NiHowdy > Drug Classes > Antimalarials

Browse Medications by Drug Class: Antimalarials

Written by Amar Lunagaria

Pharm.D • NiHowdy Founder

Reviewed by James Wong

Pharm.D • NiHowdy Founder

Published Jan 15, 2025

Fact checked

What are Antimalarials?

Antimalarials are a class of medications used to prevent and treat malaria, a life-threatening disease caused by Plasmodium parasites transmitted through mosquito bites. These medications work by targeting various stages of the parasite's lifecycle, either in the liver or the bloodstream. Antimalarials are also used for other conditions, such as autoimmune diseases like lupus and rheumatoid arthritis, due to their anti-inflammatory properties. A unique characteristic of antimalarials is their dual role in both treating malaria and preventing its recurrence. NiHowdy ensures affordable access to these critical medications, helping patients protect against and recover from malaria effectively.

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List of drugs in Antimalarials

Drug Name	More Information	NiHowdy Prices & Bitcoin Rebate

Alinia	Alinia Information	Alinia Pricing
Arakoda	Arakoda Information	Arakoda Pricing
Atovaquone	Atovaquone Information	Atovaquone Pricing
Atovaquone-Proguanil HCl	Atovaquone-Proguanil HCl Information	Atovaquone-Proguanil HCl Pricing
Chloroquine Phosphate	Chloroquine Phosphate Information	Chloroquine Phosphate Pricing
Coartem	Coartem Information	Coartem Pricing
Daraprim	Daraprim Information	Daraprim Pricing
Hydroxychloroquine Sulfate	Hydroxychloroquine Sulfate Information	Hydroxychloroquine Sulfate Pricing
Krintafel	Krintafel Information	Krintafel Pricing
Lampit	Lampit Information	Lampit Pricing
Malarone	Malarone Information	Malarone Pricing
Mefloquine HCl	Mefloquine HCl Information	Mefloquine HCl Pricing
Mepron	Mepron Information	Mepron Pricing
Nitazoxanide	Nitazoxanide Information	Nitazoxanide Pricing
Plaquenil	Plaquenil Information	Plaquenil Pricing
Primaquine Phosphate	Primaquine Phosphate Information	Primaquine Phosphate Pricing
Qualaquin	Qualaquin Information	Qualaquin Pricing
quiNINE Sulfate	quiNINE Sulfate Information	quiNINE Sulfate Pricing

Brief history about Antimalarials?

The history of antimalarials dates back to the 17th century, when quinine, derived from the bark of the cinchona tree, was used to treat malaria. In the 20th century, synthetic antimalarials like chloroquine and mefloquine were developed, revolutionizing malaria treatment. Advances in drug discovery led to the creation of artemisinin-based combination therapies (ACTs), which are now the gold standard for treating malaria. NiHowdy simplifies access to these essential medications, ensuring affordability for patients at risk of or recovering from malaria.

How do Antimalarials work?

Antimalarials work by disrupting the lifecycle of the Plasmodium parasite at various stages. For example, chloroquine inhibits parasite metabolism in red blood cells, while artemisinin-based therapies target rapidly dividing parasites. Other antimalarials, such as primaquine, target dormant liver-stage parasites to prevent relapses. NiHowdy provides affordable access to antimalarials, ensuring patients receive effective treatment tailored to their specific needs.

What are Antimalarials used to treat?

Malaria Treatment

Antimalarials like artemisinin-based combination therapies (e.g., artemether-lumefantrine) are used to treat acute malaria caused by Plasmodium falciparum and Plasmodium vivax.

Malaria Prevention

Medications like doxycycline, mefloquine, and atovaquone-proguanil are used as prophylactic treatments for travelers visiting malaria-endemic regions.

Complicated Malaria

For severe or cerebral malaria, intravenous antimalarials like artesunate are used in hospital settings to quickly eliminate parasites.

Autoimmune Diseases

Antimalarials such as hydroxychloroquine are used to manage autoimmune diseases like lupus and rheumatoid arthritis due to their immunomodulatory effects.

Who should consider Antimalarials medications?

Adults

Antimalarials are commonly prescribed for adults traveling to or living in malaria-endemic areas, as well as those with autoimmune conditions like lupus. NiHowdy ensures adults can access these treatments affordably and conveniently.

Children

In pediatric cases, antimalarials are used to treat or prevent malaria. Doses are carefully adjusted based on weight and age to ensure safety and efficacy. NiHowdy supports families with cost-effective solutions and reliable resources for managing pediatric malaria prevention and treatment.

Seniors

Seniors traveling to malaria-endemic regions or those managing autoimmune conditions benefit significantly from antimalarials. Careful monitoring is required to adjust dosing and manage potential side effects. NiHowdy simplifies access to antimalarials for seniors, offering affordable options tailored to their unique needs.

Are Antimalarials safe?

Antimalarials are generally safe when prescribed and monitored appropriately. Common side effects include nausea, dizziness, and gastrointestinal discomfort. Rare but serious risks include vision changes (e.g., with long-term hydroxychloroquine use) and neuropsychiatric symptoms (e.g., with mefloquine). Patients should inform their healthcare provider about any pre-existing conditions or medication history. NiHowdy provides safe and affordable access to antimalarials, supported by expert guidance to manage these risks responsibly.

Can I take Antimalarials during pregnancy?

Some antimalarials, like chloroquine and mefloquine, are considered safe during pregnancy for preventing or treating malaria. However, certain medications, such as doxycycline, are not recommended during pregnancy. Patients should consult their healthcare provider for personalized advice. NiHowdy provides cost-effective access to expert guidance and alternative treatments for pregnant patients.

Are Antimalarials safe to take while lactating?

Many antimalarials, such as chloroquine and hydroxychloroquine, are considered safe during lactation, with minimal transfer into breast milk. Patients should consult their healthcare provider for specific recommendations based on the medication and treatment goals. NiHowdy ensures affordable access to trusted information and safe treatment options for breastfeeding parents.

Are Antimalarials controlled substances?

Antimalarials are not classified as controlled substances but require a prescription to ensure proper use and monitoring. NiHowdy simplifies the prescription process, ensuring patients receive these critical medications affordably and responsibly.

Side effects of Antimalarials?

Common side effects of antimalarials include nausea, dizziness, headache, and gastrointestinal discomfort. Rare but serious risks include vision problems, neuropsychiatric effects, and allergic reactions. Patients experiencing severe side effects should consult their healthcare provider immediately. NiHowdy helps patients manage these risks with expert-backed support and affordable care options.

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Cost considerations and insurance coverage for Antimalarials

The cost of antimalarials varies depending on the specific medication and formulation (e.g., oral or intravenous). Generic options like chloroquine and hydroxychloroquine are generally affordable, and many insurance plans cover these medications for approved indications. NiHowdy offers discounts, rebates, and Bitcoin rewards to ensure these treatments remain accessible and cost-effective.

How do I get rebates on Antimalarials?

NiHowdy's Bitcoin rebate program for antimalarial prescriptions offers patients a unique opportunity to save on healthcare costs while earning potential financial growth. This innovative approach makes managing malaria and autoimmune conditions both affordable and rewarding, improving access to critical care while building long-term value.