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methylPREDNISolone

Methylprednisolone is a type of medication that falls under the category of steroids or corticosteroids. These potent drugs are employed to curb inflammation, and thus, they find use in tackling a host of afflictions such as allergies, arthritis, problems relating to the skin and blood, eye conditions, and lung diseases like asthma. A few common side effects are sleep issues, mood swings, or an increase in appetite, but your doctor's shrewd assessment will ensure that the upsides counter these potential downers.

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Frequently Asked Questions

Can I just stop taking Methylprednisolone after my symptoms are gone?
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No, you should always consult with your healthcare provider before making any changes to your medication regimen.

Can I take Methylprednisolone if I have diabetes?
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Yes, but bear in mind it can elevate your sugar levels. You'll have to keep a closer eye on your glucose levels while on this medication.

Does Methylprednisolone make you gain weight?
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Yes, it can. Many people experience an increase in appetite and may see a gain in weight.

I missed a dose of Methylprednisolone, what should I do?
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Don't panic. If it's nearly time for your next dose, skip the missed one. Otherwise, take it as soon as you remember. But remember, doubling up on doses is a big nono!

Comprehensive Drug Guide

How Does methylPREDNISolone Work?

Methylprednisolone is a synthetic corticosteroid that mimics the actions of hormones made within the body. It mitigates the body's immune response, reduces inflammation, and modifies the body's physiological response to various diseases.

What is methylPREDNISolone Used For?

FDA indications: Methylprednisolone is used to treat a variety of conditions, including allergic disorders, skin conditions, ulcerative colitis, arthritis, lupus, psoriasis, or breathing disorders.

Offlabel uses: It's also been used for offlabel treatment of multiple sclerosis, acute gouty arthritis, and gastrointestinal conditions like Crohn?s disease. Its immunosuppressive properties have also proven beneficial in organ transplantation.

Common Dosages

Tablets: 2mg, 4mg, 8mg, 16mg, 32mg.

Injection: 40mg/ml, 125mg/2ml, 500mg/8ml, 1000mg/16ml

Typical Dosing

FDA Approved Indications

  • For FDAapproved indications:
  • Allergy and inflammation: 4 to 48mg per day.
  • Skin diseases: 4 to 48mg per day.
  • Breathing problems: 4 to 48mg per day.

Off-Label Uses

  • For offlabel uses:
  • Multiple sclerosis: 200mg per day for one week.
  • Acute gouty arthritis: 120mg as a onetime dose.
  • Organ transplantation: 10 to 80mg per day, used along with other immunosuppressive drugs.
  • Crohn?s disease: Dose varies according to the severity of the condition and your doctor?s instructions.

Who Shouldn't Take methylPREDNISolone?

  • Those with fungal infections.
  • Those with a history of tuberculosis.
  • Those with specific eye infections.
  • Those with stomach ulcers or a history of stomach ulcers.
  • Those suffering from liver or kidney disease.
  • Those with heart issues like heart failure or who have recently had a heart attack.
  • Those with high blood pressure.
  • Those planning to become pregnant, pregnant, or breastfeeding (it's unknown whether methylprednisolone can harm the baby).
  • Those having mental health issues like depression or psychosis.
  • Those with osteoporosis.
  • Those with diabetes or a family history of diabetes.

Advice From The Pharmacist

  • Keep an eye on your salt intake as methylprednisolone can cause your body to retain more water and salt, which can result in swelling.
  • Try to maintain a nutritious, balanced diet as methylprednisolone may increase your appetite leading to weight gain.
  • Take this medication with meals to avoid any gastrointestinal discomfort.
  • To prevent sleep disturbances, your doctor might advise you to take it in the morning.
  • Don't abruptly stop taking methylprednisolone your doctor will guide you on decreasing your dose to prevent withdrawal symptoms.
  • Pay attention to your bones. Methylprednisolone can weaken your bones over time. Consider supplements that contain calcium and vitamin D.
  • Talk to your doctor if you're feeling unusually down or anxious. Methylprednisolone can impact your mood.
  • If you have symptoms of an infection like a fever, report it to your doctor. This medication can mask some signs of infection.
  • Regular checkups are vital when taking this medication.

Side Effects of methylPREDNISolone

Common Side Effects

  • Increased appetite resulting in weight gain.
  • Mood swings, feeling anxious, or having trouble sleeping.
  • Puffy or round face referred to as 'moon face'.
  • A surge in susceptibility to infections.
  • Thinning skin, bruising easily, or slow healing of wounds.

Uncommon/Severe Side Effects

  • Rare side effects:
  • Cataracts or glaucoma.
  • High blood sugar, which could lead to diabetes.
  • Severe side effects:
  • Unusual fatigue, rapid weight gain, swelling in the ankles or feet.
  • Appearance of blood in stool or vomit seek immediate medical assistance.
  • Fever, cough, shortness of breath, severe nausea or vomiting contact your doctor straight away.
  • Signs of a serious allergic reaction like rashes, itching/swelling of the face/tongue/throat, severe dizziness, or troubled breathing need immediate medical attention.

Risks and Warnings of methylPREDNISolone

  • The benefits of Methylprednisolone are manifold, but it's not for everyone. It can cause harmful side effects in certain situations and should be avoided if you have an active fungal infection, a prior history of tuberculosis, or certain eye infections (unless expressly recommended by your healthcare provider).
  • Use caution if you have a history of stomach ulcers or diseases of the liver or kidney ? Methylprednisolone could potentially exacerbate these issues.
  • Heart issues such as recent heart attacks or heart failure can worsen under the influence of Methylprednisolone. If you have a history of these conditions, you should consult with your doctor.
  • Have trouble with high blood pressure? Methylprednisolone might raise your blood pressure, so proceed carefully if you have hypertension.
  • If you are pregnant, planning to become pregnant, or breastfeeding, consult with your healthcare provider about safety concerns. The effects of Methylprednisolone on the unborn baby are not known.
  • For those with mental health troubles or mood disorders such as depression or psychosis, tread carefully. Methylprednisolone could potentially trigger or exacerbate these conditions.
  • If you or your family have a history of diabetes, be sure to inform your doctor, as Methylprednisolone can increase blood glucose levels.
  • Lastly, this medication could increase the risk of osteoporosis. So if you already have this boneweakening disease, getting periodical bone density tests and taking necessary precautions are vital.

Interactions with methylPREDNISolone

Common Drug Interactions

  • Blood thinners like Warfarin.
  • Barbiturates like Phenobarbital.
  • Seizure medications like Phenytoin.
  • Antibiotics like Rifampin.
  • Diabetes medications including Insulin.
  • Diuretics like Furosemide.
  • Antifungal medications like Ketoconazole.
  • NSAIDs like Ibuprofen and Naproxen.
  • Antidepressants like Fluoxetine and Sertraline.

Alternatives to methylPREDNISolone

  • Prednisone
  • Hydrocortisone
  • Dexamethasone
  • Cortisone
  • Triamcinolone
  • Betamethasone
  • Budesonide