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Vtama
Vtama (generic name: tapinarof) is a topical cream used to treat plaque psoriasis in adults. It belongs to a new class of topical medications called aryl hydrocarbon receptor (AhR) agonists, which help reduce inflammation and regulate the immune response in the skin. Vtama is designed for once-daily application to areas affected by psoriasis, helping to reduce the appearance of plaques, scaling, and redness.
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Frequently Asked Questions
How long does it take for Vtama to work?
Vtama may start showing results within two to four weeks, but full improvement may take longer depending on the severity of your psoriasis. Continue using the cream as prescribed by your healthcare provider.
Can I use Vtama on my face?
Vtama is not typically used on sensitive areas like the face, groin, or underarms unless directed by your healthcare provider. Avoid applying it to these areas unless advised otherwise.
Is Vtama safe for long-term use?
Vtama is intended for long-term use under the guidance of a healthcare provider. Regular monitoring by your doctor is recommended to ensure its effectiveness and safety.
What should I do if I miss a dose of Vtama?
If you miss a dose, apply it as soon as you remember. If it is close to your next scheduled dose, skip the missed dose and continue with your regular application schedule. Do not double up on doses.
Can I use Vtama alongside other psoriasis treatments?
You should consult your healthcare provider before using Vtama with other topical or systemic treatments, as combining therapies may increase the risk of side effects.
Comprehensive Drug Guide
How Does Vtama Work?
Vtama works by activating the aryl hydrocarbon receptor (AhR) in skin cells, which helps regulate the body’s immune response and reduce inflammation. By targeting AhR, Vtama helps decrease the overproduction of skin cells and the inflammation associated with plaque psoriasis, leading to a reduction in the severity of plaques, redness, and scaling.
Common Dosages
- Topical cream (1%) in tubes for external use.
Typical Dosing
- Apply a thin layer of Vtama once daily to the affected areas of the skin. Wash your hands before and after applying the cream, unless you are treating your hands. Follow your healthcare provider’s instructions regarding the duration of treatment.
Typical Dosing
FDA Approved Indications
- Treatment of plaque psoriasis in adults.
Who Shouldn't Take Vtama?
- Known hypersensitivity or allergy to tapinarof or any other components of the cream.
- Open wounds, severely irritated, or broken skin, unless advised by a healthcare provider.
Advice From The Pharmacist
- Apply Vtama only to clean, dry skin. Avoid applying it to the face, groin, or underarms unless specifically directed by your healthcare provider.
- If you experience irritation, redness, or worsening of symptoms, discontinue use and contact your healthcare provider.
- Do not cover treated areas with bandages, wraps, or tight clothing unless instructed by your healthcare provider.
- Avoid exposure to sunlight or tanning beds while using Vtama, as it may increase skin sensitivity to UV light.
Side Effects of Vtama
Common Side Effects
- Skin redness or irritation at the application site
- Itching
- Pain or burning sensation
Uncommon/Severe Side Effects
- Severe allergic reactions (e.g., rash, swelling, difficulty breathing)
- Persistent or worsening skin irritation
Risks and Warnings of Vtama
- Skin Irritation: Vtama may cause skin irritation, including redness, burning, or itching. If the irritation persists or worsens, contact your healthcare provider.
- Sun Sensitivity: Vtama may increase sensitivity to sunlight. Avoid excessive sun exposure and use sunscreen or protective clothing while using this medication.
Interactions with Vtama
Common Drug Interactions
- Topical corticosteroids: Avoid using other topical treatments, including corticosteroids, on the same area as Vtama unless directed by your healthcare provider, as it may increase the risk of skin irritation.
- Photosensitizing agents: Avoid using medications that increase skin sensitivity to light while using Vtama, as they may enhance the risk of sunburn.
Alternatives to Vtama
- Tazorac (tazarotene): A topical retinoid used to treat plaque psoriasis.
- Dovonex (calcipotriene): A topical vitamin D analog used for the treatment of mild to moderate plaque psoriasis.
- Clobetasol (topical corticosteroid): A potent topical steroid used for treating psoriasis and other inflammatory skin conditions.
- Otezla (apremilast): An oral medication used to treat plaque psoriasis in patients who prefer systemic therapy.
