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Hydroxychloroquine Sulfate
Hydroxychloroquine Sulfate is an antimalarial and immunosuppressive medication primarily used to prevent and treat malaria. It is also prescribed for autoimmune conditions such as rheumatoid arthritis and lupus erythematosus. The drug helps reduce inflammation and modulates the immune system's activity, providing relief from symptoms associated with these conditions.
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Frequently Asked Questions
How quickly does Hydroxychloroquine Sulfate work for malaria?
It is usually effective within a few days for treating malaria, but the full course of treatment is necessary to ensure complete eradication of the parasite.
Can I take Hydroxychloroquine Sulfate while pregnant?
Consult your healthcare provider, as it may be prescribed during pregnancy for certain conditions, but benefits and risks must be evaluated.
What should I do if I miss a dose?
If you miss a dose, take it as soon as you remember. If it's close to the time for your next dose, skip the missed dose and continue with your regular schedule. Do not double up.
Are there any specific storage instructions for Hydroxychloroquine Sulfate?
Store at room temperature, away from moisture and light. Keep out of reach of children.
Is Hydroxychloroquine Sulfate safe for long-term use?
Long-term use requires regular monitoring by a healthcare provider to manage risks, including potential retinal toxicity.
Comprehensive Drug Guide
How Does Hydroxychloroquine Sulfate Work?
Hydroxychloroquine works by interfering with the communication between cells in the immune system and by inhibiting the function of certain immune cells. It also disrupts the growth of the malaria parasite within red blood cells. This dual action helps reduce inflammation in autoimmune diseases and treats malaria.
What is Hydroxychloroquine Sulfate Used For?
Hydroxychloroquine is approved to treat and prevent malaria, and to manage symptoms of lupus and rheumatoid arthritis.
Common Dosages
- Tablets: Common strengths include 200 mg and 400 mg.
Typical Dosing
The typical dosing for Hydroxychloroquine Sulfate is:
- For Malaria: 400 mg orally once a week for prophylaxis, starting 1-2 weeks before travel and continuing for 4 weeks after leaving the area.
- For Rheumatoid Arthritis or Lupus: The usual starting dose is 400 to 600 mg daily, adjusted based on clinical response.
Typical Dosing
FDA Approved Indications
- Prophylaxis and treatment of malaria.
- Management of rheumatoid arthritis.
- Treatment of systemic lupus erythematosus.
Who Shouldn't Take Hydroxychloroquine Sulfate?
- Hypersensitivity: Known hypersensitivity to hydroxychloroquine or any components of the formulation.
- Retinal Disorders: Pre-existing retinal damage or visual field defects due to previous use of 4-aminoquinoline compounds.
Advice From The Pharmacist
- How to Use: Take hydroxychloroquine with food or milk to help reduce gastrointestinal side effects.
- Monitor for Side Effects: Patients should be monitored for any visual changes or signs of adverse reactions, especially with long-term use.
- Regular Eye Exams: Routine eye examinations are recommended during treatment to monitor for potential retinal toxicity.
Side Effects of Hydroxychloroquine Sulfate
Common Side Effects
- Nausea or vomiting
- Diarrhea
- Abdominal cramps
- Headaches
Uncommon/Severe Side Effects
- Retinopathy: Potential damage to the retina leading to vision changes.
- Severe allergic reactions: Such as rash, itching, or difficulty breathing.
Risks and Warnings of Hydroxychloroquine Sulfate
- Risk of Retinal Toxicity: Long-term use increases the risk of retinal damage; dose adjustments may be necessary.
- Caution in Certain Conditions: Use with caution in patients with a history of liver disease or psoriasis.
Interactions with Hydroxychloroquine Sulfate
Common Drug Interactions
- Drug Interactions: Hydroxychloroquine may interact with other medications, including certain antimalarials and digoxin, potentially increasing toxicity. Always inform your healthcare provider about all medications you are taking.
Alternatives to Hydroxychloroquine Sulfate
- Other Antimalarials: Such as chloroquine for malaria treatment.
- Non-steroidal Anti-inflammatory Drugs (NSAIDs): For symptomatic relief in rheumatoid arthritis.
