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glipiZIDE
Glipizide is an oral medication used to control blood sugar levels in people with type 2 diabetes, it falls under the category of drugs known as sulfonylureas which stimulate the pancreas to release more insulin. Common side effects include dizziness, diarrhea, and headache, but your healthcare provider will ensure that the benefits of the drug outweigh these minor issues.
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Frequently Asked Questions
Can Glipizide cause weight gain?
Yes, weight gain is a common side effect of Glipizide and other sulfonylureas.
Can Glipizide be taken with insulin?
Yes, Glipizide can be used in combination with insulin in patients who are not achieving adequate blood sugar control on insulin alone.
Can I stop taking Glipizide abruptly?
No, you should not stop taking Glipizide abruptly as this could cause your blood sugar to spike. Consult your healthcare provider for advice on discontinuing or reducing the dose safely.
Is Glipizide safe during pregnancy?
Glipizide falls under the FDA's Category C for pregnancy. This means potential benefits may warrant the use of the drug in pregnant women despite potential risks. It's advisable to consult with your healthcare provider for the best course of action.
Can Glipizide cause hypoglycemia?
Yes, one of the side effects of Glipizide is hypoglycemia or low blood sugar. It's important to recognize the symptoms of hypoglycemia--like sweating, trembling, hunger, and confusion--and take corrective measures promptly.
Comprehensive Drug Guide
How Does glipiZIDE Work?
Glipizide is an oral antidiabetic medication that stimulates the release of insulin from the beta cells of the pancreas. It works by increasing the sensitivity of insulin receptors thereby ensuring more effective utilization of circulating insulin.
What is glipiZIDE Used For?
FDA indications: Glipizide is used to control high blood sugar in people with type 2 diabetes. It's often used alongside a proper diet and exercise to control diabetes effectively.
Off-label uses: It's not commonly used off-label. But as a sulfonylurea, it's primarily used to control high blood sugar levels in type 2 diabetes patients.
Common Dosages
Tablets: 5mg, 10mg
Extended Release Tablets: 2.5mg, 5mg, 10mg
Typical Dosing
FDA Approved Indications
- FDA-approved indications:
- Diabetes management: Start with 5mg per day, which can be increased every few days but not more than 40mg per day.
Off-Label Uses
- Off-label uses: It's not commonly used off-label. But as a sulfonylurea, it's primarily used to control high blood sugar levels in type 2 diabetes patients.
Who Shouldn't Take glipiZIDE?
- Persons allergic to sulfonylureas.
- Those with diabetic ketoacidosis.
- Anyone with type 1 diabetes.
- Pregnant women, unless necessary.
- Those with severe kidney or liver disease.
- Persons with G6PD deficiency.
Advice From The Pharmacist
- Maintain a regular exercise routine and diet to ensure well-managed blood sugar levels.
- Take Glipizide about 30 minutes before a meal.
- Regular blood sugar testing is advised to adjust your dosage according to your needs.
- Don't suddenly stop taking the drug as it can lead to high blood sugar levels.
- Report any symptoms of hypoglycemia like shaking, excessive sweating, or rapid heartbeat.
- It is important to maintain regular doctor appointments for check-ups and blood tests.
Side Effects of glipiZIDE
Common Side Effects
- Common side effects: Dizziness, diarrhea, and tremors.
Uncommon/Severe Side Effects
- Rare side effects: Yellowing of the skin or eyes (jaundice).
- Severe side effects: Unusual tiredness, dark urine, and allergic reaction signs like swelling face/lips, dizziness, and difficulty in breathing.
Risks and Warnings of glipiZIDE
- Extra caution is advised when using glipizide if you have a history of liver or kidney disease, heart disease, G6PD deficiency, or hormonal disorders.
- Elderly patients are more likely to have reduced kidney function and require dosage adjustment.
- Hypoglycemia, or low blood sugar, is a major concern and constant sugar monitoring is necessary.
Interactions with glipiZIDE
Common Drug Interactions
- Beta-Blockers
- Anti-Fungal Medications
- Common Food Interactions
- Avoid consumption of alcohol as it can lower your blood sugar excessively.
Common Food Interactions
- Watch the intake of alcohol as it may increase the risk of low blood sugar.
- Follow diet instructions provided by the healthcare provider
Alternatives to glipiZIDE
- Metformin
- Insulin
- DPP-4 Inhibitors
