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levoFLOXacin
Levofloxacin is an antibiotic that belongs to a group of drugs known as fluoroquinolones. It's used to treat a variety of bacterial infections, such as skin infections, sinus infections, respiratory tract infections, urinary tract infections, and more. Some common side effects include nausea, diarrhea, and headache, but your doctor will weigh these possible side effects against the benefits of treating your infection.
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Frequently Asked Questions
Can I have a glass of wine while on Levofloxacin?
It's best to avoid alcohol while on this medication. It can increase your risk of developing side effects.
Can I just stop taking Levofloxacin after my symptoms are gone?
It's crucial to finish your prescribed course of levofloxacin, even if you're feeling better before it's finished, as stopping early can lead to bacterial resistance.
Can I take Levofloxacin if I have kidney disease?
Yes, but your doctor may need to adjust your dose accordingly.
Can I take Levofloxacin with food?
For best results, take levofloxacin on an empty stomach, either 1 hour before meals or two hours after.
Does Levofloxacin make you sunburn more easily?
Yes, levofloxacin can make your skin more sensitive to sunlight. It's best to avoid sun exposure and use sunscreen while on this medication.
I missed a dose of Levofloxacin, what should I do?
If you remember within 2 hours of your missed dose, take the missed dose. If more time has passed, just take your next dose at your regular time. Never take two doses together to "make up"" for a missed one."
Will Levofloxacin affect my mood?
Levofloxacin can cause some people to feel nervous or anxious. If you experience mood changes, talk to your doctor.
Comprehensive Drug Guide
How Does levoFLOXacin Work?
: Levofloxacin works by inhibiting the enzymes topoisomerase IV and DNAgyrase in bacterial cells, which are required for bacterial DNA replication, transcription, repair, and recombination. This inhibits bacterial growth.
What is levoFLOXacin Used For?
FDA indications: Levofloxacin is used to treat a variety of conditions caused by bacterial infections, including sinus infections, bronchitis, pneumonia, skin infections, urinary tract infections, and infections of the prostate gland in men.
Offlabel uses: It's also been used for the offlabel treatment of infectious diarrhea and tuberculosis.
Common Dosages
Tablets: 250mg, 500mg, 750mg
Oral solution: 25mg/mL
Typical Dosing
FDA Approved Indications
- Sinus infections: 500mg once a day for 10 to 14 days.
- Bronchitis: 500mg once a day for 7 days.
- Pneumonia: 500mg once a day for 7 to 14 days.
- Skin infections: 750mg once a day for 7 to 14 days.
- Urinary tract infections: 250mg once a day for 3 days.
- Prostate infections: 500mg once a day for 28 days.
Off-Label Uses
- Infectious diarrhea: 500mg once a day for 10 days.
- Tuberculosis: 500mg to 1000mg once a day for at least 6 months along with other antituberculosis drugs.
Who Shouldn't Take levoFLOXacin?
- Have a history of allergic reactions to the fluoroquinolone antibiotic class.
- Have a history of tendinitis or tendon rupture after taking a fluoroquinolone antibiotic.
- Have the myasthenia gravis condition.
- Have a history of dangerous electrolyte imbalance.
- Have a history of abnormal heart rhythm.
- Have a history of liver disease.
- Are pregnant or planning to become pregnant.
- Have a history of kidney disease.
- Have a history of epilepsy or other seizure disorders.
Advice From The Pharmacist
- Take levofloxacin with a full glass of water. Drink plenty of extra water while you're taking levofloxacin to keep your kidneys working properly.
- Avoid taking antacids, calcium, zinc, iron, or vitamin supplements at least 2 hours before or after taking levofloxacin. These can bind with levofloxacin and prevent your body from fully absorbing the drug.
- Avoid excessive sunlight or tanning beds. Levofloxacin can make you sunburn more easily. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.
- Take levofloxacin on an empty stomach, at least 1 hour before or 2 hours after a meal.
- Do not take levofloxacin with dairy products such as milk or yogurt, or with calciumfortified juice.
- Avoid caffeine while you're on this medication, it could lead to jitters or increased heart rate.
- Levofloxacin can cause you to have false results with certain medical tests. Tell any healthcare provider who treats you that you are using it.
- If you have symptoms of fever, rash, or painful skin, seek medical help immediately.
Side Effects of levoFLOXacin
Common Side Effects
- Nausea, vomiting, or diarrhea.
- Headache, dizziness, or trouble sleeping.
- Possible sun sensitivity, so take care when you're outdoors.
Uncommon/Severe Side Effects
- Uncommon side effects:
- Feeling lightheaded or faint.
- Rapid heartbeat or chest pain.
- Seizures or tremors.
- Low blood sugar, which can make you shake or sweat.
- Rare side effects:
- Trouble breathing or swallowing.
- Severe skin rash or other skin problems like red, swollen, blistered, or peeling skin.
- Severe side effects:
- Mood or behavior changes, such as feeling more nervous or anxious.
- Unusual tiredness or weakness.
- If you notice any other side effects, be sure to chat with your healthcare provider.
Risks and Warnings of levoFLOXacin
- Levofloxacin should not be prescribed if you have a history of allergic reactions to any fluoroquinolone antibiotics.
- Levofloxacin has been linked to a risk of rupture in tendons, particularly in patients who are older than 60 or that take corticosteroid medication.
- Levofloxacin can cause seizures in some patients, so avoid taking it if you have a history of seizures, epilepsy, or any other health condition that causes seizures.
- Levofloxacin can prolong QT interval, leading to an abnormal heart rhythm which can be serious and potentially fatal.
- If you are pregnant, planning to become pregnant, or are nursing, it is essential to consult your healthcare provider. Levofloxacin poses risks to the fetus and its safety has not been established in nursing mothers.
- Levofloxacin has been shown to raise the risk of experiencing peripheral neuropathy?a condition affecting the nerves in the peripheral nervous system, leading to weakness, numbness, and pain.
Interactions with levoFLOXacin
Common Drug Interactions
- Nonsteroidal antiinflammatory drugs (NSAIDs)
- Class IA and III antiarrhythmics.
- Live bacterial vaccines
- Drugs that affect the kidney
Alternatives to levoFLOXacin
- Ciprofloxacin
- Moxifloxacin
- Norfloxacin
- Ofloxacin
- Gemifloxacin
