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Vardenafil HCl

Vardenafil belongs to a class of drugs called phosphodiesterase type-5 (PDE5) inhibitors. The medication is used for treating erectile dysfunction, improving men's ability to maintain an erection during sexual activity. Some common side effects can include a headache, flushing, or a stuffy nose.

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Frequently Asked Questions

Can I take vardenafil if I have heart disease?
Open FAQClose FAQ

You should always consult with your healthcare provider. They will assess your heart function and determine if your heart is healthy enough for sex.

Does vardenafil cause headaches?
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Yes, headaches are a common side effect. Drinking a lot of water can often help reduce the headache.

I missed a dose of vardenafil, what should I do?
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This medication is taken as needed, so you're unlikely to miss a dose.

Can I just stop taking vardenafil?
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As it's taken as needed, there's no requirement to take it continuously, so you can stop its usage without any issues.

Will vardenafil improve my libido?
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No, vardenafil doesn't have an effect on sexual desire. It can help you achieve and maintain an erection, but it doesn't create sexual arousal.

Can I have a glass of wine while on vardenafil?
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Alcohol is not recommended as it can increase the medication side effects like dizziness and affect your ability to achieve an erection.

Comprehensive Drug Guide

How Does Vardenafil HCl Work?

Vardenafil is a PDE5 inhibitor, it helps to increase the blood flow in the penis by stopping the enzyme PDE5 from breaking down cyclic guanosine monophosphate (cGMP). This chemical reaction causes the penis to remain erect for longer duration, aiding in sexual intercourse.

Common Dosages

Common Dosages

  • Tablets: 2.5mg, 5mg, 10mg, 20mg
  • Orally disintegrating tablet: 10mg

Typical Dosing

  • For erectile dysfunction: The starting dose is 10 mg. It is taken one hour before sexual activity. Depending on efficacy and side effects, the dose may be increased to 20 mg or reduced to 5 mg.


Typical Dosing

FDA Approved Indications

FDA indications: Vardenafil is used to treat erectile dysfunction.

Off-Label Uses

It's also occasionally used for the treatment of benign prostatic hyperplasia, pulmonary hypertension, and secondary raynauds phenomenon

Who Shouldn't Take Vardenafil HCl?

  • Have hypersensitivity to vardenafil.
  • Use nitrate drugs in any form, due to increased hypotension risk.
  • Are taking drugs known as "poppers" (such as amyl nitrate, butyl nitrate).
  • Have been advised against sexual activity due to certain health factors.
  • Have severe liver or kidney disease.
  • Have recently had a heart attack or stroke.
  • Have certain types of eye problems like retinitis pigmentosa.


Advice From The Pharmacist

  • Always take as directed by your healthcare provider, typically 60 minutes before sexual activity.
  • You can take with or without food
  • Do not take more than one dose a day.
  • Inform your doctor of all medications, including over-the-counter drugs and supplements, to ensure drug interactions are assessed.
  • If you experience a sudden and severe decrease or loss of vision or hearing, stop taking it and seek immediate medical attention.
  • Avoid alcohol, it may increase side effects likeliness such as headaches, dizziness, or changes in heart rate.


Side Effects of Vardenafil HCl

Common Side Effects

  • Headaches, flushing, and stuffy or runny nose are some of the most commonly reported side effects.
  • You may also feel an upset stomach or dizziness.


Uncommon/Severe Side Effects

  • If you experience any changes in your hearing or vision, seek medical help right away.
  • In an event of an erection lasting for more than 4 hours (priapism), seek immediate medical attention.


Risks and Warnings of Vardenafil HCl

  • If you're on any medication for heart problems, discuss with your healthcare provider before you start Vardenafil. This drug can cause a serious drop in your blood pressure leading to dizziness, fainting, or rarely heart attack, or stroke. 
  • Should you experience an erection lasting longer than 4 hours, stop using this drug and seek immediate medical attention.


Interactions with Vardenafil HCl

Common Drug Interactions

  • Alpha-blockers (such as Prazosin and Tamsulosin)
  • Antifungals
  • HIV protease inhibitors
  • Some antiarrhythmics
  • Some antibiotics
  • Grapefruit Juice


Common Food Interactions

  • Grapefruit products should be avoided.
  • Alcohol can increase side effects.


Alternatives to Vardenafil HCl

  • Sildenafil (Viagra)
  • Tadalafil (Cialis)
  • Avanafil (Stendra)