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Relpax
Relpax (eletriptan) is a prescription medication used to treat migraine headaches with or without aura. It belongs to the triptan class of drugs, which are serotonin receptor agonists designed to narrow blood vessels in the brain and reduce the inflammation that leads to migraines. Relpax is typically used after a migraine has started, helping to relieve symptoms such as headache, nausea, and sensitivity to light and sound, but it is not intended to prevent future migraines.
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Frequently Asked Questions
How quickly does Relpax work?
Relpax typically starts to work within 30 minutes to 2 hours of taking it, helping to alleviate migraine symptoms.
Can Relpax prevent migraines?
No, Relpax is used to treat migraines once they start. It is not intended for the prevention of migraines or other types of headaches.
What should I do if my migraine returns after taking Relpax?
If your migraine returns after the initial dose, you may take a second dose at least 2 hours after the first. Do not exceed the maximum dose of 80 mg in 24 hours.
Can I take Relpax with other pain medications?
Avoid taking Relpax with other triptans or ergotamine-based medications within 24 hours. However, over-the-counter pain relievers like ibuprofen may be taken if advised by your doctor.
Are there any dietary restrictions while taking Relpax?
There are no specific dietary restrictions with Relpax, but it is important to stay hydrated and avoid alcohol, as it may trigger or worsen migraine symptoms.
Comprehensive Drug Guide
How Does Relpax Work?
Relpax works by stimulating 5-HT1 receptors in the brain, which causes the constriction of dilated blood vessels around the brain and reduces the release of substances that contribute to inflammation and pain. This action helps alleviate the symptoms of an acute migraine attack, including pain, nausea, and sensitivity to light and sound.
Common Dosages
- Tablets: 20 mg and 40 mg
Typical Dosing
- For migraine treatment: The usual starting dose is 20 mg or 40 mg, taken at the onset of a migraine. If the migraine returns or the first dose is not fully effective, a second dose may be taken after at least 2 hours. The maximum daily dose should not exceed 80 mg.
Typical Dosing
FDA Approved Indications
- Acute migraine attacks with or without aura in adults
Who Shouldn't Take Relpax?
- A history of heart disease, coronary artery disease, or uncontrolled high blood pressure
- Hemiplegic or basilar migraines
- Severe liver impairment
- Known hypersensitivity to eletriptan or any of its components
Advice From The Pharmacist
- Take Relpax as soon as you notice the signs of a migraine, but it can still be effective if taken later during the headache phase.
- Do not exceed the maximum recommended dose of 80 mg in 24 hours.
- Avoid using Relpax within 24 hours of taking another triptan or ergotamine-based medication.
- Notify your doctor if you experience symptoms such as chest pain, shortness of breath, or severe stomach pain, as these may indicate rare but serious side effects.
- Relpax is not intended for the prevention of migraines or the treatment of other types of headaches.
Side Effects of Relpax
Common Side Effects
- Dizziness
- Nausea
- Fatigue
- Dry mouth
Uncommon/Severe Side Effects
- Heart attack or other cardiac issues
- Serotonin syndrome (especially when combined with other serotonergic drugs)
- Stroke
- Allergic reactions, such as rash or difficulty breathing
Risks and Warnings of Relpax
- Cardiovascular Risks: Relpax may increase the risk of heart attack, stroke, or angina, particularly in patients with risk factors for heart disease. It should not be used by those with existing heart conditions.
- Serotonin Syndrome: When combined with other medications that affect serotonin levels, such as SSRIs or SNRIs, Relpax may increase the risk of serotonin syndrome, a potentially life-threatening condition. Symptoms include confusion, agitation, rapid heart rate, and muscle rigidity.
- Medication Overuse Headache: Overuse of Relpax or other triptans can lead to rebound headaches. It is important to use Relpax only as directed by your healthcare provider.
Interactions with Relpax
Common Drug Interactions
- Other triptans or ergot-containing drugs: Taking these within 24 hours of Relpax can increase the risk of side effects like heart problems or high blood pressure.
- SSRIs or SNRIs: These antidepressants can raise the risk of serotonin syndrome when used with Relpax.
- CYP3A4 inhibitors (e.g., ketoconazole, erythromycin): Can increase blood levels of Relpax, leading to a higher risk of side effects. Dose adjustments may be required.
Alternatives to Relpax
- Sumatriptan (Imitrex): Another triptan used to treat acute migraines.
- Rizatriptan (Maxalt): A fast-acting triptan that can be taken orally or as an orally disintegrating tablet.
- Zolmitriptan (Zomig): Available as a tablet, nasal spray, or orally disintegrating tablet for migraine relief.
- Over-the-counter NSAIDs: Such as ibuprofen or naproxen, used for mild to moderate migraines.
