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Amoxicillin
Amoxicillin is a widely used antibiotic belonging to the penicillin class. It is commonly prescribed to treat various bacterial infections, including ear infections, throat infections, urinary tract infections, and skin infections. Amoxicillin works by inhibiting the synthesis of bacterial cell walls, leading to the destruction of the bacteria. It is often considered a first-line treatment for many infections due to its broad spectrum of activity and safety profile.
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Frequently Asked Questions
Can I drink alcohol while I'm on Amoxicillin?
While it's not recommended to drink alcohol when you're feeling unwell, it's generally okay to have a drink or two while taking Amoxicillin. But remember, alcohol can dehydrate you and slow your recovery, so it's best to take it easy.
Can I take Amoxicillin if I'm allergic to penicillin?
Consult your primary care provider before anything. If you're allergic to penicillin, you could have an allergic reaction to Amoxicillin as well.
I have leftover Amoxicillin from a previous illness. Can I use it now?
No, you shouldn't use leftover antibiotics. They might not be the right kind or dose for your current illness. Always consult with your healthcare provider before taking any medication.
Is Amoxicillin safe if I'm pregnant or breastfeeding a child?
Generally, Amoxicillin is considered safe for use during pregnancy and while breastfeeding. But every situation is different, so it's always a good idea to check with your primary care provider.
Is it okay to stop taking Amoxicillin once I feel better?
No, it's important to take the full course of the antibiotic as prescribed, even if you start feeling better. Stopping early can lead to the infection returning or bacteria becoming resistant to the antibiotic.
What should I do if I miss a dose of my Amoxicillin?
If you forget a dose, take it as soon as you remember. If it's nearly time for your next dose, skip the missed one. Never take two doses at once to make up for a missed one.
Comprehensive Drug Guide
How Does Amoxicillin Work?
Amoxicillin works by inhibiting the enzyme transpeptidase, which is involved in the synthesis of bacterial cell walls. By disrupting the formation of the cell wall, amoxicillin causes the bacteria to weaken and eventually burst, leading to the elimination of the infection. It is effective against a wide range of gram-positive and some gram-negative bacteria.
What is Amoxicillin Used For?
Amoxicillin is approved by the FDA for the treatment of infections caused by susceptible bacteria, such as ear infections, strep throat, pneumonia, skin infections, and urinary tract infections.
Offlabel uses include conditions such as prevention of bacterial endocarditis, treatment of Helicobacter pylori as part of combination therapy, and Lyme disease.
Common Dosages
Amoxicillin is most commonly prescribed in dosages between 200500mg, with the suspension (liquid) form being between 125250mg
Typical Dosing
FDA Approved Indications
- Ear, Nose, Throat infections: 500 mg every 12 hours or 250 mg every 8 hours for mild/moderate infections and 875 mg every 12 hours or 500 mg every 8 hours for severe infections.
- Lower Respiratory Tract infections: 875 mg every 12 hours or 500 mg every 8 hours.
- Skin/Skin Structure infections: 500 mg every 12 hours or 250 mg every 8 hours for mild/moderate infections and 875 mg every 12 hours for severe infections.
- Urinary Tract infections: 500 mg every 12 hours or 250 mg every 8 hours for mild/moderate infections and 875 mg every 12 hours for severe infections.
Off-Label Uses
- Bacterial Endocarditis Prophylaxis: 2 g orally, 30 to 60 minutes before procedure.
- H. Pylori Treatment (as part of combination therapy): 1 g twice daily for 1014 days.
- Lyme Disease: 500 mg three times a day for 14 to 21 days.
Pediatric Dosing
- Ear, Nose, or Throat Infection: Normally, it's about 20 to 50 mg/kg/day (divided into two doses a day) for mild to moderate infections, and can go up to 80 to 90 mg/kg/day (split into two doses) for severe infections. We're talking milligrams of medicine for every kilogram of a kid's body weight.
- Urinary tract infection or Skin infection: Usually, it's about 20 to 50 mg/kg/day (divided into two doses a day) for the milder stuff, and can go up to 80 to 90 mg/kg/day (split into two doses) for the tougher bugs.
Who Shouldn't Take Amoxicillin?
- Avoid or consult your primary care provider about taking Amoxicilllin if you have Mononucleosis (Mono) as this drug can cause a rash which might be mistakenly identified as an allergic reaction, or severe kidney disease.
Advice From The Pharmacist
- Don't stop taking Amoxicillin just because you feel better. It's important to finish the full course to make sure all the bacteria are killed off.
- If you miss a dose, take it as soon as you remember unless it's nearly time for your next dose. Never take two doses at once to make up for a forgotten one.
- Amoxicillin can be taken with or without food. If it upsets your stomach, try taking it with a meal.
- If you're allergic to penicillin, you shouldn't take Amoxicillin. Let your doctor know about any allergies you have.
- While it's generally okay to have a drink while taking Amoxicillin, remember that alcohol can dehydrate you and may slow down your recovery.
- Don't use leftover Amoxicillin from a previous illness. It might not be the right medication or dose for your current condition.
Side Effects of Amoxicillin
Common Side Effects
- Upset stomach or diarrhea
- Skin rash
Uncommon/Severe Side Effects
- Allergic reaction: This could be serious trouble breathing, a super swollen face or throat, or a rash all over your body. If this occurs you need to go to the nearest hospital.
- Severe stomach pain: If there is intense pain in your stomach, especially if the pain is on the lower right side (where your appendix is), get medical help right away.
- Bloody or watery diarrhea
Risks and Warnings of Amoxicillin
- Diarrhea: Amoxicillin can sometimes mess with your gut, causing diarrhea. Now, if you're seeing mucus or blood in your stool, or you're getting stomach cramps or a fever, that could mean something more serious is going on, like a bacterial infection in your intestines. .
- Liver problems: Although it's pretty rare, Amoxicillin can cause some issues with your liver. If you notice your skin or the whites of your eyes turning yellow, or your pee is darker than usual, that could be a sign your liver is not doing well.
- Let your doctor if you experience any side effects with your prescription.
Interactions with Amoxicillin
Common Drug Interactions
- Methotrexate
- Allopurinol
- Warfarin
- Probenecid
- Live Typhoid Vaccine
- Tetracyclines
- Chloroquine
- BCG Vaccine
Alternatives to Amoxicillin
- Here are some alternative FDAapproved medications that can be considered as alternatives to Amoxicillin:
- Penicillin VK (Penicillin V potassium): Another penicillin antibiotic commonly used to treat various bacterial infections.
- Cephalexin (Keflex): A cephalosporin antibiotic effective against a wide range of bacterial infections.
- Azithromycin (Zithromax): A macrolide antibiotic used to treat respiratory, skin, and sexually transmitted infections.
- Clindamycin (Cleocin): An antibiotic used for treating serious skin and soft tissue infections, dental infections, and other bacterial infections.
- Ciprofloxacin (Cipro): A fluoroquinolone antibiotic that treats a variety of bacterial infections, including respiratory, urinary tract, and gastrointestinal infections.
- Levofloxacin (Levaquin): Another fluoroquinolone antibiotic used to treat respiratory, urinary tract, and skin infections, as well as certain types of pneumonia.
