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Fenofibric Acid
Fenofibric Acid, also known as Trilipix, is often used to lower cholesterol and triglyceride levels in the blood. It ??s generally prescribed alongside a proper diet to reduce the chances of atherosclerosis (clogged arteries) and prevent pancreatitis. Common side effects include back pain, headache, and a runny or stuffy nose.
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Frequently Asked Questions
Can I drink alcohol while taking Fenofibric acid?
Alcohol may increase the risk of liver problems. It is best to avoid alcohol when taking this drug.
I ??ve read that Fenofibric acid is related to gemfibrozil, which I ??m allergic to. Should I avoid fenofibric acid?
Yes, if you ??re allergic to gemfibrozil, you shouldn ??t take fenofibric acid or any medications that contain fenofibrate since they ??re from the same family of medications and you could experience a similar allergic reaction.?
Should I take Fenofibric acid with food?
Fenofibric Acid can be taken with or without food. It's most important to take it consistently, at the same time each day.
What should I do if I forget a dose?
If you forget a dose, take it as soon as you remember. If it ??s nearly time for your next dose, skip the missed dose. Do not take two doses at once to make up for the missed dose.?
Comprehensive Drug Guide
How Does Fenofibric Acid Work?
Fenofibric acid reduces triglycerides by boosting the oxidation of fatty acids in liver mitochondria while upregulating plasma lipoprotein lipase production. Its net effect is an improved lipid profile.
What is Fenofibric Acid Used For?
FDA Indications: Fenofibric Acid is used to lower 'bad' cholesterol and triglycerides and to raise 'good' cholesterol in combination with a lowfat diet and other nondietary interventions.
Offlabel uses: Doctors sometimes prescribe it to patients with high levels of triglycerides in the blood, hyperlipidemia, or combined hyperlipidemia.
Common Dosages
Capsules: 45mg and 135mg
Typical Dosing
FDA Approved Indications
- For FDAapproved indications: The usual dose is 135mg to be taken once a day.
Who Shouldn't Take Fenofibric Acid?
- Pregnant women or those planning to become pregnant, as the drug could potentially harm the baby.
- People with liver disease.
- Patients with severe kidney disease.
- People allergic to any ingredient of fenofibric acid or similar drugs.
- Patients who have had a previous hypersensitivity reaction to fenofibrate or fenofibric acid.
Advice From The Pharmacist
- Take this medication exactly as prescribed, even if you feel well.
- Fenofibric Acid should be swallowed whole, with a full glass of water.
- You can take this medication without regard to meals.
- It's important to continue to follow your doctor ??s advice about diet and exercise.
- Don't take more than the recommended dose.
- Avoid drinking alcohol while taking this drug.
Side Effects of Fenofibric Acid
Common Side Effects
- You might feel an upset stomach, and experience indigestion, or diarrhea.
- Back pain and headaches can occasionally occur.
- You might experience mild rashes or hives on the skin.
Uncommon/Severe Side Effects
- Uncommon side effects:
- You might get muscle pain or weakness, sometimes accompanied by fever.
- Rarely you could encounter jaundice a yellowing of the skin or eyes.
- Rare side effects:
- Development or worsening of gallstones is a rare but reported side effect.
- Liver problems can occur, usually indicated by severe nausea, vomiting, abdominal pain, or dark urine.
- Severe side effects:
- If you have signs of serious muscle problems such as persistent muscle pain or weakness accompanied by fever or unusual fatigue, seek medical assistance immediately.
- Cases of severe skin issues like StevensJohnson syndrome or toxic epidermal necrolysis, indicative of severe rash, swelling, blisters, or changes in skin color, require immediate medical attention.
- In case you observe warning signs of a serious allergic reaction, such as rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, or trouble breathing; seek emergency medical attention.
Risks and Warnings of Fenofibric Acid
- People with liver disease or severe kidney disease should avoid this drug.
- It ??s essential to understand that cholesterol is also formed through the diet, so taking this drug should be combined with a lowcholesterol diet.
- Fenofibric Acid can occasionally cause muscle problems which can lead to serious conditions such as rhabdomyolysis. If you notice muscle pain, weakness, or tenderness, call your healthcare provider.
Interactions with Fenofibric Acid
Common Drug Interactions
- Colchicine
- Coumarin anticoagulants
- HMGCoA reductase inhibitors
Alternatives to Fenofibric Acid
- Atorvastatin
- Rosuvastatin
- Pravastatin
- Simvastatin
- Lovastatin
