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Dorzolamide HCl
Dorzolamide is an ophthalmic drug used primarily as an option for the treatment of glaucoma and other ocular hypertension conditions. It works by decreasing the amount of fluid that can build up in the eye, hence reducing pressure.
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Frequently Asked Questions
Can I use Dorzolamide if I use contact lenses?
Dorzolamide contains a preservative that may be absorbed by soft contact lenses. It is advisable to remove contact lenses before administration of the eye drop and wait at least 15 minutes before reinserting.
Why do I taste something strange after using the eye drops?
Dorzolamide may cause a weird taste in your mouth after usage. This is a common side effect and is usually harmless.
Can Dorzolamide permanently cure glaucoma?
Dorzolamide helps manage symptoms of glaucoma but cannot permanently cure the condition. Always follow the dosing regimen given by your physician even if symptoms improve.
I missed a dose of Dorzolamide, what should I do?
Not to worry! If it is close to the time of your next dose, skip the missed dose and go back to your normal time. Do not take 2 doses at the same time or extra doses.
Comprehensive Drug Guide
How Does Dorzolamide HCl Work?
Dorzolamide works as a carbonic anhydrase inhibitor. It diminishes the active secretion of aqueous humor, a fluid in the eye, which subsequently leads to reduced intraocular pressure
What is Dorzolamide HCl Used For?
FDA indications: Dorzolamide treats elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma.
Off-label uses: Some physicians use it off-label in treating certain cases of retinitis pigmentosa and cystoid macular edema.
Common Dosages
Eye drops: 2%
Typical Dosing
FDA Approved Indications
- For FDA-approved indications:
- Glaucoma and other ocular hypertension: 1 drop in the affected eye(s) 3 times a day.
Off-Label Uses
- For off-label uses:
- Retinitis pigmentosa and cystoid macular edema: Dosing should be individualized, based on the physician's assessment.
Who Shouldn't Take Dorzolamide HCl?
- Have known hypersensitivity to Dorzolamide or any other ingredients in the formulation.
- Have severe renal impairment.
- Have hyperchloremic acidosis.
Side Effects of Dorzolamide HCl
Common Side Effects
- - Eye discomfort or irritation
- - Eye redness
- - Blurred vision
- - Bitter or unusual taste in your mouth
Uncommon/Severe Side Effects
- - Rare side effects:
- - Eye pain
- - Sensitivity to light
- - Symptoms of a severe allergic reaction like rash, itching, swelling, severe dizziness, trouble and breathing.
Risks and Warnings of Dorzolamide HCl
- Dorzolamide should be used with caution in individuals with known kidney disease or a history of kidney stones.
- Dorzolamide may cause blurred vision. Avoid driving or hazardous activities until you know how it affects you.
- This drug may potentially cause eye or eyelid irritation. Discuss any allergies with your healthcare provider.
- Contact your healthcare provider immediately if you show signs of an allergic reaction after using Dorzolamide.
Interactions with Dorzolamide HCl
Common Drug Interactions
- High-dose salicylate therapy
Alternatives to Dorzolamide HCl
- Timolol
- Brinzolamide
- Acetazolamide
- Apraclonidine
- Betaxolol
