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Timoptic Ocudose
Timoptic Ocudose (generic name: timolol maleate) is a preservative-free ophthalmic solution used to treat elevated intraocular pressure (IOP) in patients with ocular hypertension or open-angle glaucoma. As a beta-blocker, Timoptic Ocudose works by reducing the production of fluid in the eye, which helps lower eye pressure and reduces the risk of optic nerve damage. The preservative-free formulation is ideal for patients sensitive to preservatives in traditional eye drops.
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Frequently Asked Questions
How long does it take for Timoptic Ocudose to lower eye pressure?
Timoptic Ocudose typically begins lowering intraocular pressure within 30 minutes to 1 hour after application, with maximum effects seen after about 2 hours.
Can I use Timoptic Ocudose with contact lenses?
Yes, because Timoptic Ocudose is preservative-free, it can be used with contact lenses. However, you should remove your lenses before applying the drops and wait at least 15 minutes before reinserting them.
What should I do if I miss a dose of Timoptic Ocudose?
If you miss a dose, take it as soon as you remember. If it is close to the time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
Can Timoptic Ocudose cause low blood pressure?
Yes, Timoptic Ocudose can cause systemic effects such as low blood pressure or bradycardia. Pressing on the inner corner of the eye after application can help reduce systemic absorption and minimize these effects.
How is Timoptic Ocudose different from regular Timoptic?
Timoptic Ocudose is preservative-free and comes in single-use vials, making it a good option for patients sensitive to preservatives or who require sterile, preservative-free drops.
Comprehensive Drug Guide
How Does Timoptic Ocudose Work?
Timoptic Ocudose works by blocking beta-adrenergic receptors in the eye, which reduces the production of aqueous humor (the fluid inside the eye). This lowers intraocular pressure, reducing the risk of damage to the optic nerve and preventing vision loss in glaucoma and ocular hypertension patients.
Common Dosages
- 0.25% preservative-free ophthalmic solution
- 0.5% preservative-free ophthalmic solution
Typical Dosing
- For glaucoma and ocular hypertension: The usual dose is one drop of 0.25% or 0.5% solution in the affected eye(s) twice daily. Your healthcare provider may adjust the dosage based on your response.
Typical Dosing
FDA Approved Indications
- Open-angle glaucoma
- Ocular hypertension
Who Shouldn't Take Timoptic Ocudose?
- Bronchial asthma or a history of asthma
- Severe chronic obstructive pulmonary disease (COPD)
- Bradycardia or heart block greater than first degree
- Heart failure
- Known hypersensitivity to timolol or any of its components
Advice From The Pharmacist
- Use one vial per application, and discard any remaining solution after use.
- Administer the drops as directed, typically twice daily. Avoid touching the dropper tip to your eye or any surface to prevent contamination.
- Press on the inner corner of the eye for 1 to 2 minutes after applying the drops to reduce systemic absorption.
- Do not stop using Timoptic Ocudose without consulting your doctor, as sudden discontinuation can lead to a spike in intraocular pressure.
Side Effects of Timoptic Ocudose
Common Side Effects
- Temporary blurred vision
- Mild burning or stinging in the eye
- Dry eyes or excessive tearing
- Headache
Uncommon/Severe Side Effects
- Shortness of breath or wheezing
- Bradycardia (slow heart rate)
- Dizziness or fainting
- Severe allergic reactions (rash, swelling, difficulty breathing)
Risks and Warnings of Timoptic Ocudose
- Respiratory Effects: Timoptic Ocudose may worsen breathing difficulties in patients with asthma or COPD. Avoid use in these patients unless absolutely necessary.
- Cardiac Effects: Timoptic Ocudose can slow the heart rate and lower blood pressure. Monitor for signs of bradycardia and hypotension, especially in patients with pre-existing heart conditions.
- Systemic Absorption: Reducing systemic absorption by pressing on the inner corner of the eye after application can help minimize side effects such as low blood pressure and bradycardia.
Interactions with Timoptic Ocudose
Common Drug Interactions
- Beta-blockers: Using Timoptic Ocudose with systemic beta-blockers (e.g., atenolol, metoprolol) can increase the risk of bradycardia and low blood pressure.
- Calcium channel blockers: Combining Timoptic Ocudose with calcium channel blockers like verapamil or diltiazem can increase the risk of cardiovascular side effects.
- Digoxin: Timoptic Ocudose may enhance the effects of digoxin, increasing the risk of bradycardia.
Alternatives to Timoptic Ocudose
- Latanoprost (Xalatan): A prostaglandin analog used to lower intraocular pressure.
- Brimonidine (Alphagan): An alpha agonist used for glaucoma and ocular hypertension.
- Dorzolamide (Trusopt): A carbonic anhydrase inhibitor for lowering intraocular pressure.
- Travoprost (Travatan Z): A prostaglandin analog used to treat glaucoma and ocular hypertension.
