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Trusopt
Trusopt (generic name: dorzolamide hydrochloride) is an ophthalmic medication used to treat elevated intraocular pressure (IOP) in individuals with open-angle glaucoma or ocular hypertension. By reducing the amount of fluid produced in the eye, Trusopt helps to lower intraocular pressure, preventing damage to the optic nerve and reducing the risk of vision loss associated with glaucoma.
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Frequently Asked Questions
How long does it take for Trusopt to start lowering eye pressure?
Trusopt usually begins to lower intraocular pressure within a few hours after application, but it may take several days of consistent use to achieve maximum effect.
Can I use Trusopt with other glaucoma medications?
Yes, Trusopt is often used in combination with other glaucoma medications to further lower intraocular pressure. Always follow your healthcare provider's instructions regarding the timing and use of multiple eye drops.
What should I do if I miss a dose of Trusopt?
If you miss a dose, apply it as soon as you remember. If it is close to the time of your next dose, skip the missed dose and continue with your regular schedule. Do not double up on doses.
Can Trusopt cause systemic side effects?
Although Trusopt is applied topically, some systemic absorption can occur, which may lead to side effects like headache, nausea, or fatigue. If you experience any concerning symptoms, inform your healthcare provider.
Is Trusopt safe for long-term use?
Yes, Trusopt is safe for long-term use in managing glaucoma and ocular hypertension, but regular follow-up with your healthcare provider is essential to monitor your eye pressure and overall eye health.
Comprehensive Drug Guide
How Does Trusopt Work?
Trusopt works by inhibiting the enzyme carbonic anhydrase in the ciliary processes of the eye, which reduces the production of aqueous humor (the fluid in the eye). This decrease in fluid production helps to lower intraocular pressure (IOP), thereby reducing the risk of damage to the optic nerve and the progression of glaucoma.
Common Dosages
- 2% ophthalmic solution.
- The usual dosing is one drop in the affected eye(s) two or three times daily.
Typical Dosing
- Apply one drop of Trusopt into the affected eye(s) two to three times daily, as directed by your healthcare provider.
- If using other eye medications, wait at least 10 minutes between applying different eye drops to prevent dilution or washing out of the medications.
Typical Dosing
FDA Approved Indications
- Treatment of elevated intraocular pressure in patients with open-angle glaucoma.
- Management of ocular hypertension.
Who Shouldn't Take Trusopt?
- Hypersensitivity to dorzolamide or any other component of the formulation.
- Severe kidney impairment, as dorzolamide is a sulfonamide derivative and may cause side effects in individuals with kidney dysfunction.
Advice From The Pharmacist
- Wash your hands before using Trusopt to avoid contamination.
- Tilt your head back and gently pull down your lower eyelid to create a small pocket, then place the drop in the eye. Close your eyes for a minute or two, pressing lightly on the inside corner of your eye to prevent the medication from draining.
- To avoid contamination of the solution, do not let the tip of the dropper touch your eye or any other surface.
- Store the medication at room temperature and keep the bottle tightly closed when not in use.
Side Effects of Trusopt
Common Side Effects
- Burning or stinging sensation in the eye after application
- Blurred vision
- Bitter taste in the mouth
- Eye discomfort or dryness
Uncommon/Severe Side Effects
- Severe allergic reactions (rash, itching, swelling, difficulty breathing)
- Eye inflammation or swelling
- Corneal edema (swelling of the cornea)
Risks and Warnings of Trusopt
- Sulfa Allergy: Trusopt is a sulfonamide derivative, and individuals with a known allergy to sulfa drugs should use this medication cautiously or avoid it altogether.
- Kidney Disease: Patients with severe kidney impairment may experience side effects from Trusopt. Your healthcare provider will assess your kidney function before prescribing this medication.
- Potential Systemic Absorption: Although applied topically, some of the medication may be absorbed systemically, potentially causing side effects such as fatigue, headache, or taste disturbances.
Interactions with Trusopt
Common Drug Interactions
- Oral carbonic anhydrase inhibitors (e.g., acetazolamide): Using both oral and topical carbonic anhydrase inhibitors may increase the risk of systemic side effects, such as electrolyte imbalances.
- Other eye medications: If you are using other eye drops or medications, wait at least 10 minutes between applying Trusopt and the other products.
Alternatives to Trusopt
- Timolol: A beta-blocker eye drop used to reduce intraocular pressure in patients with glaucoma or ocular hypertension.
- Brimonidine: An alpha agonist used to lower intraocular pressure in individuals with open-angle glaucoma or ocular hypertension.
- Latanoprost: A prostaglandin analog used to increase the outflow of fluid from the eye, reducing intraocular pressure.
- Combigan: A combination of brimonidine and timolol, used to treat elevated intraocular pressure.
