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Repaglinide

Repaglinide is a type of medication used to control high blood sugar in people with type 2 diabetes. It works by causing the pancreas to release more insulin into the bloodstream, reducing glucose levels.

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Frequently Asked Questions

Can I take repaglinide if I have liver disease?
Open FAQClose FAQ

Probably not. Repaglinide is not recommended for individuals with severe liver disease. Always consult your doctor.

Does repaglinide cause weight gain?
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Yes, weight gain is a possible side effect.

I missed a dose of repaglinide, what should I do?
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If it's almost time for your next dose, skip the missed one. If it's not, take it as soon as you remember.

Can I just stop taking repaglinide after my sugar levels are controlled?
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No, you should always speak to your doctor before stopping this medication to avoid rebound high sugar levels.

Comprehensive Drug Guide

How Does Repaglinide Work?

Repaglinide is an antidiabetic drug that works by stimulating the beta cells of the pancreas to release insulin, which helps lower blood glucose levels.

What is Repaglinide Used For?

FDA indications: Repaglinide is used in conjunction with diet and exercise to control high blood sugar levels in people with type 2 diabetes, reducing their risk of kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems.Off-label uses: Not typically used off-label.

Common Dosages

Tablets: 0.5mg, 1mg, 2mg

Typical Dosing

FDA Approved Indications

  • Based on individual needs and responses, to lower blood glucose without causing hypoglycemia. The initial dose might start at 0.5 mg before each meal. I
  • t is advised to take repaglinide 15 to 30 minutes before meals.

Who Shouldn't Take Repaglinide?

  • Have severe liver disease. Are in a state of diabetic ketoacidosis. Are allergic to repaglinide or any of its ingredients. Are pregnant or planning to become pregnant. Are breastfeeding.

Advice From The Pharmacist

  • Try to perform regular physical activity. It helps to control your blood sugar levels. Make sure to follow the dietary plan recommended by your doctor. Take this medication with food to avoid an upset stomach. If you develop any symptoms of hypoglycemia such as dizziness, sweating, or heartbeat change, make sure to consume some form of sugar immediately. Do not skip meals. Skipping a meal increases the risk of hypoglycemia. Regularly monitor your blood glucose levels, especially in the beginning. Be aware that some medicines may influence the action of repaglinide. Always check the compatibility of a new medication with your doctor.

Side Effects of Repaglinide

Common Side Effects

  • Low blood sugar (hypoglycemia) can happen. You could experience diarrhea or constipation. Unusual weight gain may be observed.

Uncommon/Severe Side Effects

  • Uncommon side effects: Blurred vision might unsettle you. Nervousness or shaking (tremors) could occur. You might start feeling dizzy or tired. Rare side effects: Pain or swelling in your joints may occur. Skin rash or itching might appear. Severe side effects: Symptoms of liver disease (such as yellowing eyes/skin, dark urine, and persistent nausea/vomiting) should not be taken lightly. If you notice signs of a serious allergic reaction like rash, itching, or swelling of the face/tongue/throat, severe dizziness, or trouble breathing, seek immediate medical assistance.

Risks and Warnings of Repaglinide

  • Remember that Repaglinide, while effective, is not for everyone. It's not recommended for those with severe liver disease or in individuals in a state of diabetic ketoacidosis. Pregnant women, individuals planning to become pregnant, or breastfeeding should consult with a healthcare provider before taking repaglinide. Individuals sensitive to repaglinide or any of its ingredients should avoid taking this medication.

Interactions with Repaglinide

Common Drug Interactions

  • Common Drug Interactions Gemfibrozil. Nifedipine. Warfarin. Other diabetes medications.

Alternatives to Repaglinide

  • Nateglinide. Sulfonylureas like glipizide, glyburide, and glimepiride. Biguanides like metformin.