Adzenys XR-ODT

Adzenys XR-ODT is FDA-approved for the treatment of Attention-Deficit/Hyperactivity Disorder (ADHD) in patients aged 6 years and older. It is intended to help manage symptoms such as inattention, hyperactivity, and impulsivity, which can interfere with daily functioning in both children and adults.

There are no widely recognized off-label uses for Adzenys XR-ODT, as its primary indication is for ADHD.

Adzenys XR-ODT should not be used in individuals who have:

• A known hypersensitivity or allergic reaction to amphetamine or any other components of the medication.
• A history of cardiovascular conditions, such as heart disease, high blood pressure, or arrhythmias.
• Hyperthyroidism (overactive thyroid).
• Glaucoma.
• A history of drug abuse or dependence.
• Are currently taking or have recently taken monoamine oxidase inhibitors (MAOIs).

It is important to discuss your full medical history with your healthcare provider before starting this medication.

When taking Adzenys XR-ODT, it is important to take it exactly as prescribed by your healthcare provider. Avoid taking it in the afternoon or evening, as it can cause difficulty sleeping (insomnia). The medication should dissolve on the tongue and be swallowed with saliva—no water is needed. Keep the medication in its original packaging until ready to use, as it is sensitive to moisture. Avoid consuming alcohol or caffeine while on this medication, as they can increase side effects like jitteriness or anxiety. If you notice any unusual side effects or have concerns about the medication, contact your healthcare provider.

Common side effects of Adzenys XR-ODT include loss of appetite, difficulty sleeping, dry mouth, irritability, nervousness, and increased heart rate. These side effects are usually mild and may decrease over time. More serious side effects, though less common, include increased blood pressure, heart palpitations, signs of allergic reactions (e.g., rash, swelling, difficulty breathing), and changes in mood or behavior (e.g., aggression, hallucinations). If you experience any of these serious symptoms, seek medical attention immediately.

The major risks associated with Adzenys XR-ODT include the potential for cardiovascular issues, such as increased blood pressure and heart rate, as well as the risk of abuse, dependence, and misuse due to its stimulant properties. Patients with a history of heart problems or substance abuse should use this medication with caution. Long-term use can also potentially lead to growth suppression in children, so regular monitoring by a healthcare provider is essential. Additionally, stopping the medication abruptly after prolonged use can lead to withdrawal symptoms.

Adzenys XR-ODT can interact with other medications, including:

• Monoamine oxidase inhibitors (MAOIs): Can cause dangerous increases in blood pressure and should not be used with Adzenys XR-ODT.
• Other stimulant medications: Can increase the risk of side effects like increased heart rate and blood pressure.
• Certain antidepressants: Can affect the way Adzenys XR-ODT works and increase the risk of side effects.
• Antacids: Can alter the absorption of the medication and affect its effectiveness.

Always inform your healthcare provider of all medications, supplements, and herbal products you are taking to avoid potential interactions.

Alternative medications for managing ADHD include other stimulant medications such as:

• Vyvanse (lisdexamfetamine)
• Concerta (methylphenidate)
• Ritalin (methylphenidate)

Non-stimulant medications like Strattera (atomoxetine) and Intuniv (guanfacine) may also be considered, depending on the patient's needs and response to treatment. Your healthcare provider can help determine the best treatment option based on your specific situation.