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Viagra
Viagra (generic name: sildenafil) is a medication used to treat erectile dysfunction (ED) in men. It belongs to the class of drugs known as phosphodiesterase type 5 (PDE5) inhibitors, which work by increasing blood flow to the penis to help a man achieve and maintain an erection during sexual activity. Viagra does not increase sexual desire but works in response to sexual stimulation. It is a well-known brand name medication that has been widely prescribed for the treatment of ED since its approval.
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Frequently Asked Questions
How long does Viagra last?
Viagra typically lasts for up to 4-5 hours, allowing time for sexual activity. However, this doesn't mean you'll have an erection for the entire duration, but rather that you can achieve an erection when sexually stimulated during this time.
Can I take Viagra with food?
Yes, Viagra can be taken with or without food. However, a high-fat meal may slow down the time it takes for the medication to start working.
Is it safe to take Viagra every day?
You should only take Viagra as prescribed by your doctor. For most men, it is not necessary to take it every day. If you require frequent dosing, your doctor may suggest other treatments.
Can women take Viagra?
Viagra is not approved for use in women. However, some studies are exploring its potential for treating sexual dysfunction in women. Speak to your healthcare provider for more information.
What happens if I take too much Viagra?
Taking more than the prescribed dose of Viagra can increase the risk of severe side effects such as prolonged erections (priapism), low blood pressure, or fainting. Always follow your doctor's instructions for safe use.
Comprehensive Drug Guide
How Does Viagra Work?
Viagra works by inhibiting the enzyme PDE5, which is responsible for the breakdown of cyclic guanosine monophosphate (cGMP). cGMP regulates blood flow in the penis, and its increased levels lead to the relaxation of smooth muscle in the blood vessels, allowing for enhanced blood flow. This results in an erection in response to sexual stimulation.
Common Dosages
- 25 mg, 50 mg, and 100 mg oral tablets.
The recommended starting dose is usually 50 mg, but this can be adjusted based on effectiveness and tolerance.
Typical Dosing
- For erectile dysfunction: The typical dose is 50 mg taken approximately 1 hour before sexual activity. Depending on the individual’s response, the dose may be increased to 100 mg or decreased to 25 mg. Viagra can be taken anywhere from 30 minutes to 4 hours before sexual activity.
- Do not take more than one dose in a 24-hour period.
Typical Dosing
FDA Approved Indications
- Erectile Dysfunction (ED)
Off-label, sildenafil (the active ingredient in Viagra) may also be used for pulmonary arterial hypertension (PAH) under the brand name Revatio.
Who Shouldn't Take Viagra?
- Severe cardiovascular disorders, such as unstable angina or recent heart attack.
- Use of nitrate medications for chest pain, as the combination can lead to a dangerous drop in blood pressure.
- Known hypersensitivity or allergic reaction to sildenafil or any of its components.
Advice From The Pharmacist
- Take Viagra as directed, approximately 30-60 minutes before sexual activity. It can be taken with or without food, but a high-fat meal may delay its effect.
- Avoid drinking excessive amounts of alcohol, as this can reduce the effectiveness of Viagra.
- If you experience an erection lasting more than 4 hours (priapism), seek medical attention immediately, as this can cause long-term damage.
- Viagra does not protect against sexually transmitted infections (STIs), including HIV, so be sure to practice safe sex.
Side Effects of Viagra
Common Side Effects
- Headache
- Flushing
- Upset stomach or indigestion
- Nasal congestion
- Dizziness
Uncommon/Severe Side Effects
- Sudden vision loss or hearing loss
- Chest pain or irregular heartbeat
- Shortness of breath
- Severe allergic reactions (rash, swelling, difficulty breathing)
Risks and Warnings of Viagra
- Cardiovascular Risk: Viagra can cause a sudden drop in blood pressure, especially when used with nitrates. This can lead to fainting, dizziness, or even a heart attack in individuals with pre-existing heart conditions.
- Vision and Hearing Loss: Some people may experience sudden vision or hearing loss after taking Viagra. Seek immediate medical attention if this occurs.
- Priapism: Prolonged erections lasting more than 4 hours can cause permanent damage to the penis. Seek emergency medical help if this occurs.
Interactions with Viagra
Common Drug Interactions
- Nitrates (e.g., nitroglycerin): Combining Viagra with nitrates can lead to a dangerous drop in blood pressure.
- Alpha-blockers: These medications, used to treat high blood pressure or prostate conditions, can also lower blood pressure, and their use with Viagra may lead to hypotension.
- CYP3A4 inhibitors: Drugs like ketoconazole or ritonavir can increase the levels of Viagra in the bloodstream, increasing the risk of side effects.
- Alcohol: Drinking large amounts of alcohol while using Viagra can reduce its effectiveness and increase the risk of side effects such as dizziness.
Alternatives to Viagra
- Cialis (tadalafil): Another PDE5 inhibitor, known for its longer duration of action (up to 36 hours).
- Levitra (vardenafil): Similar to Viagra, but may work better for some individuals based on personal response.
- Stendra (avanafil): A newer PDE5 inhibitor that acts faster than Viagra.
- Alprostadil: An injectable or suppository form of ED treatment that directly stimulates an erection.
