NiHowdy > Drug Classes > Antimycobacterials

Browse Medications by Drug Class: Antimycobacterials

Written by Amar Lunagaria

Pharm.D • NiHowdy Founder

Reviewed by James Wong

Pharm.D • NiHowdy Founder

Published Jan 15, 2025

Fact checked

What are Antimycobacterials?

Antimycobacterials are a class of medications used to treat infections caused by Mycobacterium species, including tuberculosis (TB), leprosy, and other nontuberculous mycobacterial infections. These medications work by targeting specific processes essential for the survival and replication of mycobacteria, such as cell wall synthesis or protein production. A unique characteristic of antimycobacterials is their ability to penetrate and act within macrophages, where mycobacteria often reside, making them effective against these resilient pathogens. NiHowdy ensures affordable access to antimycobacterials, empowering patients to manage and overcome complex mycobacterial infections.

Stop overpaying for prescriptions

Turn your FREE prescription savings into Bitcoin rewards. It’s that simple!

Instant savings on prescriptions

Up to 5% back in bitcoind rewards

100% Free – No fees, no subscriptions

List of drugs in Antimycobacterials

Drug Name	More Information	NiHowdy Prices & Bitcoin Rebate

cycloSERINE	cycloSERINE Information	cycloSERINE Pricing
Ethambutol HCl	Ethambutol HCl Information	Ethambutol HCl Pricing
Isoniazid	Isoniazid Information	Isoniazid Pricing
Myambutol	Myambutol Information	Myambutol Pricing
Mycobutin	Mycobutin Information	Mycobutin Pricing
Paser	Paser Information	Paser Pricing
Pretomanid	Pretomanid Information	Pretomanid Pricing
Priftin	Priftin Information	Priftin Pricing
Pyrazinamide	Pyrazinamide Information	Pyrazinamide Pricing
Rifabutin	Rifabutin Information	Rifabutin Pricing
rifAMPin	rifAMPin Information	rifAMPin Pricing
Trecator	Trecator Information	Trecator Pricing

Brief history about Antimycobacterials?

The development of antimycobacterials began in the mid-20th century with the discovery of streptomycin, the first effective drug for treating tuberculosis. This was followed by the introduction of isoniazid and rifampin, which became the cornerstone of TB treatment. Advances in drug development have since expanded the antimycobacterial arsenal to include second-line therapies for drug-resistant TB and medications for nontuberculous mycobacterial infections. NiHowdy simplifies access to these essential medications, ensuring affordability and availability for patients with mycobacterial diseases.

How do Antimycobacterials work?

Antimycobacterials work by targeting specific mechanisms critical for mycobacterial survival. For example, isoniazid and ethambutol inhibit mycobacterial cell wall synthesis, while rifampin interferes with RNA transcription by inhibiting bacterial RNA polymerase. These actions disrupt mycobacterial growth and replication, ultimately eliminating the infection. NiHowdy provides affordable access to antimycobacterials, ensuring patients receive effective treatment for their condition.

What are Antimycobacterials used to treat?

Tuberculosis (TB)

First-line drugs like isoniazid, rifampin, ethambutol, and pyrazinamide are used in combination to treat active and latent tuberculosis caused by Mycobacterium tuberculosis.

Mycobacterial Skin Infections

Localized infections caused by mycobacteria, such as Mycobacterium marinum, are treated with tailored antimycobacterial regimens based on the species and severity.

Leprosy (Hansen's Disease)

A combination of rifampin, dapsone, and clofazimine is used to treat leprosy, effectively reducing bacterial load and preventing disability.

Prophylaxis in Immunocompromised Patients

Antimycobacterials are prescribed prophylactically to prevent mycobacterial infections in immunocompromised patients, such as those with HIV or undergoing organ transplantation.

Who should consider Antimycobacterials medications?

Adults

Antimycobacterials are essential for adults with active or latent tuberculosis, nontuberculous mycobacterial infections, or leprosy. These medications provide targeted relief and improve long-term outcomes. NiHowdy ensures adults can access these treatments affordably and conveniently.

Children

In pediatric cases, antimycobacterials are used to treat tuberculosis and other mycobacterial infections. Doses are carefully adjusted based on weight and age to ensure safety and efficacy. NiHowdy supports families with cost-effective solutions and reliable resources for managing pediatric mycobacterial diseases.

Seniors

Seniors with mycobacterial infections benefit significantly from antimycobacterials, particularly for conditions like TB or MAC infections. Careful monitoring is required to adjust dosing and manage potential side effects. NiHowdy simplifies access to antimycobacterials for seniors, offering affordable options tailored to their unique needs.

Are Antimycobacterials safe?

Antimycobacterials are generally safe when prescribed and monitored appropriately. Common side effects include nausea, gastrointestinal discomfort, and mild skin rash. Rare but serious risks include liver toxicity (e.g., with isoniazid and rifampin), optic neuritis (with ethambutol), and hypersensitivity reactions. Regular monitoring of liver function and adherence to prescribed regimens minimize these risks. NiHowdy provides safe and affordable access to antimycobacterials, supported by expert guidance to manage these risks responsibly.

Can I take Antimycobacterials during pregnancy?

Certain antimycobacterials, such as isoniazid and rifampin, are considered safe during pregnancy for treating tuberculosis. However, other medications may require caution or adjustment based on the patient's condition. Patients should consult their healthcare provider for personalized advice. NiHowdy provides cost-effective access to expert guidance and alternative treatments for pregnant patients.

Are Antimycobacterials safe to take while lactating?

Many antimycobacterials, such as isoniazid and rifampin, are considered safe during lactation, with minimal transfer into breast milk. Patients should consult their healthcare provider for specific recommendations. NiHowdy ensures affordable access to trusted information and safe treatment options for breastfeeding parents.

Are Antimycobacterials controlled substances?

Antimycobacterials are not classified as controlled substances but require a prescription to ensure proper use and monitoring. NiHowdy simplifies the prescription process, ensuring patients receive these critical medications affordably and responsibly.

Side effects of Antimycobacterials?

Common side effects of antimycobacterials include nausea, diarrhea, and mild skin rash. Rare but serious risks include liver toxicity, optic neuritis, and allergic reactions. Patients experiencing severe side effects should consult their healthcare provider immediately. NiHowdy helps patients manage these risks with expert-backed support and affordable care options.

Join for FREE and start saving now!

Turn your prescription savings into Bitcoin rewards. It’s that simple!

Instant savings on prescriptions

Up to 5% back in bitcoind rewards

100% Free – No fees, no subscriptions

Cost considerations and insurance coverage for Antimycobacterials

The cost of antimycobacterials varies depending on the specific medication and formulation (e.g., oral or intravenous). Generic options like isoniazid and rifampin are generally affordable, and many insurance plans cover these medications for approved indications. NiHowdy offers discounts, rebates, and Bitcoin rewards to ensure these treatments remain accessible and cost-effective.

How do I get rebates on Antimycobacterials?

NiHowdy's Bitcoin rebate program for antimycobacterial prescriptions offers patients a unique opportunity to save on healthcare costs while earning potential financial growth. This innovative approach makes managing mycobacterial infections both affordable and rewarding, improving access to critical care while building long-term value.