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Cantharidin

Cantharidin is a naturally occurring substance derived from certain types of beetles, known as blister beetles. It is mainly used for treating certain skin conditions, including molluscum contagiosum and warts. Potential side effects primarily involve skin reactions, like blistering, burning, and itching.

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Frequently Asked Questions

Can I apply Cantharidin at home?
Open FAQClose FAQ

No, cantharidin should only be applied by a healthcare provider in a clinical setting.

Can I wash the treated area after Cantharidin?
Open FAQClose FAQ

After applying cantharidin, you should keep the treated area dry for at least four to six hours.

What happens if I accidentally swallow Cantharidin?
Open FAQClose FAQ

Cantharidin is a powerful vesicant and is toxic if swallowed. Seek immediate medical help if it's accidentally ingested.

Comprehensive Drug Guide

How Does Cantharidin Work?

Cantharidin is an antimitotic agent that induces acantholysis, resulting in blister formation which aids in the removal of skin growth.

What is Cantharidin Used For?

FDA indications: Cantharidin is primarily used for the topical treatment of warts and molluscum contagiosum.

Offlabel uses: Some practitioners also use it for other skin conditions like calluses and certain types of skin tags.

Common Dosages

Topical solution: 0.7%

Typical Dosing

FDA Approved Indications

  • For warts & molluscum contagiosum: Only applied by a healthcare provider in a clinic

Who Shouldn't Take Cantharidin?

  • People who have allergies to any ingredient in cantharidin.
  • Especially near the eyes, mouth, or genitals.
  • Also, not suitable for moles or birthmarks.

Advice From The Pharmacist

  • Only a healthcare provider should apply Cantharidin.
  • Make sure to not get it in the eyes or mouth.
  • Keep the treated area dry for 24 hours.
  • Don't use a bandage or any occlusive dressings unless directed by your doctor.
  • Discontinue use and call your healthcare provider if severe blistering, bleeding, or pain occurs.

Side Effects of Cantharidin

Common Side Effects

  • You might have mild to moderate itching, burning, or tingling at the site of application.
  • You can experience blistering at the site of application, this is part of the treatment process.

Uncommon/Severe Side Effects

  • Uncommon, Rare, or Severe side effects:
  • Severe skin reactions or blistering.
  • If the blisters become too painful, get medical help.

Risks and Warnings of Cantharidin

  • Use only as directed by a healthcare provider.
  • Avoid contact with the eyes, nose, mouth, and other mucous membranes.
  • In case of accidental ingestion, seek emergency medical help.
  • Discontinue use and inform your healthcare provider if severe skin reactions occur.

Interactions with Cantharidin

Common Drug Interactions

  • Presently unknown.

Alternatives to Cantharidin

  • Salicylic Acid
  • Imiquimod
  • Trichloroacetic Acid
  • Cryotherapy
  • Podophyllotoxin
  • Laser Therapy
  • Curettage or Cautery