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Albendazole
Albendazole is an antiparasitic medication that's used primarily to treat certain infections caused by worms. It works by keeping the worm from absorbing sugar (glucose) so that the worm loses energy and dies. Potential side effects may include stomach pain, nausea, headaches, and dizziness. As always, your doctor will weigh the benefits over any potential side effects.
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Frequently Asked Questions
Can I drink alcohol while taking Albendazole?
It's not specifically prohibited, but alcohol can increase the chance and severity of the medication's side effects, like nausea and dizziness. Better to avoid it.
Can I take Albendazole if I'm pregnant?
No, it's generally not recommended as it can harm the unborn baby. Talk to your doctor for more specific advice.
Can I take Albendazole with food?
Yes, it's even recommended. Eating, especially a highfat meal, while you take albendazole can help your body absorb it better.
Does Albendazole have any side effects?
Yes, you might experience some stomach pain, vomiting, headache, or dizziness. If any of these get severe or persist, tell your doctor.
What should I do if I miss a dose of Albendazole?
Missing a dose might affect the success of your treatment. If it's still far from your next dose, take it as soon as you remember. If it's almost time for your next dose, just skip the missed one.
Comprehensive Drug Guide
How Does Albendazole Work?
Albendazole affects the enzymatic process in helminthic cells by inhibiting tubulin polymerization. This causes a decrease in the absorption of glucose, leading to the death of the parasite.
What is Albendazole Used For?
FDA indications: Albendazole is primarily used in the treatment of a variety of worm infections like Cysticercosis and Capillariasis
Offlabel uses: Offlabel, it can be employed to treat a broad spectrum of parasitic worm infections.
Common Dosages
Tablets: 200mg
Typical Dosing
FDA Approved Indications
- Cysticercosis: 15mg per kilogram of body weight per day, taken for 830 days
- Capillariasis: 200mg twice a day taken for 10 days.
Off-Label Uses
- Intestinal parasites: 400mg as a single dose, repeat in 2 weeks.
Who Shouldn't Take Albendazole?
- Have an allergy to albendazole, or similar drugs such as mebendazole
- Have certain types of infections (e.g Oculus and visceral larva migrans) without the supervision of a healthcare provider
- Are pregnant, planning to become pregnant, or are breastfeeding (it's not known whether albendazole harms the baby)
- Have liver or kidney disease
- Have a low white blood cell count
- Have bone marrow suppression
Advice From The Pharmacist
- Don't skip doses or stop Albendazole without your doctor's approval.
- Always take the medication with food as it improves absorption.
- It?s important to follow up and regularly get your blood tests done while on Albendazole.
- Inform your healthcare provider if you develop a fever, sore throat, mouth sores, or unusual bleeding.
- Always wash hands and maintain hygiene to prevent reinfection.
Side Effects of Albendazole
Common Side Effects
- Abdominal pain.
- Nausea or vomiting.
- Headache.
- Dizziness.
- Temporary hair loss.
Uncommon/Severe Side Effects
- Severe allergic reactions include rash, itching, swelling, severe dizziness, or trouble breathing.
- Severe side effects are rare but could include persistent sore throat or fever, severe stomach pain, or dark urine.
Risks and Warnings of Albendazole
- Albendazole treatment requires regular blood tests to monitor liver function and blood cell counts.
- Liver inflammation, injury, or failure can occur with Albendazole
- Albendazole can weaken the immune system leading to infection
- Albendazole can damage bone marrow leading to a decrease in cell production
- It has been associated with vision changes or damage
- Albendazole can cause harm to a fetus, so women should avoid getting pregnant during and for one month after treatment
- Albendazole may slow growth & weight gain in children
Interactions with Albendazole
Common Drug Interactions
- Praziquantel
- Dexamethasone
- Cimetidine
- Theophylline
Alternatives to Albendazole
- Mebendazole
- Pyrantel pamoate
- Thiabendazole
- Ivermectin
- Niclosamide
