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Caplyta
Caplyta (lumateperone) is an atypical antipsychotic used to treat schizophrenia and bipolar depression. It works by modulating neurotransmitter activity, particularly dopamine and serotonin, which helps reduce symptoms such as hallucinations, delusions, and mood swings.
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Frequently Asked Questions
How long does it take for Caplyta to start working?
It may take several weeks for the full effects of Caplyta to become noticeable. Some patients may start to see improvements in mood and behavior within the first week.
Can Caplyta cause weight gain?
Yes, weight gain is a potential side effect of Caplyta, though it may be less pronounced compared to other antipsychotic medications.
Is Caplyta used for anxiety?
Caplyta is not specifically approved for the treatment of anxiety, though it may help alleviate some symptoms in patients with schizophrenia or bipolar depression.
Can I stop taking Caplyta once I feel better?
No, you should continue taking Caplyta as prescribed by your doctor. Stopping suddenly may cause a return of symptoms.
Does Caplyta affect sleep?
Caplyta may cause drowsiness or sleep disturbances in some individuals. Talk to your healthcare provider if you experience significant changes in your sleep patterns.
Comprehensive Drug Guide
How Does Caplyta Work?
Caplyta works by affecting the activity of dopamine and serotonin receptors in the brain, helping to stabilize mood and reduce symptoms of schizophrenia and bipolar depression.
Common Dosages
- Capsules: 42 mg.
Typical Dosing
- The typical dose is 42 mg once daily, taken with or without food.
Typical Dosing
FDA Approved Indications
- Treatment of schizophrenia in adults.
- Treatment of depressive episodes in bipolar I and bipolar II disorder (bipolar depression).
Who Shouldn't Take Caplyta?
- Known hypersensitivity to lumateperone or any components of the formulation.
Advice From The Pharmacist
- Take Caplyta exactly as prescribed, even if you feel better.
- Notify your doctor if you experience unusual changes in mood, confusion, or muscle stiffness.
- Avoid drinking alcohol while taking Caplyta, as it can increase the risk of side effects.
Side Effects of Caplyta
Common Side Effects
- Drowsiness
- Dizziness
- Dry mouth
- Weight gain
Uncommon/Severe Side Effects
- Neuroleptic malignant syndrome (a life-threatening neurological disorder)
- Tardive dyskinesia (involuntary movements)
Risks and Warnings of Caplyta
- Neuroleptic malignant syndrome (NMS): A rare but serious side effect that can occur with antipsychotic medications, including Caplyta. Symptoms include fever, muscle stiffness, and confusion.
- Increased risk of death in elderly patients with dementia-related psychosis: Antipsychotics like Caplyta are not approved for treating dementia-related psychosis.
Interactions with Caplyta
Common Drug Interactions
- CYP3A4 inhibitors (e.g., ketoconazole) can increase the levels of Caplyta, potentially leading to an increased risk of side effects.
- CYP3A4 inducers (e.g., rifampin) can reduce the effectiveness of Caplyta.
Alternatives to Caplyta
- Abilify (aripiprazole): Another atypical antipsychotic for treating schizophrenia and bipolar disorder.
- Latuda (lurasidone): Commonly prescribed for bipolar depression and schizophrenia.
- Seroquel (quetiapine): Another option for treating schizophrenia and bipolar depression.
