You're not logged in. Please log in to earn stock or Bitcoin rewards on your prescription purchase.
Bi-Mix
Bi-Mix is an injectable medication used to treat erectile dysfunction (ED). It contains two active ingredients: papaverine, a vasodilator, and phentolamine, an alpha-adrenergic blocker. When injected into the penis, Bi-Mix causes the blood vessels to widen (dilate) and the smooth muscles to relax, increasing blood flow to the penis, which helps achieve and maintain an erection. Bi-Mix is typically used when oral ED medications (such as sildenafil or tadalafil) are not effective or suitable.
Rx. Enter your prescription
How would you like to get your prescription? Select an option
Pharmacy pickup
Select from 35,000 pharmacies
Free two-day delivery
Coming soon!
Find a pharmacy near you. Enter your ZIP code
Are you a member? Sign up or log in.
Members have saved
$NaN
using our savings card for instant savings.
Don't pay full retail price and miss out on potential savings. Try it now—you have nothing to lose!
NaNM
worth of Satoshi has been rewarded to our members.
Everyone who signs up enjoys the benefits of earning FREE Bitcoin with every purchase.
How much Bitcoin can you earn with Bi-Mix ?
The potential for Bitcoin rewards to increase and appreciate in value is a possibility to consider, which may occur over time.
See the value of your savings today
Today's Value
1 Bitcoin = $NaN
Bitcoin (BTC)
...
USD
$NaN
Adjust Bitcoin's potential value to see how much it could be worth
Potential Value
1 Bitcoin =
Bitcoin (BTC)
...
USD
$NaN
Frequently Asked Questions
How long does it take for Bi-Mix to start working?
Bi-Mix typically starts working within 5 to 15 minutes after injection, with effects lasting about 30 to 60 minutes.
Can I adjust the dose of Bi-Mix on my own?
No, you should not adjust the dose of Bi-Mix without consulting your healthcare provider. Dose adjustments should be done carefully under medical supervision to avoid side effects like priapism.
Is it safe to use Bi-Mix with other ED treatments?
Using Bi-Mix with other ED treatments, especially oral medications, is not generally recommended due to the increased risk of side effects such as priapism. Always consult your healthcare provider before combining treatments.
What should I do if I experience a prolonged erection?
If you experience an erection lasting more than 4 hours, seek immediate medical attention. Priapism is a medical emergency that can cause permanent damage if not treated promptly.
Can Bi-Mix be stored at room temperature?
Bi-Mix is typically stored in the refrigerator, but specific storage instructions should be followed as provided by your compounding pharmacy. Do not freeze the medication, and protect it from light.
Comprehensive Drug Guide
How Does Bi-Mix Work?
- Papaverine: Inhibits phosphodiesterase enzymes, leading to an increase in cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP), which cause smooth muscle relaxation and vasodilation.
- Phentolamine: Blocks alpha-adrenergic receptors, preventing norepinephrine from constricting blood vessels, which also contributes to vasodilation and increased blood flow.
Common Dosages
The typical dosage of Bi-Mix varies depending on the individual patient's response and the severity of ED. The dose is usually determined by a healthcare provider and may require adjustment based on efficacy and tolerance.
- Starting Dose: The initial dose may be low to assess tolerance, usually around 0.1 to 0.3 mL, and is adjusted as needed.
- Maintenance Dose: The dose may be adjusted in small increments to achieve the desired effect, usually within the range of 0.1 to 0.5 mL per injection.
Typical Dosing
- Administration: Bi-Mix is administered via intracavernosal injection directly into the side of the penis. The injection should be performed using a fine needle, and it is important to rotate the injection site to avoid tissue damage. Patients are typically trained by a healthcare provider on how to properly inject the medication.
- Timing: The medication is usually injected 5 to 15 minutes before sexual activity. The effects can last for about 30 to 60 minutes, but the duration can vary depending on the dose and individual response.
Typical Dosing
FDA Approved Indications
Treatment of Erectile Dysfunction (ED): Particularly in men who do not respond to or cannot take oral ED medications.
Who Shouldn't Take Bi-Mix?
- Known hypersensitivity to papaverine, phentolamine, or any component of the injection.
- Conditions predisposing them to priapism (prolonged erection), such as sickle cell anemia, leukemia, or multiple myeloma.
- Penile implants or anatomical deformities of the penis (e.g., Peyronie’s disease).
Advice From The Pharmacist
- Follow the injection instructions carefully as provided by their healthcare provider, and never adjust the dose without medical advice.
- Rotate injection sites to minimize the risk of scarring or tissue damage.
- Store the medication as directed, typically in a refrigerator, and protect it from light.
- Report any prolonged erections lasting more than 4 hours (priapism) to a healthcare provider immediately, as this is a medical emergency.
- Avoid using alcohol or recreational drugs, which can interfere with the effectiveness of the medication.
Side Effects of Bi-Mix
Common Side Effects
- Pain or discomfort at the injection site
- Bruising or swelling at the injection site
- Mild bleeding after the injection
Uncommon/Severe Side Effects
- Priapism: A prolonged erection lasting more than 4 hours, which can cause permanent damage to the penis if not treated promptly.
- Penile Fibrosis: Scarring or thickening of the penile tissue, which can occur with repeated injections.
- Dizziness or Low Blood Pressure: Due to the vasodilatory effects of the medication.
Patients should seek immediate medical attention if they experience signs of priapism or any severe or persistent side effects.
Risks and Warnings of Bi-Mix
- Priapism: The most significant risk with Bi-Mix is priapism, a condition in which an erection lasts for more than 4 hours. This condition requires immediate medical attention to prevent long-term damage.
- Injection Site Reactions: Repeated injections in the same area can cause tissue damage, scarring, or fibrosis. Patients should rotate injection sites and report any lumps or abnormalities to their healthcare provider.
- Blood Pressure Effects: Bi-Mix can cause a drop in blood pressure, especially when combined with other blood pressure-lowering medications or alcohol.
Interactions with Bi-Mix
Common Drug Interactions
- Blood Pressure Medications: Such as antihypertensives or nitrates, which can increase the risk of low blood pressure.
- Other ED Medications: Combining Bi-Mix with other ED treatments like sildenafil (Viagra) or tadalafil (Cialis) can increase the risk of priapism or other side effects.
Patients should inform their healthcare provider of all medications and supplements they are taking to avoid potential interactions.
Alternatives to Bi-Mix
- Oral Medications: Such as sildenafil (Viagra), tadalafil (Cialis), or vardenafil (Levitra).
- Other Injectable Medications: Such as Trimix, which combines three medications (papaverine, phentolamine, and alprostadil) for a more potent effect.
- Vacuum Erection Devices (VEDs): Non-pharmacological options that use a vacuum pump to draw blood into the penis.
- Penile Implants: A surgical option for men who do not respond to other treatments.
The choice of treatment depends on the patient’s specific condition, response to previous treatments, and overall health.
