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Lidotran
Lidotran is a topical anesthetic patch that contains lidocaine, a local anesthetic used to relieve pain associated with postherpetic neuralgia (pain that occurs after shingles) and other localized pain conditions. Lidocaine works by blocking nerve signals in the body, reducing the sensation of pain in the affected area. Lidotran is applied directly to the skin over the painful area to provide targeted pain relief without the systemic effects of oral medications.
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Frequently Asked Questions
How long does it take for Lidotran to start working?
Lidotran typically begins to relieve pain within 30 minutes of application, with the effects lasting for the duration of use (up to 12 hours).
Can I use Lidotran with other pain medications?
Yes, Lidotran can be used alongside other pain medications, including oral pain relievers like acetaminophen or ibuprofen. However, always consult your healthcare provider before combining treatments to avoid any potential interactions.
What should I do if the patch falls off?
If the patch falls off before the 12-hour period is over, you can apply a new patch to the affected area. Ensure the skin is clean and dry before reapplying.
Can Lidotran be used for other types of pain besides postherpetic neuralgia?
While Lidotran is primarily approved for postherpetic neuralgia, it may be used off-label for other types of localized pain, such as back pain, arthritis pain, or muscle strains.
Is Lidotran safe for long-term use?
Lidotran can be used long-term for chronic pain conditions under the supervision of a healthcare provider. Regular monitoring for skin reactions or side effects is recommended to ensure safety.
Comprehensive Drug Guide
How Does Lidotran Work?
Lidocaine, the active ingredient in Lidotran, works by blocking voltage-gated sodium channels in the nerve cells, preventing the nerves from sending pain signals to the brain. This action numbs the area where the patch is applied, providing local pain relief without affecting the entire body. Lidocaine helps reduce discomfort from conditions like postherpetic neuralgia by reducing the abnormal nerve activity associated with chronic pain.
Common Dosages
- Apply up to 3 patches at once for up to 12 hours within a 24-hour period.
Typical Dosing
- The usual dose for adults is one to three patches applied to the painful area once daily for up to 12 hours. After 12 hours, the patch should be removed, and the skin should be left patch-free for at least 12 hours before applying a new patch.
- The patch can be cut to fit smaller areas of pain.
Typical Dosing
FDA Approved Indications
- Postherpetic neuralgia (PHN): Pain that persists after an outbreak of shingles
- Localized pain due to other conditions where pain is confined to specific areas (off-label use)
Who Shouldn't Take Lidotran?
- Known hypersensitivity or allergy to lidocaine or other amide-type local anesthetics.
- Severe liver disease, which may affect the body's ability to metabolize lidocaine.
Advice From The Pharmacist
- Apply Lidotran to clean, dry skin in the area where pain is present. Make sure the skin is intact and free of cuts, rashes, or irritation.
- Do not apply the patch to areas of the body with severe burns, open wounds, or irritated skin.
- Remove the patch after 12 hours and do not apply another patch for at least 12 hours. This "on/off" cycle helps prevent skin irritation and reduces the risk of lidocaine absorption into the bloodstream.
- Wash your hands after handling the patch to avoid getting lidocaine in your eyes or mouth.
- If you experience severe redness, swelling, or irritation at the site of application, discontinue use and contact your healthcare provider.
Side Effects of Lidotran
Common Side Effects
- Mild redness or irritation at the application site
- Burning or itching where the patch is applied
- Numbness in the area of application
Uncommon/Severe Side Effects
- Allergic reactions (rash, itching, swelling, dizziness, trouble breathing)
- Severe skin irritation or blistering at the application site
- Systemic toxicity (rare, but possible with overuse or improper application), which may present as confusion, drowsiness, or irregular heartbeat
Risks and Warnings of Lidotran
- Systemic Absorption: Prolonged use of multiple patches or improper application (e.g., applying the patch to broken skin or leaving it on for longer than 12 hours) can result in the systemic absorption of lidocaine, leading to side effects such as dizziness, drowsiness, or irregular heart rhythms.
- Skin Reactions: Lidotran may cause local skin reactions, including redness, irritation, or swelling. If the irritation is severe or persists, discontinue use and consult a healthcare provider.
- Use in Special Populations: Individuals with liver impairment should use Lidotran with caution, as they may be at higher risk of systemic side effects due to slower metabolism of lidocaine.
Interactions with Lidotran
Common Drug Interactions
- Class I antiarrhythmics (e.g., mexiletine): Combining Lidotran with other local anesthetics or medications that affect heart rhythm may increase the risk of side effects.
- Other topical medications: Applying multiple topical treatments to the same area may increase the risk of irritation or alter the absorption of lidocaine.
- Beta-blockers: These medications can reduce the metabolism of lidocaine and increase the risk of systemic side effects.
Alternatives to Lidotran
- Lidocaine cream or gel: For those who prefer a cream or gel formulation, topical lidocaine products are available over-the-counter or by prescription.
- Capsaicin cream: A non-prescription topical analgesic used to treat nerve pain and other localized pain conditions.
- Flector Patch (diclofenac patch): A non-steroidal anti-inflammatory drug (NSAID) patch used for localized pain relief due to injury or arthritis.
- Oral pain medications: Over-the-counter options like acetaminophen or ibuprofen can be used to manage pain if topical therapy is insufficient.
