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Cortef
Hydrocortisone is a type of medication known as a steroid or corticosteroid, similar to the natural hormone produced by your adrenal glands. It's used for an array of conditions because it reduces inflammation and suppresses the immune system, thus helping with conditions like arthritis, lupus, psoriasis, allergies, asthma, and skin conditions. Some common side effects include increased appetite, mood changes, and trouble sleeping, but your doctor will usually ensure the benefits outweigh these issues.
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Frequently Asked Questions
Can I take hydrocortisone if I have diabetes?
Yes, but be aware that it may increase blood sugar levels. If you're diabetic, monitor your sugar levels closely while on this medication.
Does hydrocortisone make you gain weight?
It can, as some folks notice increased appetite and subsequent weight gain.
What should I do if I miss a dose of hydrocortisone?
Stay calm if it's near your next dose, skip the missed one. If not, take it as soon as you remember. But remember, never double the doses!
Can I stop taking hydrocortisone once my symptoms are gone?
Don't discontinue the medication abruptly; doing so could be harmful. Your doctor will usually gradually decrease your dosage to give your body time to adjust.
Will hydrocortisone affect my mood?
It can cause mood swings in some people. If you start feeling unusually sad or anxious, communicate with your doctor.
Comprehensive Drug Guide
How Does Cortef Work?
Hydrocortisone is a synthetic corticosteroid that imitates the functions of endogenous hormones. It suppresses our body's immune response and moderates inflammation, ultimately altering our body's responses to various medical conditions.
What is Cortef Used For?
FDA indications: Hydrocortisone is used to treat conditions such as severe skin allergies, arthritis, asthma, certain skin conditions, hormonal disorders, and more.
Off-label uses: It has been used for off-label treatment of multiple sclerosis during relapse and for its immunosuppressive properties in organ transplantation.
Common Dosages
Tablets: 5mg, 10mg, 20mg
Creams and ointments: 1% to 2.5%
Typical Dosing
FDA Approved Indications
- For FDA-approved indications: The dosage will depend on the medical condition and patient tolerance. A general daily dosage can range between 10 to 240mg per day in divided doses.
Off-Label Uses
- For off-label uses: Depends on the disease being treated and will be determined by the healthcare provider.
Who Shouldn't Take Cortef?
- Have fungal infections anywhere in the body.
- Have a history of tuberculosis.
- Have certain eye conditions.
- Suffer from stomach ulcers or a past history of them.
- Have liver or kidney conditions.
- Have heart conditions, like heart failure or a recent heart attack.
- Have high blood pressure.
- Are pregnant, planning to get pregnant, or breastfeeding.
- Have mental health conditions like depression or psychosis.
- Have osteoporosis.
- Have diabetes or a family history of diabetes.
Advice From The Pharmacist
- Take it easy on the salt. Hydrocortisone can retain extra water and salt in your body, leading to swelling.
- Strive to eat balanced meals. Hydrocortisone can increase your appetite and may cause weight gain.
- Taking this medication with food helps avoid upsetting your stomach.
- Hydrocortisone taken in the morning will help align it with your body's natural rhythms and reduce the chances of insomnia.
- Don't abruptly stop taking hydrocortisone. Your doctor will likely taper you off to avoid withdrawal symptoms.
- Stay vigilant about bone health. Hydrocortisone can thin your bones over time. Consider incorporating calcium and vitamin D supplements into your routine.
- If you notice erratic mood swings or feel unusually anxious, let your doctor know. Hydrocortisone can affect your mood.
- Got a fever or signs of infection? Inform your doctor because Hydrocortisone can mask these symptoms.
- Remember to take good care of yourself! Regular doctor's appointments and check-ups are key.
Side Effects of Cortef
Common Side Effects
- Weight gain due to increased hunger, mood swings, sleep issues, 'moon face'.
- Difficulty fighting infections.
- Thinner or easily bruised skin.
Uncommon/Severe Side Effects
- Rare side effects:
- Cataracts or glaucoma.
- High blood sugar levels, which could lead to diabetes.
- Severe side effects:
- Unusual fatigue, rapid weight gain, or swelling in the ankles or feet.
- Seeing blood in your stools or vomit warrants immediate medical attention.
- Should you experience symptoms like fever, cough, difficulty breathing, or severe nausea or vomiting, these are serious and need medical help.
- Signs of a severe allergic reaction like rash, itching or swelling of the face/tongue/throat, severe dizziness, or trouble breathing necessitate immediate medical attention.
Risks and Warnings of Cortef
- Hydrocortisone can lead to challenging side effects in certain situations; its application is discouraged if you have active fungal infections, a history of tuberculosis, or certain types of eye infections unless otherwise specified by your doctor.
- Proceed with caution if you have a history of stomach ulcers or liver or kidney diseases; Hydrocortisone can potentially worsen these issues.
- Be mindful that if you have had heart issues such as recent heart attacks or heart failure; this drug can compound these problems. You should consult your doctor if you have a history of these conditions.
- Blood pressure issues? Hydrocortisone can increase blood pressure; hence those suffering from hypertension need to exercise caution.
- Pregnancy and breastfeeding could pose concerns. The effects of Hydrocortisone on infants aren?t fully known, so consult a healthcare provider before using it if you're pregnant, planning to be, or breastfeeding.
- To those struggling with mental health issues or mood disorders like depression or psychosis, tread carefully. Hydrocortisone could potentially worsen these conditions.
- If you have diabetes or your family has a history of the disease, inform your doctor because Hydrocortisone can escalate blood glucose levels.
- Lastly, be aware that Hydrocortisone can increase the risk of osteoporosis. Regular bone density tests and precautions are recommended if you have this condition.
Interactions with Cortef
Common Drug Interactions
- Warfarin
- Phenobarbital
- Phenytoin
- Rifampin
- Insulin
- Diuretics (such as furosemide)
- Ketoconazole
- NSAIDs (like ibuprofen, naproxen)
- Antidepressants (like fluoxetine, sertraline)
Alternatives to Cortef
- Prednisone
- Methylprednisolone
- Dexamethasone
- Cortisone
- Triamcinolone
- Betamethasone
- Budesonide
