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Podocon-25

Podocon-25 (podosin or podophyllum resin) is a topical medication used for the treatment of genital warts (condylomata acuminata) caused by the human papillomavirus (HPV). It is derived from the root of the podophyllum plant and acts as an antimitotic agent, inhibiting cell division and leading to the destruction of wart tissue.



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Frequently Asked Questions

How quickly does Podocon-25 start to work?
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Patients may begin to notice improvements in the appearance of warts within 1 to 2 weeks of consistent application, though complete resolution may take longer.

Can I use Podocon-25 while pregnant or breastfeeding?
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Consult your healthcare provider before using Podocon-25 if you are pregnant, planning to become pregnant, or breastfeeding to assess any potential risks.

Are there any specific dietary restrictions while using Podocon-25?
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There are no specific dietary restrictions associated with the use of Podocon-25.

What should I do if I miss a dose of Podocon-25?
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If you miss a dose, apply it as soon as you remember. If it’s close to the time for your next scheduled dose, skip the missed dose and continue with your regular schedule. Do not double up on doses.

Is Podocon-25 safe for long-term use?
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Podocon-25 is typically intended for short-term use to treat genital warts. Long-term use should be monitored by a healthcare provider to assess effectiveness and any potential side effects. Regular follow-ups are important to ensure optimal management of warts.

Comprehensive Drug Guide

How Does Podocon-25 Work?

  • Inhibiting mitosis: It disrupts the normal cell cycle, preventing the proliferation of the wart tissue and causing local necrosis.
  • Promoting local tissue destruction: By affecting the rapidly dividing cells in the wart, it helps to eliminate the wart over time.


Common Dosages

  • Topical solution: Usually concentrated as 25% podophyllum resin in a suitable solvent.

Typical Dosing

  • The recommended dosing is to apply a thin layer of Podocon-25 directly to the affected area, typically once weekly. The specific frequency and duration of treatment may vary based on the healthcare provider’s instructions.


Typical Dosing

FDA Approved Indications

  • Treatment of external genital warts caused by HPV.


Who Shouldn't Take Podocon-25?

  • Known hypersensitivity to podophyllum resin or any components of the formulation.
  • Warts located inside the vagina or on the cervix, as these areas may require different treatment approaches.


Advice From The Pharmacist

  • Instruct patients to apply Podocon-25 carefully, avoiding contact with healthy skin to minimize irritation.
  • Advise patients to wash their hands thoroughly after applying the solution to prevent unintentional contact with other areas of the body.
  • Discuss potential side effects, including local irritation or allergic reactions, and encourage patients to report any severe or unusual symptoms.


Side Effects of Podocon-25

Common Side Effects

  • Local irritation or burning
  • Redness or swelling at the application site
  • Dryness or crusting of the treated area


Uncommon/Severe Side Effects

  • Severe allergic reactions (such as rash, itching, or difficulty breathing).


Risks and Warnings of Podocon-25

  • Skin Reactions: Monitor for local skin reactions, especially in sensitive areas. If excessive irritation occurs, patients should discontinue use and consult their healthcare provider.
  • Pregnancy and Breastfeeding: The safety of Podocon-25 during pregnancy and breastfeeding has not been fully established; consult a healthcare provider before use in these situations.


Interactions with Podocon-25

Common Drug Interactions

  • Other Topical Products: Patients should inform their healthcare provider about all topical medications they are using, as combining products can increase the risk of irritation or adverse effects.


Alternatives to Podocon-25

  • Other Treatments for Genital Warts: Alternatives may include other topical agents such as imiquimod, trichloroacetic acid (TCA), or cryotherapy, depending on individual patient needs and the extent of the condition.