You're not logged in. Please log in to earn stock or Bitcoin rewards on your prescription purchase.
ZyPREXA Relprevv
Zyprexa Relprevv (olanzapine pamoate) is an atypical antipsychotic medication used for the long-term treatment of schizophrenia in adults. It is an extended-release injectable formulation designed to be administered once every 2 to 4 weeks. Zyprexa Relprevv helps manage symptoms such as hallucinations, delusions, and disorganized thinking by affecting the levels of dopamine and serotonin in the brain. It is used in patients who have responded well to oral olanzapine but need a long-acting option for better treatment adherence.
Rx. Enter your prescription
How would you like to get your prescription? Select an option
Pharmacy pickup
Select from 35,000 pharmacies
Free two-day delivery
Coming soon!
Find a pharmacy near you. Enter your ZIP code
Are you a member? Sign up or log in.
Members have saved
$NaN
using our savings card for instant savings.
Don't pay full retail price and miss out on potential savings. Try it now—you have nothing to lose!
NaNM
worth of Satoshi has been rewarded to our members.
Everyone who signs up enjoys the benefits of earning FREE Bitcoin with every purchase.
How much Bitcoin can you earn with ZyPREXA Relprevv ?
The potential for Bitcoin rewards to increase and appreciate in value is a possibility to consider, which may occur over time.
See the value of your savings today
Today's Value
1 Bitcoin = $NaN
Bitcoin (BTC)
...
USD
$NaN
Adjust Bitcoin's potential value to see how much it could be worth
Potential Value
1 Bitcoin =
Bitcoin (BTC)
...
USD
$NaN
Frequently Asked Questions
What is Post-Injection Delirium/Sedation Syndrome (PDSS)?
PDSS is a rare but serious reaction that can occur after receiving Zyprexa Relprevv. Symptoms include confusion, excessive sedation, or even coma-like states. Due to this risk, patients must be monitored for at least 3 hours after each injection.
How long does Zyprexa Relprevv last?
Zyprexa Relprevv is a long-acting injectable that lasts for either 2 or 4 weeks, depending on the dosage prescribed. The injection releases olanzapine gradually over time to maintain stable levels in the body.
Can I drive after receiving Zyprexa Relprevv?
No, you should not drive or operate heavy machinery for the rest of the day after receiving a Zyprexa Relprevv injection due to the potential for sedation and drowsiness.
What should I do if I miss a scheduled injection?
If you miss a scheduled injection, contact your healthcare provider as soon as possible to reschedule. It is important to stay on a regular injection schedule to maintain consistent levels of the medication.
Does Zyprexa Relprevv cause weight gain?
Yes, weight gain is a common side effect of Zyprexa Relprevv. Patients should have their weight and metabolic parameters, such as blood sugar and cholesterol levels, monitored regularly during treatment.
Comprehensive Drug Guide
How Does ZyPREXA Relprevv Work?
Zyprexa Relprevv works by modulating the levels of dopamine and serotonin in the brain. By reducing the activity of these neurotransmitters, it helps control symptoms of schizophrenia such as delusions, hallucinations, and thought disturbances. Its long-acting formulation provides steady levels of the medication over weeks, reducing the need for daily dosing and improving adherence.
Common Dosages
- 210 mg (every 2 weeks)
- 300 mg (every 2 weeks)
- 405 mg (every 4 weeks)
Typical Dosing
- For patients stabilized on oral olanzapine: The typical starting dose of Zyprexa Relprevv is based on the previous oral dosage, with injections given every 2 or 4 weeks.
- 210 mg or 300 mg every 2 weeks or 405 mg every 4 weeks is commonly used depending on the patient’s clinical condition and tolerance.
Typical Dosing
FDA Approved Indications
- Schizophrenia in adults
Who Shouldn't Take ZyPREXA Relprevv?
- Known hypersensitivity to olanzapine or any components of the formulation.
- A history of post-injection delirium/sedation syndrome (PDSS) related to previous use of Zyprexa Relprevv.
Advice From The Pharmacist
- Zyprexa Relprevv must be administered by a healthcare provider in a clinical setting due to the risk of post-injection delirium/sedation syndrome (PDSS). Patients will need to be monitored for at least 3 hours after each injection.
- Patients receiving Zyprexa Relprevv should continue regular visits to their healthcare provider for ongoing evaluation and administration.
- The injection is administered into the buttock or thigh muscle by a trained healthcare provider, and patients should not drive or operate heavy machinery for the rest of the day after receiving the injection.
Side Effects of ZyPREXA Relprevv
Common Side Effects
- Drowsiness or sedation
- Weight gain
- Increased appetite
- Dry mouth
- Constipation
Uncommon/Severe Side Effects
- Post-injection delirium/sedation syndrome (PDSS): A rare but serious reaction where patients may experience sedation, confusion, or coma-like symptoms shortly after the injection.
- Tardive dyskinesia: Involuntary movements, particularly of the face and tongue, which can become permanent with long-term use.
- Neuroleptic malignant syndrome (NMS): A rare but life-threatening reaction characterized by muscle rigidity, fever, and altered mental status.
Risks and Warnings of ZyPREXA Relprevv
- Post-injection Delirium/Sedation Syndrome (PDSS): This syndrome occurs rarely but is a serious reaction to Zyprexa Relprevv, leading to excessive sedation and confusion shortly after the injection. Patients must remain in a healthcare setting for at least 3 hours post-injection to be monitored for PDSS.
- Weight Gain and Metabolic Changes: Zyprexa Relprevv is associated with significant weight gain and metabolic changes such as increased blood sugar and cholesterol. Regular monitoring of weight and metabolic parameters is necessary.
- Tardive Dyskinesia: Long-term use of Zyprexa Relprevv may lead to tardive dyskinesia, a potentially irreversible movement disorder.
- Neuroleptic Malignant Syndrome (NMS): A rare but serious reaction that requires immediate medical attention if symptoms occur.
Interactions with ZyPREXA Relprevv
Common Drug Interactions
- CNS depressants: Combining Zyprexa Relprevv with alcohol or sedative medications (such as benzodiazepines or opioids) can increase drowsiness and sedation.
- Antihypertensive medications: Zyprexa Relprevv may enhance the effects of blood pressure-lowering drugs, leading to an increased risk of low blood pressure.
- Carbamazepine: This medication may decrease the blood levels of olanzapine, reducing its effectiveness.
Alternatives to ZyPREXA Relprevv
- Invega Sustenna (paliperidone palmitate): A long-acting injectable antipsychotic for schizophrenia, administered monthly.
- Abilify Maintena (aripiprazole): Another long-acting injectable used to treat schizophrenia and bipolar disorder.
- Risperdal Consta (risperidone): A biweekly injectable antipsychotic for the treatment of schizophrenia.
