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Zyclara Pump
Zyclara Pump (imiquimod) is a topical immune response modifier used to treat actinic keratosis (AK), a precancerous skin condition caused by excessive sun exposure. It is also used for the treatment of external genital and perianal warts. Zyclara works by stimulating the body’s immune system to fight abnormal skin cells or viral infections, helping to clear affected areas. The pump formulation allows for easy application of the cream in precise amounts.
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Frequently Asked Questions
How long does it take for Zyclara Pump to work?
For actinic keratosis, improvement can typically be seen within 2-4 weeks. For genital warts, it may take up to 8 weeks of daily treatment to see the full results.
Can I use Zyclara Pump on other parts of the body?
Zyclara Pump is approved for use on the face, scalp, and genital areas. It should not be applied to mucous membranes or used on open sores or broken skin unless directed by your healthcare provider.
How should I store Zyclara Pump?
Store Zyclara Pump at room temperature away from direct sunlight and moisture. Keep the pump tightly closed when not in use.
What should I do if I miss a dose of Zyclara Pump?
If you miss a dose, apply it as soon as you remember. If it is close to the time of your next scheduled dose, skip the missed dose and resume your normal dosing schedule. Do not double up on doses.
Can Zyclara Pump be used during pregnancy?
Zyclara should only be used during pregnancy if clearly needed and prescribed by a healthcare provider. Discuss potential risks and benefits with your doctor before starting treatment.
Comprehensive Drug Guide
How Does Zyclara Pump Work?
Zyclara Pump works by activating the body’s immune system, specifically by inducing the production of cytokines such as interferon-alpha. These cytokines help boost the immune response, which targets abnormal or infected cells in the skin, leading to the destruction of actinic keratosis lesions or warts caused by human papillomavirus (HPV).
Common Dosages
- For actinic keratosis: Apply once daily for 2 weeks, followed by a 2-week rest period, and repeat for an additional 2 weeks if needed.
- For external genital warts: Apply once daily until the warts are gone, for up to 8 weeks.
Typical Dosing
- For actinic keratosis: Apply one pumpful of cream to the affected area once daily before bedtime. Continue for two weeks, followed by a two-week rest, and then repeat if necessary.
- For external genital warts: Apply one pumpful to the affected area once daily at bedtime until the warts disappear, for a maximum duration of 8 weeks.
Typical Dosing
FDA Approved Indications
- Actinic keratosis (AK) on the face and scalp in adults
- External genital and perianal warts (condyloma acuminatum) in patients aged 12 years and older
Who Shouldn't Take Zyclara Pump?
- Known hypersensitivity to imiquimod or any component of the formulation.
- Broken or infected skin where treatment is not intended.
Advice From The Pharmacist
- Zyclara Pump should be applied once daily at bedtime and washed off in the morning with mild soap and water.
- Avoid applying the cream to broken or irritated skin, and ensure that the treated area is completely dry before applying the medication.
- Store Zyclara Pump at room temperature and avoid exposure to direct sunlight or heat.
- Avoid covering the treated area with occlusive dressings or bandages unless instructed by a healthcare provider.
- Wash hands thoroughly after applying the cream to avoid spreading it to unintended areas.
Side Effects of Zyclara Pump
Common Side Effects
- Redness, itching, or burning at the application site
- Flaking or scaling of the skin
- Swelling or crusting of the treated area
Uncommon/Severe Side Effects
- Severe local skin reactions, such as intense redness, blistering, or ulceration
- Flu-like symptoms (fever, body aches, fatigue)
- Swelling of lymph nodes near the treated area
Risks and Warnings of Zyclara Pump
- Skin Reactions: Zyclara Pump may cause significant local skin reactions, including redness, itching, or swelling. These are usually signs that the medication is working, but if they become severe, discontinue use and contact your healthcare provider.
- Photosensitivity: Zyclara may increase sensitivity to sunlight, leading to a higher risk of sunburn. Use sunscreen and protective clothing, and avoid prolonged sun exposure during treatment.
- Flu-like Symptoms: Some patients may experience flu-like symptoms, including body aches and fatigue. These usually resolve when treatment is discontinued.
Interactions with Zyclara Pump
Common Drug Interactions
- There are no major systemic drug interactions with Zyclara Pump, as it is a topical medication. However, inform your healthcare provider if you are using other topical medications or have underlying conditions that could affect the use of Zyclara.
Alternatives to Zyclara Pump
- Aldara (imiquimod 5%): A similar topical cream used for actinic keratosis, genital warts, and superficial basal cell carcinoma.
- Fluorouracil (Efudex): A topical chemotherapy agent used for treating actinic keratosis and superficial skin cancers.
- Cryotherapy: A freezing technique used to treat actinic keratosis and genital warts.
