NiHowdy > Therapeutic Classes > Selective Estrogen Receptor Modulators (Osteoporosis)

Browse Medications by Therapeutic Class: Selective Estrogen Receptor Modulators (Osteoporosis)

Written by Amar Lunagaria

Pharm.D • NiHowdy Founder

Reviewed by James Wong

Pharm.D • NiHowdy Founder

Updated Jan 27, 2025

•

Published Jan 15, 2025

Fact checked

What are Selective Estrogen Receptor Modulators (Osteoporosis)?

Selective Estrogen Receptor Modulators (SERMs) are medications that mimic or block the effects of estrogen in different tissues. They are commonly used to treat osteoporosis in postmenopausal women by improving bone density and reducing the risk of fractures. SERMs provide the benefits of estrogen on bones without increasing the risk of certain hormone-related cancers.

How do Selective Estrogen Receptor Modulators (Osteoporosis) work?

SERMs work by selectively activating estrogen receptors in specific tissues. In bones, they mimic estrogen's effects to:

Increase bone density.
Reduce bone turnover, slowing bone loss.
Decrease the risk of spine and hip fractures.

At the same time, SERMs block estrogen in breast and uterine tissues, reducing the risk of hormone-related cancers.

What conditions do Selective Estrogen Receptor Modulators (Osteoporosis) treat?

SERMs are commonly prescribed to treat:

Osteoporosis: Prevents and treats bone loss in postmenopausal women.
Breast cancer prevention: In high-risk individuals (for certain SERMs).
Other estrogen-related conditions: Where selective estrogen effects are beneficial.

These medications are essential for improving bone health while minimizing hormonal risks.

Common medications in Selective Estrogen Receptor Modulators (Osteoporosis)s

Popular SERM medications include:

Raloxifene (Evista): Primarily used to treat and prevent osteoporosis in postmenopausal women.
Tamoxifen (Nolvadex): Prevents and treats hormone-receptor-positive breast cancer but also helps protect bone density in certain cases.
Bazedoxifene (Duavee): Combined with estrogen for osteoporosis prevention and relief of menopausal symptoms.

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List of drugs in Selective Estrogen Receptor Modulators (Osteoporosis)

Drug Name	More Information	NiHowdy Prices & Bitcoin Rebate

Duavee

Duavee Information

Duavee Pricing

Benefits of Selective Estrogen Receptor Modulators (Osteoporosis)

The benefits of SERMs include:

Improved bone density, reducing the risk of fractures.
Hormonal selectivity, offering bone health benefits without the risks of traditional hormone replacement therapy.
Additional protection against certain hormone-related cancers.

At NiHowdy, we make these benefits accessible with affordable pricing and Bitcoin rebates, empowering you to prioritize your bone health without financial worries.

Side effects of Selective Estrogen Receptor Modulators (Osteoporosis)

While SERMs are effective, they may cause potential side effects, such as:

Hot flashes or leg cramps.
Mild nausea or digestive discomfort.
Rare risk of blood clots (e.g., deep vein thrombosis or pulmonary embolism).

These medications are safe when used as prescribed by your healthcare provider. NiHowdy helps you afford these treatments, so you can focus on managing your bone health without financial stress.

How NiHowdy helps with Selective Estrogen Receptor Modulators (Osteoporosis)

NiHowdy supports your journey to stronger bones and better health by offering savings on SERM medications. Every purchase includes Bitcoin rebates, providing financial value while ensuring you have access to effective osteoporosis treatments.

NiHowdy success story

Meet Maria, a postmenopausal woman diagnosed with osteoporosis. By using Raloxifene prescribed through NiHowdy, Maria saved $30 on her medication and earned Bitcoin rebates. These savings allowed her to protect her bone health while staying within her budget.

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