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Emverm
Emverm (generic name: mebendazole) is an anthelmintic (anti-worm) medication used to treat parasitic worm infections, including pinworm, whipworm, roundworm, and hookworm. Mebendazole works by preventing the worms from absorbing sugar, causing them to lose energy and die. Emverm is commonly prescribed for the treatment of pinworm infections but is also effective against a broad range of intestinal parasites.
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Frequently Asked Questions
How long does it take for Emverm to work?
Emverm begins working quickly, and most patients experience symptom relief within a few days. In the case of pinworm infections, it kills the worms within 24-72 hours. Full recovery may take longer depending on the severity of the infection.
Can Emverm be taken during pregnancy?
Emverm is generally not recommended during pregnancy, especially in the first trimester, due to potential risks to the developing fetus. If you are pregnant, discuss alternative treatment options with your healthcare provider.
What should I do if I miss a dose?
If you miss a dose, take it as soon as you remember. If it’s close to the time for your next dose, skip the missed dose and continue with your regular schedule. Do not double up on doses.
Do I need to repeat the dose of Emverm for pinworm?
In some cases, a second dose may be required after 2 weeks to ensure all pinworms are eliminated, as re-infection can occur easily, especially in households with children.
Can I take Emverm with food?
Yes, Emverm can be taken with or without food. It is a chewable tablet, so be sure to chew the tablet thoroughly before swallowing.
Comprehensive Drug Guide
How Does Emverm Work?
Mebendazole works by selectively inhibiting the synthesis of microtubules in intestinal worms, preventing them from utilizing glucose for energy. This leads to a depletion of energy stores in the worms, resulting in their death. The dead worms are then expelled from the body through natural bowel movements.
Common Dosages
- 100 mg chewable tablet taken once for pinworm infections.
- 100 mg twice daily for 3 days for other worm infections like roundworm, hookworm, and whipworm.
Typical Dosing
- For pinworm infections, a single 100 mg dose is usually sufficient. In some cases, a second dose may be taken 2 weeks later if re-infection occurs.
- For other parasitic infections, the recommended dose is 100 mg twice daily for 3 consecutive days.
- The medication can be taken with or without food, and the chewable tablet should be thoroughly chewed before swallowing.
Typical Dosing
FDA Approved Indications
- Pinworm (Enterobius vermicularis)
- Whipworm (Trichuris trichiura)
- Roundworm (Ascaris lumbricoides)
- Hookworm (Ancylostoma duodenale or Necator americanus)
Who Shouldn't Take Emverm?
- Known hypersensitivity to mebendazole or any component of the formulation
- Pregnancy, especially during the first trimester, due to potential risks to the fetus
Advice From The Pharmacist
- Take Emverm exactly as prescribed by your healthcare provider. It is typically a single dose for pinworm infections but may require a 3-day course for other parasitic infections.
- Ensure all household members are treated simultaneously to prevent re-infection, especially for pinworm.
- Wash hands thoroughly after using the bathroom and before eating to avoid spreading pinworm eggs.
- Clean bed linens, clothing, and towels regularly to prevent further contamination.
Side Effects of Emverm
Common Side Effects
- Abdominal pain
- Nausea
- Diarrhea
- Headache
Uncommon/Severe Side Effects
- Severe allergic reactions (rash, itching, swelling, difficulty breathing)
- Liver issues (jaundice, elevated liver enzymes)
Risks and Warnings of Emverm
- Pregnancy: Mebendazole is not recommended during pregnancy, especially in the first trimester, as it may harm the fetus. Women who are pregnant or planning to become pregnant should discuss the risks and benefits with their healthcare provider.
- Liver Function: Prolonged use of mebendazole may cause liver function abnormalities, though this is uncommon. Liver function tests may be recommended if using the medication long-term.
- Re-infection: Reinfection is common with pinworms, and appropriate hygiene practices (handwashing, cleaning) are essential to prevent the spread and recurrence of infection.
Interactions with Emverm
Common Drug Interactions
- Metronidazole: Concurrent use with metronidazole has been associated with Stevens-Johnson syndrome (a rare but serious skin disorder). It is recommended to avoid using these drugs together.
- Antiepileptic Drugs: Drugs like phenytoin or carbamazepine may reduce the effectiveness of Emverm by increasing the metabolism of mebendazole.
Alternatives to Emverm
- Albendazole (Albenza): Another broad-spectrum anthelmintic used to treat various parasitic infections, including tapeworms and roundworms.
- Pyrantel Pamoate (Pin-X): An over-the-counter medication used primarily for treating pinworm infections.
- Ivermectin (Stromectol): Used for treating strongyloidiasis and other parasitic infections.
- Nitazoxanide (Alinia): An antiparasitic medication used for protozoal infections but also effective against some intestinal parasites.
