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TobraDex ST
TobraDex ST is a combination medication containing tobramycin, an aminoglycoside antibiotic, and dexamethasone, a corticosteroid. It is used to treat eye infections and reduce inflammation in conditions such as bacterial conjunctivitis and other ocular infections. Tobramycin helps eliminate bacteria, while dexamethasone reduces inflammation, swelling, and discomfort. The "ST" formulation is designed for better suspension, ensuring consistent dosing with every drop.
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Frequently Asked Questions
How long does it take for TobraDex ST to start working?
TobraDex ST may start relieving symptoms of infection and inflammation within 1 to 2 days of starting treatment. However, full treatment duration is typically 7 to 10 days, depending on the severity of the infection.
Can I use TobraDex ST for viral eye infections?
No, TobraDex ST is specifically used for bacterial eye infections. It should not be used for viral infections like herpes simplex or viral conjunctivitis.
What should I do if I miss a dose of TobraDex ST?
If you miss a dose, apply it as soon as you remember. If it’s close to the time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
Can TobraDex ST cause blurred vision?
Yes, temporary blurred vision is a common side effect after applying the eye drops. This should resolve within a few minutes after administration.
How long should I use TobraDex ST?
TobraDex ST should be used for the full duration prescribed by your healthcare provider, usually for 7 to 10 days. Do not stop using it early, even if your symptoms improve, to ensure the infection is fully treated.
Comprehensive Drug Guide
How Does TobraDex ST Work?
TobraDex ST combines the antibacterial action of tobramycin and the anti-inflammatory effects of dexamethasone. Tobramycin works by inhibiting bacterial protein synthesis, leading to the death of the bacteria. Dexamethasone reduces inflammation by suppressing the body’s immune response to infection, decreasing swelling, redness, and discomfort in the eye.
Common Dosages
- Ophthalmic suspension: 0.3% tobramycin, 0.05% dexamethasone
Typical Dosing
- For eye infections: The usual dosing regimen is one drop every 4 to 6 hours in the affected eye(s). For more severe infections, dosing may be increased to one drop every 2 hours during the first 24 to 48 hours, followed by a reduced frequency as symptoms improve.
Typical Dosing
FDA Approved Indications
- Treatment of external ocular bacterial infections
- Inflammation associated with bacterial infections of the eye
Who Shouldn't Take TobraDex ST?
- Viral, fungal, or mycobacterial eye infections, such as herpes simplex keratitis
- Known hypersensitivity to tobramycin, dexamethasone, or any other components of the formulation
Advice From The Pharmacist
- Shake the bottle well before each use to ensure proper mixing of the suspension.
- Administer the eye drops as prescribed, making sure not to touch the dropper tip to any surface, including your eye, to avoid contamination.
- Do not wear contact lenses while using TobraDex ST, as lenses may further irritate the eye or increase the risk of infection.
- Continue using TobraDex ST for the full prescribed duration, even if symptoms improve, to prevent the infection from returning.
Side Effects of TobraDex ST
Common Side Effects
- Temporary blurred vision after administration
- Eye redness or irritation
- Sensitivity to light (photophobia)
- Eye discomfort or itching
Uncommon/Severe Side Effects
- Increased intraocular pressure (IOP)
- Glaucoma or damage to the optic nerve (with prolonged use)
- Cataract formation (with prolonged use)
- Severe allergic reactions (rash, swelling, difficulty breathing)
Risks and Warnings of TobraDex ST
- Increased Intraocular Pressure: Prolonged use of corticosteroids like dexamethasone may cause increased IOP, leading to glaucoma. Regular monitoring of eye pressure is recommended for patients using TobraDex ST long-term.
- Infection Risk: Steroids can mask or worsen existing infections, especially viral or fungal infections. Discontinue use if signs of non-bacterial infection develop.
- Cataract Formation: Long-term use of corticosteroids may lead to cataract formation. Regular eye exams are advised for patients using TobraDex ST over extended periods.
Interactions with TobraDex ST
Common Drug Interactions
- Other corticosteroids: Using other corticosteroid-containing products alongside TobraDex ST may increase the risk of side effects, such as increased intraocular pressure or cataract formation.
- Nonsteroidal anti-inflammatory drugs (NSAIDs): Caution is advised when using NSAIDs, as they may increase the risk of eye complications like corneal ulcers.
Alternatives to TobraDex ST
- Tobradex: A similar combination of tobramycin and dexamethasone in standard suspension form.
- Maxitrol (neomycin, polymyxin B, dexamethasone): Another combination antibiotic and corticosteroid used for eye infections.
- Prednisolone acetate: A corticosteroid eye drop used for inflammation without the antibiotic component.
- Vigamox (moxifloxacin): A fluoroquinolone antibiotic eye drop used for bacterial infections without the anti-inflammatory component.
