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Imitrex STATdose Refill

Imitrex STATdose Refill (sumatriptan) is a triptan medication specifically designed for the acute treatment of migraine attacks. This refill is intended for use with the Imitrex STATdose System, which provides rapid relief of migraine symptoms through a convenient subcutaneous injection method. The STATdose System allows patients to self-administer the medication at the onset of a migraine, helping to alleviate symptoms such as headache, nausea, and sensitivity to light and sound.



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Frequently Asked Questions

How long does it take for Imitrex STATdose Refill to start working?
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Patients may begin to feel relief within 10 to 20 minutes after injection, with peak effects occurring within 1 to 2 hours.

Can I take Imitrex STATdose Refill with other medications?
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Always consult your healthcare provider before combining Imitrex with other medications, especially other migraine treatments.

What should I do if I miss a dose of Imitrex STATdose Refill?
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If a dose is missed, it should be used as soon as you remember. If it’s close to the time for your next scheduled dose, skip the missed dose and continue with your regular schedule.

What should I do if I miss a dose of Imitrex STATdose Refill?
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If a dose is missed, it should be used as soon as you remember. If it’s close to the time for your next scheduled dose, skip the missed dose and continue with your regular schedule.

Is it safe to use Imitrex STATdose Refill during pregnancy?
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Imitrex should be used during pregnancy only if clearly needed, and the risks and benefits should be discussed with a healthcare provider.

Can Imitrex STATdose Refill cause weight gain?
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Weight gain is not a common side effect of Imitrex; however, any significant changes in health should be discussed with a healthcare provider.

Can Imitrex STATdose Refill cause weight gain?
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Weight gain is not a common side effect of Imitrex; however, any significant changes in health should be discussed with a healthcare provider.

Comprehensive Drug Guide

How Does Imitrex STATdose Refill Work?

Sumatriptan works by agonizing serotonin (5-HT) receptors in the brain, particularly the 5-HT1B and 5-HT1D subtypes. This action leads to vasoconstriction of cranial blood vessels and inhibits the release of pro-inflammatory neuropeptides, effectively alleviating migraine symptoms.



What is Imitrex STATdose Refill Used For?

  • Acute treatment of migraine attacks with or without aura.


Common Dosages

  • Injection: Commonly available as a 6 mg dose in a pre-filled syringe or autoinjector.

Typical Dosing

  • The recommended dose for adults is 6 mg administered subcutaneously at the onset of a migraine attack. If symptoms do not improve after 1 hour, a second dose may be administered, but the total daily dose should not exceed 12 mg.


Typical Dosing

FDA Approved Indications

  • Known hypersensitivity to sumatriptan or any components of the formulation
  • History of ischemic heart disease, coronary artery disease, or uncontrolled hypertension
  • Severe hepatic impairment


Who Shouldn't Take Imitrex STATdose Refill?

  • Patients should be educated on the proper technique for self-administering the injection to ensure effective delivery of the medication.
  • Advise patients to seek medical attention if they experience chest pain, tightness, or other concerning symptoms after administration.
  • Remind patients that Imitrex is intended for the treatment of acute migraine attacks and not for preventive therapy.


Advice From The Pharmacist

  • Patients should be educated on the proper technique for self-administering the injection to ensure effective delivery of the medication.
  • Advise patients to seek medical attention if they experience chest pain, tightness, or other concerning symptoms after administration.
  • Remind patients that Imitrex is intended for the treatment of acute migraine attacks and not for preventive therapy.


Side Effects of Imitrex STATdose Refill

Common Side Effects

  • Injection site reactions (redness, swelling, pain)
  • Dizziness
  • Drowsiness
  • Nausea
  • Sensations of tingling or warmth


Uncommon/Severe Side Effects

  • Chest pain or tightness
  • Severe allergic reactions (anaphylaxis)
  • Serotonin syndrome (especially if combined with other serotonergic agents)


Risks and Warnings of Imitrex STATdose Refill

  • Cardiovascular Risk: Monitor for signs of cardiovascular events, especially in patients with a history of heart disease.
  • Medication Overuse Headache: Frequent use of Imitrex can lead to rebound headaches; limit usage according to healthcare provider recommendations.


Interactions with Imitrex STATdose Refill

Common Drug Interactions

  • Other Triptans: Use caution when using Imitrex with other triptan medications to avoid increased risk of adverse effects.
  • Monoamine Oxidase Inhibitors (MAOIs): Concomitant use may increase the risk of sumatriptan toxicity.


Alternatives to Imitrex STATdose Refill

  • Other Triptans: Such as rizatriptan or zolmitriptan for acute migraine treatment.
  • Ergotamine derivatives: For migraine management.
  • Non-steroidal anti-inflammatory drugs (NSAIDs): Such as ibuprofen for mild to moderate migraine relief.