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Nateglinide

The primary function of Nateglinide, a known anti-diabetic medication, is to bring your high blood sugar levels back to normal. It is specifically manufactured to control the levels of sugar after your meals, which is crucial for people troubled by type 2 diabetes.

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Frequently Asked Questions

Can I take Nateglinide if I have liver disease?
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You should consult your doctor before taking Nateglinide if you have liver disease. The drug could be more potent in such cases, and careful monitoring would be required.

Will Nateglinide affect my weight?
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Yes, Nateglinide can lead to weight gain. Your doctor may recommend a diet and exercise routine to control your weight if you are on this medication.

Can I take Nateglinide if I have type 1 diabetes?
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No, Nateglinide is not indicated for treating type 1 diabetes.

I forgot to take my Nateglinide before my meal, should I take it after?
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If you forget to take your dose before a meal, skip the missed dose and return to your usual dosing schedule by taking the next dose before your next meal.

Can I stop taking Nateglinide if my blood sugar is controlled?
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No, you should not stop taking Nateglinide even if your blood sugar is under control, unless your doctor tells you to. This drug contributes to maintaining your healthy blood sugar levels.

Comprehensive Drug Guide

How Does Nateglinide Work?

Nateglinide is a quick-acting oral antihyperglycemic agent that stimulates insulin release from the functioning beta cells of the pancreas, reducing postprandial blood glucose levels.

What is Nateglinide Used For?

FDA indications: Nateglinide is used along with diet and exercise to improve blood sugar control in patients with type 2 diabetes.

Off-label uses: Not commonly used off-label.

Common Dosages

Tablets: 60mg, 120mg

Typical Dosing

FDA Approved Indications

  • For FDA-approved indications: Type 2 Diabetes: 120mg three times per day right before each meal.

Off-Label Uses

  • For off-label uses: Not commonly used off-label.

Who Shouldn't Take Nateglinide?

  • Are known to be hypersensitive to the drug or any ingredient in the formulation.
  • Have type 1 diabetes or diabetic ketoacidosis.
  • Patients with severe infections, and low blood glucose levels (hypoglycemia).
  • Pregnant or planning to become pregnant or breastfeeding (unless prescribed by the healthcare provider).

Advice From The Pharmacist

  • - Do not skip meals while taking Nateglinide. If you do skip a meal, avoid taking your dose for that particular meal.
  • - Always take it right before your meal so it can work best.
  • - Pay close attention to symptoms of low blood sugar, such as sweating, shaking, heart palpitations. and confusion.
  • - If you experience severe and persistent symptoms of low blood sugar, seek immediate medical help.
  • - Alcohol intake should be minimized as it may spike sugar levels in the blood.
  • - Follow a healthy eating plan and regular exercise routine.

Side Effects of Nateglinide

Common Side Effects

  • - Common side effects:- Symptoms of low blood sugar (hypoglycemia) like dizziness, sweating, rapid heartbeat, and shaking.

Uncommon/Severe Side Effects

  • - Uncommon side effects:- You might feel nausea or diarrhea.
  • - Weight gain can occur.
  • - You might experience back pain.
  • - You might suffer from cough or flu-like symptoms.
  • - Severe side effects:- Allergic reactions include rashes, itching/swelling (especially on the face/tongue/throat), severe dizziness, and breathing difficulty.

Risks and Warnings of Nateglinide

  • This medication has a chance of causing hypoglycemia and should be taken exactly as prescribed.
  • Patients with liver or kidney problems should inform the doctor before starting this medication.

Interactions with Nateglinide

Common Drug Interactions

  • Beta-blockers
  • Salicylates
  • Monoamine oxidase inhibitors
  • Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
  • Certain herbs and supplements like ginseng

Alternatives to Nateglinide

  • Glimepiride
  • Glipizide
  • Glyburide
  • Metformin
  • Repaglinide