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Concerta

Concerta (methylphenidate HCl) is a central nervous system (CNS) stimulant used to treat attention deficit hyperactivity disorder (ADHD) in children, adolescents, and adults. It helps improve focus, attention, and impulse control by increasing levels of dopamine and norepinephrine in the brain.



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Frequently Asked Questions

How long does it take for Concerta to start working?
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Concerta typically starts working within 1 hour of taking the dose, and the effects last up to 12 hours.

Can Concerta cause weight loss?
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Yes, Concerta can suppress appetite, which may lead to weight loss, especially in children and adolescents.

Can I stop taking Concerta abruptly?
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It’s generally safe to stop Concerta without tapering, but it’s best to consult your healthcare provider, as stopping it abruptly may result in withdrawal symptoms, such as fatigue or depression.

Can I take Concerta with other medications?
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Concerta can interact with several medications, including MAO inhibitors and antihypertensives. Inform your healthcare provider about all medications and supplements you are taking.

Is Concerta addictive?
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Concerta has a high potential for abuse and dependence, especially if not taken as prescribed. Misuse of Concerta can lead to addiction and serious health problems.

Comprehensive Drug Guide

How Does Concerta Work?

Concerta works by blocking the reuptake of dopamine and norepinephrine in the brain, which increases the availability of these neurotransmitters. This action helps improve attention span, focus, and impulse control in individuals with ADHD.



Common Dosages

  • Extended-release tablets: 18 mg, 27 mg, 36 mg, 54 mg

Typical Dosing

  • For ADHD: The starting dose is 18 mg once daily in the morning, which may be adjusted based on response and tolerance. The maximum daily dose is 72 mg.


Typical Dosing

FDA Approved Indications

  • Attention Deficit Hyperactivity Disorder (ADHD) in children aged 6 years and older, adolescents, and adults.


Who Shouldn't Take Concerta?

  • Known hypersensitivity to methylphenidate or any component of the formulation.
  • Glaucoma
  • Severe anxiety or agitation
  • History of tics or Tourette’s syndrome


Advice From The Pharmacist

  • Take Concerta once daily in the morning, as taking it later in the day can cause insomnia.
  • Swallow the tablet whole; do not crush, chew, or break it, as this can release too much medication at once.
  • Concerta is a long-acting medication, so you should experience symptom control throughout the day.
  • Avoid consuming large amounts of caffeine while taking Concerta, as it can increase stimulant effects and side effects like anxiety and nervousness.


Side Effects of Concerta

Common Side Effects

  • Loss of appetite
  • Insomnia
  • Headache
  • Dry mouth
  • Nervousness


Uncommon/Severe Side Effects

  • Heart problems, such as increased heart rate or blood pressure
  • Psychiatric problems, including new or worsening aggression, hostility, or mania
  • Growth suppression in children with long-term use


Risks and Warnings of Concerta

  • Cardiovascular Risk: Stimulants like Concerta can increase heart rate and blood pressure. Individuals with pre-existing heart conditions should use Concerta with caution and under close medical supervision.
  • Abuse Potential: Concerta is a Schedule II controlled substance, meaning it has a high potential for abuse and dependence. Misuse of Concerta can lead to serious health risks, including heart problems and addiction.
  • Psychiatric Effects: Concerta may cause or worsen psychiatric symptoms, including anxiety, depression, and mania, particularly in individuals with a history of mental health disorders.


Interactions with Concerta

Common Drug Interactions

  • Monoamine oxidase inhibitors (MAOIs): Taking Concerta with MAOIs can result in a dangerous interaction, leading to a hypertensive crisis.
  • Antihypertensive medications: Concerta may reduce the effectiveness of blood pressure medications, increasing the risk of elevated blood pressure.
  • Alcohol: Alcohol can increase the release of methylphenidate from the extended-release formulation, leading to a higher risk of side effects.


Alternatives to Concerta

  • Adderall XR (amphetamine/dextroamphetamine): A stimulant medication also used to treat ADHD, available in extended-release form.
  • Vyvanse (lisdexamfetamine): A stimulant medication used to treat ADHD, with less potential for abuse due to its prodrug formulation.
  • Strattera (atomoxetine): A non-stimulant medication used for the treatment of ADHD.