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Adhansia XR

Adhansia XR is an extended-release formulation of methylphenidate, a central nervous system (CNS) stimulant used to treat attention-deficit hyperactivity disorder (ADHD) in children and adults. Methylphenidate works by increasing levels of dopamine and norepinephrine in the brain, which helps improve focus, attention, and impulse control. Adhansia XR provides long-lasting effects, making it a convenient once-daily treatment option for managing ADHD symptoms throughout the day.


Adhansia XR is available by prescription only and comes in extended-release capsules of varying strengths. It is classified as a Schedule II controlled substance due to its potential for abuse and dependence. Patients prescribed Adhansia XR should be closely monitored by their healthcare provider, and the medication should be used exactly as directed.


Adhansia XR belongs to the formal drug class of central nervous system (CNS) stimulants. Informally, it may be referred to as an ADHD medication or a stimulant. These classifications relate to its purpose in enhancing focus, attention, and impulse control in individuals with ADHD.



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Frequently Asked Questions

How long does it take for Adhansia XR to start working?
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Adhansia XR typically begins to work within 1-2 hours after taking the dose, with effects lasting throughout the day due to its extended-release formulation.

Can Adhansia XR be taken with food?
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Yes, Adhansia XR can be taken with or without food. However, taking it with food may help reduce stomach discomfort.

What should I do if I miss a dose of Adhansia XR?
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If you miss a dose, take it as soon as you remember, but avoid taking it late in the day to prevent sleep disturbances. If it is close to the next scheduled dose, skip the missed dose and continue with your regular schedule.

Can Adhansia XR be used in children?
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Yes, Adhansia XR is approved for use in children aged 6 years and older. The dosage will be carefully adjusted based on the child’s response and tolerance.

Are there any dietary restrictions while taking Adhansia XR?
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There are no specific dietary restrictions, but it is important to maintain a healthy diet, as Adhansia XR can reduce appetite, potentially affecting growth in children.

Comprehensive Drug Guide

How Does Adhansia XR Work?

Adhansia XR works by inhibiting the reuptake of dopamine and norepinephrine in the brain, which increases their availability in the synaptic cleft. These neurotransmitters play key roles in regulating attention, behavior, and mood. By enhancing their activity, Adhansia XR helps improve the symptoms of ADHD, such as inattention, hyperactivity, and impulsivity. The extended-release formulation ensures a gradual release of the medication throughout the day, providing sustained symptom control.



Common Dosages

Adhansia XR is available in a range of strengths, including:

  • 25 mg
  • 35 mg
  • 45 mg
  • 55 mg
  • 70 mg
  • 85 mg

The appropriate dosage is determined based on the patient’s age, weight, and response to treatment, with regular adjustments as necessary.


The typical dosing for Adhansia XR involves taking one capsule orally once daily in the morning, with or without food. The dosage is usually started at a lower level and gradually increased based on the patient’s response and tolerance. It is important to take the medication at the same time each day and avoid taking it in the afternoon or evening to prevent insomnia.





Typical Dosing

FDA Approved Indications

Adhansia XR is FDA-approved for the treatment of attention-deficit hyperactivity disorder (ADHD) in patients aged 6 years and older. It is designed to be used as part of a comprehensive treatment plan that includes psychological, educational, and social measures.



Off-Label Uses

Off-label uses of methylphenidate may include treatment of narcolepsy, but these should be discussed with a healthcare provider.



Who Shouldn't Take Adhansia XR?

Adhansia XR should not be used in individuals who:

  • Have a known hypersensitivity to methylphenidate or any of the components in the formulation
  • Have marked anxiety, tension, or agitation
  • Have a history of glaucoma
  • Have a history of tics or Tourette’s syndrome
  • Have severe hypertension or cardiovascular conditions

It is also contraindicated in patients currently taking monoamine oxidase inhibitors (MAOIs) or within 14 days of stopping such treatment.



Advice From The Pharmacist

When taking Adhansia XR, it is important to follow the prescribed dosing schedule closely and not to crush, chew, or open the capsules, as this can affect the extended-release properties. Be aware of potential side effects, including increased heart rate and blood pressure, and inform your healthcare provider if you experience any unusual symptoms. Regular follow-ups are essential to monitor the effectiveness of the medication and to make any necessary dosage adjustments. If a dose is missed, take it as soon as you remember, but avoid taking it late in the day to prevent sleep disturbances.



Side Effects of Adhansia XR

Common Side Effects

Common side effects of Adhansia XR may include:

  • Decreased appetite
  • Insomnia
  • Dry mouth
  • Headache
  • Anxiety
  • Stomach pain
  • Increased heart rate


Uncommon/Severe Side Effects

Serious side effects, though rare, may include:

  • Chest pain
  • Shortness of breath
  • Severe hypertension
  • Hallucinations or psychotic symptoms
  • Seizures

If any serious side effects occur, seek medical attention immediately.



Risks and Warnings of Adhansia XR

The major risks associated with Adhansia XR include the potential for abuse, dependence, and cardiovascular complications. Because it is a CNS stimulant, there is a risk of increased heart rate, blood pressure, and potential heart problems, especially in patients with preexisting cardiovascular conditions. It is important to use Adhansia XR only as prescribed and to keep it out of reach of others, particularly those with a history of substance abuse. Regular monitoring by a healthcare provider is essential to manage these risks effectively.



Interactions with Adhansia XR

Common Drug Interactions

Adhansia XR can interact with several medications, including:

  • Monoamine oxidase inhibitors (MAOIs)
  • Antihypertensive medications
  • Antipsychotics
  • Tricyclic antidepressants
  • Blood thinners (e.g., warfarin)

These interactions can increase the risk of side effects or reduce the effectiveness of the medication. It is important to inform your healthcare provider of all medications, supplements, and over-the-counter products you are taking to avoid potential interactions.



Alternatives to Adhansia XR

Alternative treatments for ADHD include other stimulant medications such as Adderall (amphetamine salts), Vyvanse (lisdexamfetamine), and Concerta (another extended-release form of methylphenidate). Non-stimulant options like Strattera (atomoxetine) and Intuniv (guanfacine) may also be considered, depending on the patient’s needs and response to treatment. Behavioral therapies and lifestyle interventions should also be part of the overall treatment plan.