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Solifenacin Succinate
Solifenacin is a type of medication known as an antimuscarinic agent or bladder relaxant. It's used for treating symptoms of an overactive bladder, like frequent or urgent urination, and incontinence. Some common side effects include dry mouth, blurred vision, and constipation, but these usually diminish with continued use.
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Frequently Asked Questions
Can I take Solifenacin if I have glaucoma?
Usually not, but it depends on the type of glaucoma. Be sure to discuss this important detail with your healthcare provider.
Does Solifenacin make you constipated?
Yes, it's a common side effect. Eating a high-fiber diet, drinking plenty of fluids, and staying active can help manage this side effect.
I missed a dose of Solifenacin, what should I do?
Not to worry. If it's close to the time for your next dose, just skip the missed one. Otherwise, take it as soon as you remember. But never take two doses at the same time!
Can I just stop taking Solifenacin after my symptoms are gone?
No, it's crucial to continue taking Solifenacin exactly as prescribed by your healthcare provider, even if your symptoms improve. Stopping abruptly could cause your symptoms to return.
Will Solifenacin affect my vision?
It could. Blurred vision is one of the common side effects. If you notice significant changes in your vision, reach out to your healthcare provider immediately.
Comprehensive Drug Guide
How Does Solifenacin Succinate Work?
Solifenacin is a competitive cholinergic receptor antagonist, selective for the M3 receptor subtype, which is primarily responsible for bladder muscle contractions. By blocking these receptors, Solifenacin reduces bladder spasms, thereby controlling symptoms of an overactive bladder.
What is Solifenacin Succinate Used For?
FDA indications: Solifenacin is used to treat overactive bladder (OAB) with symptoms of urge urinary incontinence, urgency, and urinary frequency.
Off-label uses: Sometimes doctors may use Solifenacin off-label for managing neurogenic bladder and nocturia.
Common Dosages
Tablets: 5mg, 10mg
Typical Dosing
FDA Approved Indications
- For FDA-approved indications:
- Overactive bladder: Start with 5mg once daily, if needed the dose can be increased to 10mg once daily.
Off-Label Uses
- For off-label uses:
- Neurogenic bladder and nocturia: Dosages are individualized by healthcare providers.
Who Shouldn't Take Solifenacin Succinate?
- Have urinary or gastric retention.
- Have uncontrolled narrow-angle glaucoma.
- Have hypersensitivity to solifenacin.
- Have severe liver or kidney disease
Advice From The Pharmacist
- Solifenacin may cause blurred vision, drowsiness, or dizziness. Avoid tasks like driving until you know how it affects you.
- Stay well-hydrated to avoid constipation.
- This medication may cause a dry mouth. Sugar-free candies or gum may help, and make sure to brush your teeth regularly as dry mouth can lead to tooth decay.
- Take Solifenacin exactly as directed by your doctor. Do not take more or less of it, and do not take it more often than prescribed.
- Immediately report difficulty urinating, vision changes, or severe abdominal pain to your doctor.
Side Effects of Solifenacin Succinate
Common Side Effects
- Dry mouth
- Blurred vision
- Constipation
- Nausea
- Dizziness
Uncommon/Severe Side Effects
- Rare side effects:
- Reduced sweating
- Increased body temperature
- Hallucinations
- Severe side effects:
- Painful urination
- Severe constipation
- Severe dizziness/fainting
Risks and Warnings of Solifenacin Succinate
- Remember, Solifenacin can lead to problematic side effects in certain cases.
- If you have a history of narrow-angle glaucoma, gastric retention, or severe liver and kidney diseases, avoid Solifenacin unless specifically indicated by your healthcare provider.
- If you're pregnant, trying to become pregnant, or breastfeeding, always consult your healthcare provider.
- If you experience difficulty urinating, severe abdominal pain, or sudden vision changes, seek medical help immediately.
Interactions with Solifenacin Succinate
Common Drug Interactions
- Amantadine
- Cimetidine
- Ketoconazole
- Thiazide diuretics (such as hydrochlorothiazide)
Alternatives to Solifenacin Succinate
- Oxybutynin
- Tolterodine
- Darifenacin
- Trospium
- Fesoterodine
