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Uredeb
Uredeb is a topical urea cream used to treat dry, rough, or scaly skin conditions such as eczema, psoriasis, keratosis pilaris, and ichthyosis. Urea is a keratolytic and moisturizing agent that softens the outer layer of the skin, promoting the shedding of dead skin cells while helping to hydrate and smoothen the skin.
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Frequently Asked Questions
How long does it take for Uredeb to work?
You may start to notice improvement in your skin’s texture and hydration within a few days to a week of regular use. Full benefits may take longer, especially for thickened skin or nails.
Can Uredeb be used on the face?
Yes, Uredeb can be used on the face, but lower concentrations (10% or 20%) are recommended to avoid irritation. Avoid applying the cream near the eyes or mouth.
Is Uredeb safe for long-term use?
Yes, Uredeb is generally safe for long-term use, especially for chronic skin conditions like eczema or psoriasis. However, prolonged use of higher concentrations should be monitored by a healthcare provider.
Can Uredeb be used on cracked heels?
Yes, Uredeb is effective for treating cracked heels. It softens the hardened skin, allowing for easier removal and promoting healing.
Can Uredeb be used with other moisturizers?
Yes, Uredeb can be used alongside other moisturizers. Apply Uredeb first to soften the skin, and then follow with an emollient or moisturizing cream to lock in moisture.
Comprehensive Drug Guide
How Does Uredeb Work?
Urea, the active ingredient in Uredeb, works by increasing the skin’s moisture content and softening keratin, a protein in the skin. This action promotes the shedding of dead skin cells and enhances skin hydration, improving the texture and smoothness of rough or scaly skin. Urea also helps to break down hardened, thickened skin, making it beneficial for conditions like keratosis pilaris and ichthyosis.
Common Dosages
- 10% urea cream/lotion for mild to moderate dry skin.
- 20% urea cream/lotion for more severe dry skin or scaling.
- 40% urea cream/lotion for thickened skin, nails, or stubborn conditions like psoriasis or ichthyosis.
Typical Dosing
- Apply a thin layer of Uredeb to the affected area(s) once or twice daily or as directed by your healthcare provider.
- Gently massage the cream or lotion into the skin until it is fully absorbed.
Typical Dosing
FDA Approved Indications
- Dry skin (xerosis).
- Psoriasis.
- Eczema.
- Keratosis pilaris.
- Ichthyosis (scaly skin conditions).
- Thickened nails or calluses.
Who Shouldn't Take Uredeb?
- Known hypersensitivity to urea or any component of the formulation.
- Severely irritated or open skin, unless recommended by a healthcare provider, as urea can cause irritation on broken skin.
Advice From The Pharmacist
- Apply Uredeb after bathing or showering, when the skin is still slightly damp, to enhance the absorption and effectiveness of the cream.
- For best results, use Uredeb regularly, and do not apply it to healthy skin that does not require treatment.
- If using Uredeb on thickened nails or calluses, soften the area by soaking it in warm water before applying the cream.
- Store Uredeb at room temperature and keep it away from excessive moisture or heat.
Side Effects of Uredeb
Common Side Effects
- Mild skin irritation (redness, stinging, or burning)
- Temporary itching or dryness
- Peeling or flaking of the skin
Uncommon/Severe Side Effects
- Severe allergic reactions (rash, swelling, difficulty breathing)
- Severe skin irritation or chemical burns, particularly with prolonged or overuse.
Risks and Warnings of Uredeb
- Skin Irritation: Urea, particularly in higher concentrations (e.g., 40%), can cause skin irritation, especially on sensitive or damaged skin. If irritation becomes severe, discontinue use and consult your healthcare provider.
- Avoid Open Wounds: Uredeb should not be applied to open wounds, cuts, or severely inflamed skin, as it may worsen irritation.
- Use Caution in Children: Consult a healthcare provider before using Uredeb on children, especially younger than 2 years of age, as urea can be too strong for delicate skin.
Interactions with Uredeb
Common Drug Interactions
- There are no significant drug interactions associated with topical use of Uredeb. However, avoid applying other topical treatments to the same area without consulting your healthcare provider, as this can increase the risk of irritation.
Alternatives to Uredeb
- AmLactin: A lactic acid-based lotion that helps to exfoliate and hydrate dry, rough skin.
- Carmol: A urea-containing cream available in various concentrations for the treatment of dry skin conditions.
- Salicylic acid-based creams: Used for exfoliation in cases of thickened skin or keratosis pilaris.
- Prescription-strength moisturizers: May contain ceramides or other ingredients for severe dry skin or eczema.
