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Azithromycin
Azithromycin is an antibiotic medication that's used to treat a variety of bacterial infections including bronchitis, pneumonia, sexually transmitted diseases, and infections of the ears, lungs, skin, and throat. Known for its broad-spectrum antimicrobial activity, azithromycin is quite effective at combating a wide range of bacteria.
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Frequently Asked Questions
I missed a dose of azithromycin, what should I do?
If it's not too close to your next dose, take the missed one. But if your next dose is soon, skip the missed one. Never take two to make up for it.
How long does it take for azithromycin to start working?
Usually, you should start feeling better after a couple of days. But don't stop taking it until you finish the full course, even if you feel better.
Is it okay to take azithromycin if I'm pregnant or breastfeeding?
If you're pregnant, planning to be, or breastfeeding, you gotta tell your doc. They'll weigh the pros and cons for you.
Does azithromycin affect birth control pills?
Generally, azithromycin doesn't interfere with birth control. However, if you get sick with vomiting or diarrhea, your birth control pills might not work as well.
Can I drink alcohol while taking azithromycin?
While it's not a hard no, it's probably better to skip the booze. Alcohol can increase the chance of side effects and slow down how fast you recover.
Comprehensive Drug Guide
How Does Azithromycin Work?
Azithromycin acts by binding to the 50S subunit of the bacterial ribosome, thus inhibiting protein synthesis and preventing the growth of susceptible bacteria.
What is Azithromycin Used For?
Azithromycin is used widely to treat many different types of bacterial infections such as bronchitis, pneumonia, sexually transmitted diseases, and ear, lung, skin, and throat infections.
Common Dosages
- Tablets/Capsules: 250mg, 500mg, 600mg
- Oral suspension: 100mg/5mL, 200mg/5mL
- Intravenous powder for solution: 500mg
Typical Dosing
FDA Approved Indications
- Respiratory infections, skin infections: 500mg on the first day, then 250mg once daily for 4 days.
- For off-label uses:
- Pertussis (whooping cough): 500mg on the first day, followed by 250mg daily for 4 days.
- Lyme disease: 500mg daily for 7 to 10 days.
Off-Label Uses
Azithromycin has been used off-label to treat Traveler’s diarrhea, Lyme disease, pertussis (whooping cough), and to prevent heart infection in people having dental or other procedures.
Pediatric Dosing
Pediatric dosing of azithromycin depends on the type and severity of the infection as well as the child's weight. Your child's doctor will provide specific dosing instructions.
Who Shouldn't Take Azithromycin?
- Those who have had liver problems or jaundice while using azithromycin in the past.
- If you are allergic to similar drugs, such as clarithromycin, erythromycin, or telithromycin.
- If you have myasthenia gravis.
Advice From The Pharmacist
- Antibiotic medicines can cause diarrhea. If you have diarrhea that is watery or bloody, call your doctor right away.
- Avoid exposure to sunlight or tanning beds. Azithromycin can make you sunburn more easily.
- Do not take antacids that contain aluminum or magnesium within 2 hours before or after you take azithromycin.
Side Effects of Azithromycin
Common Side Effects
- Nausea, vomiting, diarrhea, stomach pain
- Headache
- Dizziness
- Rash
Risks and Warnings of Azithromycin
- Stomach issues: Azithromycin can upset your stomach. You might feel nauseous, vomit, or have diarrhea.
- Heart: Some people might experience heart-related issues like a fast or irregular heartbeat.
- Long QT syndrome: This is a rare heart condition, but if you or your family have it, azithromycin might not be safe for you. It can cause a serious (even deadly) heartbeat that's not normal.
Interactions with Azithromycin
Common Drug Interactions
- Warfarin
- Digoxin
- Atorvastatin
Common Food Interactions
- Avoid taking with grapefruit or grapefruit juice as it can affect azithromycin absorption.
- Maintain a balanced diet and drink lots of fluids to prevent potential side effects like nausea, vomiting and diarrhea.
Alternatives to Azithromycin
- Amoxicillin
- Doxycycline
- Ciprofloxacin
- Levofloxacin
- Clarithromycin
- Erythromycin
