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ZOLMitriptan
Zolmitriptan is a type of medication known as a triptan, used specifically to treat migraines. It relieves headaches, nausea, and other symptoms of migraines, making life more bearable. Common side effects include feelings of tingling, drowsiness, and fatigue.
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Frequently Asked Questions
Can I take Zolmitriptan if I am pregnant?
Zolmitriptan falls under pregnancy category C, which means we do not know if it'll harm an unborn baby. It's best to consult your healthcare provider if you're pregnant or planning a pregnancy.
Can I take Zolmitriptan if I have heart problems?
Zolmitriptan can cause serious heart problems. Do not take it if you have a history of these conditions without discussing it with your healthcare provider.
How long does it take to work?
Zolmitriptan usually starts to relieve migraine symptoms within 2 hours. Inform your doctor if your symptoms do not improve or if they worsen.
What should I do if a dose is missed?
Since Zolmitriptan is taken as needed, there is no regular dosing schedule. Take it as soon as possible once the migraine symptoms appear.
Comprehensive Drug Guide
How Does ZOLMitriptan Work?
Zolmitriptan is a selective serotonin receptor agonist. It exerts its effect by binding with 5HT1B/1D receptors located on blood vessels in the brain, leading to vasoconstriction. This decreases the neurological inflammation associated with migraines.
What is ZOLMitriptan Used For?
FDA indications: Zolmitriptan is tasked with the treatment of acute migraine headaches in adults with or without an aura.
Offlabel uses: There is no significant offlabel use for Zolmitriptan, its primary focus is doing battle with migraines.
Common Dosages
Tablets: 2.5mg, 5mg
Nasal spray: 2.5mg, 5mg
Orally disintegrating tablets: 2.5mg, 5mg
Typical Dosing
FDA Approved Indications
- Migraines: Start with 2.5mg, can be increased to 5mg if necessary. The maximum recommended dose in 24 hours is 10 mg.
Who Shouldn't Take ZOLMitriptan?
- Those with a history of heart disease, stroke, or circulatory problems.
- Those with uncontrolled high blood pressure.
- Those with allergies to Zolmitriptan or any of its constituents.
- Pregnant women, unless the potential benefit justifies the risk to the fetus.
- People with hemiplegic or basilar migraines.
Advice From The Pharmacist
- Make sure you take this medication exactly as your healthcare provider instructs.
- Seek medical attention if you experience any symptoms of a stroke, such as vision changes or speech difficulty.
- Talk to your healthcare provider if you are pregnant, plan to get pregnant, or are breastfeeding.
- Contact your doctor right away if you use Zolmitriptan and have heart palpitations or abnormal heartbeats.
- Take this medication as soon as you notice the symptoms of a migraine to ensure the best possible relief.
Side Effects of ZOLMitriptan
Common Side Effects
- Drowsiness, weakness or fatigue
- Tingling or numbness, warm/cold sensations
- Neck, throat, or jaw pain
- Heart attack symptoms: chest pain or pressure, pain spreading to your jaw or shoulder, feeling heavy, sweating.
- High levels of serotonin in the body: hallucinations, fever, fast heart rate, muscle stiffness, loss of coordination.
Risks and Warnings of ZOLMitriptan
- Heart problems: This medication can cause serious heart rhythm problems, heart attack, or stroke. Don't use it if you have a history of these conditions.
- Blood Pressure: Zolmitriptan can increase blood pressure. It's advisable to monitor your blood pressure while taking this medication.
- Liver function: Zolmitriptan is processed by the liver, hence may cause problems for people with liver disease.
- Medication overuse: Taking Zolmitriptan more than 10 days a month may increase the risk of getting more headaches.
Interactions with ZOLMitriptan
Common Drug Interactions
- Other triptan medications
- Ergotaminecontaining or ergottype medications
- SSRI or SNRI antidepressants
- MAO Inhibitors
- St. John's Wort
Alternatives to ZOLMitriptan
- Sumatriptan
- Rizatriptan
- Eletriptan
- Naratriptan
- Almotriptan
