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Strattera
Strattera (generic name: atomoxetine) is a non-stimulant medication used to treat Attention-Deficit/Hyperactivity Disorder (ADHD) in both children and adults. Unlike stimulant medications such as Adderall or Ritalin, Strattera is a selective norepinephrine reuptake inhibitor (NRI), which helps increase the levels of norepinephrine in the brain, improving attention span, focus, and impulse control. Strattera is often chosen for individuals who cannot tolerate stimulant medications or are at risk for misuse.
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Frequently Asked Questions
How long does it take for Strattera to start working?
Strattera may take 2 to 4 weeks to notice significant improvements in ADHD symptoms. Full effects may take up to 6 weeks.
Is Strattera a stimulant?
No, Strattera is a non-stimulant medication for ADHD, which makes it a good option for individuals who do not respond well to or cannot tolerate stimulant medications.
Can I take Strattera with other ADHD medications?
In some cases, Strattera may be combined with other ADHD medications, such as stimulants, to optimize treatment. However, this should only be done under the guidance of a healthcare provider.
Does Strattera cause weight loss?
Some patients may experience decreased appetite or mild weight loss when starting Strattera, but this is generally not as pronounced as with stimulant medications.
Can Strattera be used for adults with ADHD?
Yes, Strattera is approved for the treatment of ADHD in both children and adults. Adults may start at a lower dose, which is gradually increased based on the response to the medication.
Comprehensive Drug Guide
How Does Strattera Work?
Strattera works by selectively inhibiting the reuptake of norepinephrine, a neurotransmitter involved in regulating attention, focus, and behavior. By increasing norepinephrine levels in the brain, Strattera helps to improve attention and reduce impulsivity and hyperactivity in individuals with ADHD.
Common Dosages
- 10 mg, 18 mg, 25 mg, 40 mg, 60 mg, 80 mg, and 100 mg
Typical Dosing
- The typical starting dose for Strattera in children and adolescents is 0.5 mg/kg/day, which may be increased after a few days based on response. The maximum dose is 1.4 mg/kg/day or 100 mg/day, whichever is lower.
- For adults, the starting dose is typically 40 mg per day, which may be increased to 80 mg per day after 3 days, with a maximum dose of 100 mg per day.
Strattera is usually taken once or twice daily, with or without food.
Typical Dosing
FDA Approved Indications
- Attention-Deficit/Hyperactivity Disorder (ADHD) in children, adolescents, and adults.
Who Shouldn't Take Strattera?
- Narrow-angle glaucoma
- Severe cardiovascular conditions, such as serious heart problems or high blood pressure
- MAOI use within the past 14 days (due to the risk of serious interactions)
Advice From The Pharmacist
- Strattera can be taken with or without food. If it causes stomach upset, taking it with food may help.
- It is important to take Strattera regularly as prescribed to see full benefits, as it may take several weeks to notice improvements in ADHD symptoms.
- Do not break or open Strattera capsules, as the medication inside can irritate the eyes or skin.
- Avoid using alcohol or other central nervous system depressants while taking Strattera, as this can worsen drowsiness or dizziness.
Side Effects of Strattera
Common Side Effects
- Dry mouth
- Nausea
- Decreased appetite
- Fatigue or drowsiness
- Dizziness
- Insomnia
Uncommon/Severe Side Effects
- Increased blood pressure or heart rate
- Liver damage, indicated by symptoms like dark urine, yellowing of the skin or eyes, or unexplained fatigue.
- Suicidal thoughts in children and adolescents (although rare, patients should be monitored for mood changes).
Risks and Warnings of Strattera
- Suicide Risk: Strattera has been associated with an increased risk of suicidal thoughts in children and adolescents. Caregivers and healthcare providers should closely monitor patients for any mood changes, depression, or unusual behavior.
- Cardiovascular Risk: Strattera can increase heart rate and blood pressure. Patients with a history of cardiovascular disease, arrhythmias, or hypertension should use Strattera with caution and be regularly monitored.
- Liver Damage: Rare cases of liver damage have been reported in patients taking Strattera. If you experience symptoms such as dark urine, jaundice, or unexplained fatigue, contact your healthcare provider immediately.
Interactions with Strattera
Common Drug Interactions
- MAO Inhibitors: Strattera should not be used with MAO inhibitors (such as phenelzine or tranylcypromine) due to the risk of serious interactions.
- Blood pressure medications: Strattera may interact with antihypertensive medications, potentially reducing their effectiveness or causing an increase in blood pressure.
- Albuterol: Caution should be exercised when using Strattera with high doses of albuterol (a common asthma medication), as it may increase heart rate or blood pressure.
Alternatives to Strattera
- Stimulants: Medications like Adderall (amphetamine) or Ritalin (methylphenidate) are commonly used first-line treatments for ADHD, but they are controlled substances with potential for misuse.
- Guanfacine (Intuniv): A non-stimulant medication used to treat ADHD, particularly in children.
- Clonidine (Kapvay): Another non-stimulant medication used to treat ADHD, often for patients with additional sleep difficulties.
