You're not logged in. Please log in to earn stock or Bitcoin rewards on your prescription purchase.
Apraclonidine HCl
Apraclonidine HCl is the generic form of Iopidine, a medication primarily used to lower intraocular pressure in patients with glaucoma or ocular hypertension. It is also employed to manage increased eye pressure following certain eye surgeries. Apraclonidine HCl belongs to the drug class known as alpha-2 adrenergic agonists, which reduce the production of aqueous humor (the fluid in the eye) to help prevent optic nerve damage and vision loss.
Drug Availability and Controlled Substance Status
Apraclonidine HCl is available as an ophthalmic solution, typically in concentrations of 0.5% for long-term use in glaucoma or ocular hypertension, and 1% for short-term use, particularly after eye surgeries. This medication is not a controlled substance, but it is prescription-only and should be used under the guidance of an ophthalmologist.
Rx. Enter your prescription
How would you like to get your prescription? Select an option
Pharmacy pickup
Select from 35,000 pharmacies
Free two-day delivery
Coming soon!
Find a pharmacy near you. Enter your ZIP code
Are you a member? Sign up or log in.
Members have saved
$NaN
using our savings card for instant savings.
Don't pay full retail price and miss out on potential savings. Try it now—you have nothing to lose!
NaNM
worth of Satoshi has been rewarded to our members.
Everyone who signs up enjoys the benefits of earning FREE Bitcoin with every purchase.
How much Bitcoin can you earn with Apraclonidine HCl ?
The potential for Bitcoin rewards to increase and appreciate in value is a possibility to consider, which may occur over time.
See the value of your savings today
Today's Value
1 Bitcoin = $NaN
Bitcoin (BTC)
...
USD
$NaN
Adjust Bitcoin's potential value to see how much it could be worth
Potential Value
1 Bitcoin =
Bitcoin (BTC)
...
USD
$NaN
Frequently Asked Questions
How quickly does Apraclonidine HCl work?
Apraclonidine HCl typically begins to reduce intraocular pressure within one hour of administration, making it effective for short-term use, especially following eye surgery.
Can Apraclonidine HCl be used with other eye drops?
Yes, Apraclonidine HCl is often used alongside other eye drops to achieve better control of intraocular pressure. Patients should follow their healthcare provider’s instructions on how to use multiple eye drops.
What should I do if I miss a dose?
If you miss a dose of Apraclonidine HCl, use it as soon as you remember, unless it is close to the time for your next dose. Do not double the dose to make up for the missed one.
Is it safe to use Apraclonidine HCl during pregnancy?
The safety of Apraclonidine HCl during pregnancy has not been fully established. Pregnant patients should discuss the risks and benefits with their healthcare provider.
How long can Apraclonidine HCl be used for?
Apraclonidine HCl is generally used for short-term management due to the risk of decreased effectiveness over time. The duration of treatment should be determined by an eye care provider based on the patient’s response and needs.
Comprehensive Drug Guide
How Does Apraclonidine HCl Work?
Apraclonidine HCl works by stimulating alpha-2 adrenergic receptors in the eye, leading to a decrease in the production of aqueous humor, the fluid inside the eye. This reduction in fluid production results in lower intraocular pressure, which is essential in managing glaucoma and preventing further damage to the optic nerve.
Common Dosages
Apraclonidine HCl is commonly available as a 0.5% ophthalmic solution for glaucoma management and a 1% ophthalmic solution for use around the time of eye surgery. The specific dosage and frequency of administration depend on the condition being treated and the patient's response to the medication.
Typical Dosing
For preventing postoperative intraocular pressure increases, the 1% solution is typically administered as one to two drops in the affected eye one hour before and immediately after laser surgery. For long-term glaucoma management, the 0.5% solution is usually instilled in the affected eye(s) two to three times daily. Patients should follow their ophthalmologist's instructions closely to ensure effective pressure control.
Typical Dosing
FDA Approved Indications
Apraclonidine HCl is FDA-approved for the short-term adjunctive treatment of glaucoma and ocular hypertension when additional reduction in intraocular pressure is necessary. It is also indicated for the prevention and treatment of increased intraocular pressure following laser eye surgery, such as laser trabeculoplasty, iridotomy, or capsulotomy.
Who Shouldn't Take Apraclonidine HCl?
Apraclonidine HCl should not be used in patients with a known allergy to apraclonidine, clonidine, or any of the other components of the medication. It is also contraindicated in patients taking monoamine oxidase inhibitors (MAOIs) due to the risk of severe hypertensive reactions. Caution is advised for patients with severe cardiovascular disease or depression.
Advice From The Pharmacist
Patients using Apraclonidine HCl should be careful to avoid contamination of the dropper tip and should not let it touch the eye or any other surface. After applying the drops, it is recommended to gently press the corner of the eye near the nose for about one minute to prevent the medication from draining into the tear duct, which can help improve its effectiveness. If using multiple eye medications, wait at least five minutes between different drops.
Side Effects of Apraclonidine HCl
Common Side Effects
Common side effects of Apraclonidine HCl include eye discomfort, itching, redness, and dry mouth. Some patients may experience systemic effects such as dizziness, fatigue, or drowsiness. In rare cases, serious allergic reactions can occur, leading to symptoms like swelling of the face, tongue, or throat, difficulty breathing, or severe itching. Immediate medical attention is necessary if any of these symptoms develop.
Risks and Warnings of Apraclonidine HCl
The long-term use of Apraclonidine HCl can lead to decreased effectiveness over time (tachyphylaxis) and potential allergic reactions. Patients should be monitored regularly to assess the continued effectiveness of the treatment. Additionally, Apraclonidine HCl can cause drowsiness, so caution is advised when driving or operating machinery until the patient knows how the medication affects them.
Interactions with Apraclonidine HCl
Common Drug Interactions
Apraclonidine HCl may interact with other medications that affect blood pressure, such as beta-blockers or antihypertensives, potentially leading to increased side effects. It should not be used in combination with monoamine oxidase inhibitors (MAOIs) due to the risk of hypertensive crisis. Patients should inform their healthcare provider of all medications and supplements they are taking to avoid harmful interactions.
Alternatives to Apraclonidine HCl
Alternative treatments for lowering intraocular pressure include other classes of glaucoma medications, such as prostaglandin analogs (e.g., latanoprost), beta-blockers (e.g., timolol), and carbonic anhydrase inhibitors (e.g., dorzolamide). The choice of alternative therapy will depend on the patient’s individual condition, response to treatment, and tolerance of side effects.
