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Uramaxin
Uramaxin is a topical urea cream used to treat dry, rough, and thickened skin conditions such as eczema, psoriasis, keratosis pilaris, and ichthyosis. Urea is a keratolytic and moisturizing agent that softens and hydrates the skin by helping to remove dead skin cells and improve the skin’s moisture retention. It is commonly prescribed for individuals with skin conditions that cause scaling, roughness, and dryness.
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Frequently Asked Questions
How long does it take for Uramaxin to work?
You may start to notice improvements in your skin’s texture and moisture within a few days to a week of regular use. However, full benefits may take several weeks, particularly for conditions involving thickened skin or nails.
Can Uramaxin be used on the face?
Yes, Uramaxin can be used on the face, but lower concentrations (such as 20%) are recommended to avoid irritation. Avoid contact with the eyes, mouth, and other sensitive areas.
Is Uramaxin safe for long-term use?
Yes, Uramaxin is generally safe for long-term use, especially for chronic skin conditions like psoriasis or keratosis pilaris. However, prolonged use of high concentrations should be monitored to avoid irritation.
Can Uramaxin be used on cracked heels?
Yes, Uramaxin is effective for treating cracked heels. It softens the hardened skin, allowing for easier removal and promoting healing.
Can Uramaxin be used with other moisturizers?
Yes, Uramaxin can be used with other moisturizers. It is often beneficial to apply Uramaxin first to exfoliate and soften the skin, followed by an emollient to lock in moisture.
Comprehensive Drug Guide
How Does Uramaxin Work?
Urea, the active ingredient in Uramaxin, works by breaking down keratin, a protein that forms part of the skin structure. This action helps to exfoliate dead skin cells, smoothen rough or hardened areas, and draw moisture into the skin, making it softer and more hydrated. Urea also enhances the skin’s ability to hold water, preventing further dryness and thickening of the skin.
Common Dosages
- 20% urea cream for mild to moderate dry skin.
- 40% urea cream for more severe cases, including thickened skin or nails.
Typical Dosing
- Apply a thin layer of Uramaxin to the affected area(s) once or twice daily, or as directed by your healthcare provider.
- Massage the cream into the skin until it is fully absorbed. For best results, apply after bathing when the skin is still slightly damp to help lock in moisture.
Typical Dosing
FDA Approved Indications
- Dry skin (xerosis)
- Psoriasis
- Eczema
- Keratosis pilaris
- Ichthyosis
- Thickened skin or nails
Who Shouldn't Take Uramaxin?
- Known hypersensitivity to urea or any of the ingredients in the formulation.
- Open wounds or severely irritated skin, unless directed by a healthcare provider, as urea can cause further irritation in these cases.
Advice From The Pharmacist
- Use Uramaxin exactly as prescribed or according to package directions. Apply only to the affected areas and avoid using it on healthy skin to prevent irritation.
- For the best results, apply after bathing when the skin is still damp. This helps the urea penetrate more effectively and increases moisture retention.
- Store the product at room temperature and keep it away from excessive heat or moisture.
- If using Uramaxin on thickened nails, soften the nails by soaking them in warm water before applying the cream.
Side Effects of Uramaxin
Common Side Effects
- Mild skin irritation (redness, stinging, or burning)
- Dryness or peeling
- Temporary itching at the application site
Uncommon/Severe Side Effects
- Severe allergic reactions (rash, swelling, difficulty breathing)
- Severe skin irritation or chemical burns with prolonged use or overuse
Risks and Warnings of Uramaxin
- Skin Irritation: Urea, particularly in higher concentrations (e.g., 40%), can cause skin irritation, especially on sensitive or damaged skin. If irritation becomes severe, discontinue use and consult your healthcare provider.
- Avoid Open Wounds: Uramaxin should not be applied to open wounds, cuts, or severely inflamed areas, as it may worsen irritation or delay healing.
- Use Caution in Children: Consult with a healthcare provider before using Uramaxin on children, particularly those under 2 years of age.
Interactions with Uramaxin
Common Drug Interactions
- There are no significant drug interactions associated with topical use of Uramaxin. However, avoid applying other topical products on the same area unless recommended by a healthcare provider, as this can increase the risk of skin irritation.
Alternatives to Uramaxin
- AmLactin: A lactic acid-based lotion that helps to exfoliate and hydrate dry, rough skin.
- Carmol: Another urea-containing cream available in various strengths, used for similar skin conditions.
- Salicylic acid-based creams: These are used for exfoliation in cases of thickened skin or keratosis pilaris.
- Prescription-strength moisturizers: These may include ceramides for severe dry skin or eczema.
