to trim or treat. Concentrations of 30% to 40% are typically used for this purpose.

Can I use Urea Hydrating with other moisturizers?
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Yes, urea can be used with other moisturizers. It is often beneficial to apply urea first to exfoliate and soften the skin, followed by an emollient to lock in moisture.

Comprehensive Drug Guide

How Does Urea Hydrating Work?

Urea works by softening the keratin in the outer layer of the skin, which helps to exfoliate dead skin cells and smoothen rough or hardened areas. It also acts as a humectant, drawing moisture into the skin and helping to retain it, which makes the skin more hydrated and flexible. This dual action helps to reduce dryness, flaking, and scaling associated with various skin conditions.



Common Dosages

  • 10% urea (available OTC) for mild dry skin.
  • 20% urea for more moderate dryness or scaling.
  • 30% to 40% urea (prescription strength) for severe dryness, calluses, or thickened skin.

Typical Dosing

  • Apply a thin layer of the urea cream, lotion, or gel to the affected areas once or twice daily, or as directed by a healthcare provider.
  • Gently massage the product into the skin until fully absorbed.
  • For best results, apply after bathing when the skin is still damp to help lock in moisture.


Typical Dosing

FDA Approved Indications

  • Dry skin (xerosis)
  • Eczema
  • Psoriasis
  • Keratosis pilaris
  • Ichthyosis
  • Calluses and corns
  • Thickened or damaged nails (higher concentrations)


Who Shouldn't Take Urea Hydrating?

  • Known hypersensitivity to urea or any of the other ingredients in the formulation.
  • Open wounds or severely irritated skin, unless specifically directed by a healthcare provider.


Advice From The Pharmacist

  • Apply urea hydrating products exactly as directed and avoid overuse, particularly with higher concentrations, as they may cause irritation or stinging.
  • Be careful to avoid contact with the eyes or mucous membranes (inside the mouth, nose, etc.).
  • For best results, apply after bathing or showering to help lock in moisture.
  • If you experience excessive irritation or discomfort, stop using the product and consult your healthcare provider.


Side Effects of Urea Hydrating

Common Side Effects

  • Mild stinging or burning at the application site
  • Redness or irritation
  • Dryness or peeling


Uncommon/Severe Side Effects

  • Severe allergic reactions (rash, itching, swelling, difficulty breathing)
  • Increased sensitivity to sunlight in some formulations


Risks and Warnings of Urea Hydrating

  • Skin Irritation: Higher concentrations of urea (20% and above) can cause irritation, particularly on sensitive or broken skin. If irritation persists or worsens, discontinue use and consult a healthcare provider.
  • Avoid Open Wounds: Do not apply urea to open wounds or severely irritated skin unless specifically directed by a healthcare provider, as it may worsen irritation.


Interactions with Urea Hydrating

Common Drug Interactions

  • There are no known significant drug interactions with Urea Hydrating products when used topically. However, always inform your healthcare provider of any other medications or treatments you are using, especially other topical products, to avoid potential skin irritation.



Alternatives to Urea Hydrating

  • Lactic Acid (Amlactin): Another keratolytic agent that helps to soften and exfoliate dry, rough skin.
  • Salicylic Acid: Used for softening rough skin and removing warts, calluses, and scaling.
  • Glycolic Acid: A chemical exfoliant that helps to smooth and hydrate the skin.
  • Prescription-strength moisturizers containing ceramides for severe dry skin or eczema.