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Aciphex
Aciphex, also known as rabeprazole, belongs to a class of drugs known as proton pump inhibitors (PPIs). It's used to reduce the amount of acid produced in your stomach, thereby treating conditions such as gastroesophageal reflux disease (GERD), ulcers, and ZollingerEllison Syndrome. The most common side effects are headache, nausea, vomiting, and diarrhea, which usually go away over time.
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Frequently Asked Questions
Can I stop taking Aciphex if I feel better?
Don't stop taking Aciphex without consulting your doctor, even if you start to feel better. Stopping suddenly can cause a rebound effect, worsening your acid reflux.
Can I take Aciphex if I am pregnant?
It should only be used during pregnancy if the benefits outweigh the risks. Talk to your healthcare provider to discuss the best options for you and your baby.
Does Aciphex interfere with other medications?
Yes, some medications can interact with Aciphex and may not work as well, or may cause serious side effects. Talk to your doctor or pharmacist about all your medications to prevent dangerous interactions.
I missed a dose of Aciphex, what should I do?
If it's close to your next dose, skip the missed one. If not, take it as soon as you remember. But never double up doses!
Comprehensive Drug Guide
How Does Aciphex Work?
Aciphex functions by inhibiting the final step in gastric acid production, therefore decreasing the amount of acid produced in the stomach.
What is Aciphex Used For?
Aciphex is used to treat gastroesophageal reflux disease (GERD), a condition in which backward flow of acid from the stomach causes heartburn and possible injury to the esophagus. It is also used to treat conditions where the stomach produces too much acid, such as ZollingerEllison syndrome.
Offlabel uses:
It's also been used for the offlabel treatment of functional dyspepsia.
Common Dosages
Tablets: 20mg
Delayedrelease tablets: 20mg
Typical Dosing
FDA Approved Indications
- For FDAapproved indications:
- Gastroesophageal Reflux Disease (GERD): 20mg per day for 4 to 8 weeks.
- ZollingerEllison Syndrome: The initial dose is 60mg once daily. A healthcare provider might adjust the dose as necessary.
Off-Label Uses
- For offlabel uses:
- Functional dyspepsia: 20mg per day for 4 to 12 weeks.
Who Shouldn't Take Aciphex?
- Have had a severe allergic reaction to rabeprazole or any other proton pump inhibitors in the past.
- Have a rare hereditary problem of fructose intolerance (Aciphex tablets contain sucrose).
- Have osteoporosis or risk factors for developing osteoporosis.
- Are pregnant, planning to become pregnant, or breastfeeding.
- Have liver problems or diseases.
- Have low magnesium levels in your blood.
Advice From The Pharmacist
- Take Aciphex once a day, first thing in the morning. It?ll keep stomach acid at bay all day.
- Don?t chew, crush, or split the tablet. Swallow it whole.
- It can take several days to start seeing the effects. Don?t stop taking it if you don?t get immediate relief.
- If you miss a dose, take it as soon as possible, unless it's near the time for your next dose. Don't double up.
- If you?ve been on Aciphex for a while, don?t stop suddenly ? it could make your acid problems return with a vengeance!
- Eating smaller, more frequent meals can also help manage your acid reflux.
- Raise the head of your bed to help gravity keep stomach acid where it belongs
Side Effects of Aciphex
Common Side Effects
- Headache
- Nausea
- Vomiting
- Diarrhea
- Stomach pain
Uncommon/Severe Side Effects
- Rare side effects:
- Joint pain
- Dizziness
- Depression
- Severe side effects:
- Serious allergic reactions ? watch for hives, difficulty breathing, and swelling of your face, lips, tongue, or throat.
- Low magnesium levels ? watch for fast, irregular heartbeat, jitteriness, muscle weakness, and spasms.
Risks and Warnings of Aciphex
- Some people who take Aciphex for a long time may develop weakened bone, especially if they do not eat a balanced diet or do not have enough Vitamin D or calcium in their blood. Make sure to have regular bone checkups.
- Longterm use of Aciphex may also make it harder for your body to absorb vitamin B12, leading to a deficiency.
- Women who are pregnant should use Aciphex only if the potential benefit justifies the potential risk to the fetus.
- Aciphex should be used with caution in people with severe liver problems.
Interactions with Aciphex
Common Drug Interactions
- Atazanavir
- Methotrexate
- Warfarin
- Digoxin
- Ketoconazole
- Theophylline
- Cyclosporine
Alternatives to Aciphex
- Nexium
- Prilosec
- Prevacid
- Protonix
- Dexilant
- Zegerid
