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Dritho-Creme HP

Dritho-Creme HP contains the active ingredient anthralin, which is used to treat psoriasis, a chronic skin condition characterized by red, scaly patches. It belongs to the antipsoriatic drug class and works by slowing down the growth of skin cells, which helps to reduce inflammation and plaque formation. Dritho-Creme HP is typically used for short-term treatment to manage flare-ups of psoriasis, especially on the scalp and other areas with thickened plaques.



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Frequently Asked Questions

How quickly does Dritho-Creme HP work?
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You may start to see improvements in your psoriasis symptoms within 2-4 weeks of regular use. However, complete clearance may take longer, depending on the severity of the condition.

Can I leave Dritho-Creme HP on my skin overnight?
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No, Dritho-Creme HP is typically used as a short-contact therapy, meaning it should be left on the skin for 10-30 minutes before rinsing off. Leaving it on for longer periods may increase the risk of skin irritation.

Does Dritho-Creme HP permanently stain the skin?
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The cream may cause temporary skin discoloration, especially if used for prolonged periods. The staining usually fades after stopping treatment.

Can I use Dritho-Creme HP on my face?
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Dritho-Creme HP is not recommended for use on the face due to the risk of irritation. It is typically used on thicker skin areas, such as the scalp, elbows, or knees.

What should I do if I experience severe skin irritation?
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If you experience severe irritation, stop using the cream and contact your healthcare provider. They may recommend adjusting the application time or discontinuing use altogether.

Comprehensive Drug Guide

How Does Dritho-Creme HP Work?

Anthralin, the active ingredient in Dritho-Creme HP, works by reducing the excessive growth of skin cells that characterizes psoriasis. It slows down cell production in the outer layer of the skin and reduces inflammation. As a result, scaling, redness, and plaque formation are minimized, allowing the skin to heal over time.



Common Dosages

Dritho-Creme HP is typically available in a 0.5% concentration of anthralin cream.

Typical Dosing

  • The usual dosing is to apply a thin layer of the cream to the affected areas once daily, generally for 10-30 minutes (referred to as short-contact therapy), then rinse off thoroughly to minimize irritation.
  • Your healthcare provider may adjust the application time based on your skin’s reaction to the treatment.


Typical Dosing

FDA Approved Indications

Chronic plaque psoriasis, particularly on areas with thicker skin, such as the scalp, elbows, and knees.

Who Shouldn't Take Dritho-Creme HP?

  • Patients with acute psoriasis or psoriatic erythroderma, as these conditions may worsen with anthralin.
  • Known allergy or hypersensitivity to anthralin or any other component of the cream.
  • Areas of inflamed, irritated, or broken skin should not be treated with Dritho-Creme HP.

Advice From The Pharmacist

  • Apply Dritho-Creme HP to clean, dry skin, being careful to avoid contact with unaffected areas or mucous membranes, such as the eyes.
  • After application, wash your hands thoroughly to avoid spreading the cream to sensitive areas.
  • The cream may stain clothing, towels, or skin, so be cautious when applying it. Use old clothing or towels if necessary.
  • Store Dritho-Creme HP in a cool, dry place and keep it out of reach of children.


Side Effects of Dritho-Creme HP

Common Side Effects

  • Temporary skin irritation or redness at the site of application
  • Skin staining or discoloration (especially with long-term use)
  • Itching or burning sensations


Uncommon/Severe Side Effects

  • Severe skin irritation or allergic reactions
  • Photosensitivity (increased sensitivity to sunlight)

Risks and Warnings of Dritho-Creme HP

  • Skin Irritation: Dritho-Creme HP may cause irritation, especially if left on for too long or applied too frequently. Follow the dosing instructions carefully and rinse off the cream as directed.
  • Staining: Anthralin can stain the skin and clothing. Avoid contact with fabrics and wash the cream off after the prescribed application time to minimize staining.
  • Photosensitivity: Prolonged exposure to sunlight should be avoided while using Dritho-Creme HP, as it can increase the risk of sunburn or skin damage.

Interactions with Dritho-Creme HP

Common Drug Interactions

There are no significant drug interactions reported with Dritho-Creme HP, as it is a topical treatment. However, inform your healthcare provider if you are using other topical medications for psoriasis or other skin conditions.

Alternatives to Dritho-Creme HP

  • Topical corticosteroids: Often used to reduce inflammation and itching associated with psoriasis.
  • Calcipotriene (Dovonex): A vitamin D analog used to treat plaque psoriasis.
  • Tazarotene (Tazorac): A topical retinoid that helps reduce plaque buildup in psoriasis.
  • Coal tar: Another topical treatment that helps slow skin cell growth in psoriasis.
  • Phototherapy: A treatment option using ultraviolet light for moderate to severe psoriasis.