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Dexmethylphenidate HCl ER
Dexmethylphenidate HCl ER is an extended-release central nervous system (CNS) stimulant used to treat attention-deficit hyperactivity disorder (ADHD) in both children and adults. It helps increase focus, attention, and impulse control by altering the levels of dopamine and norepinephrine in the brain. The extended-release (ER) formulation provides a sustained release of the medication over the day, requiring only once-daily dosing.
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Frequently Asked Questions
How long does it take for Dexmethylphenidate HCl ER to start working?
Effects usually begin within 30 to 60 minutes after taking the medication, with the extended-release formulation lasting up to 12 hours.
What should I do if I miss a dose?
Take the missed dose as soon as you remember, unless it is close to the time of the next dose. Do not take an extra dose to make up for the missed one.
Can I drink caffeine while taking Dexmethylphenidate HCl ER?
It's best to limit caffeine intake while on this medication, as both caffeine and dexmethylphenidate are stimulants, and combining them can increase side effects like nervousness and increased heart rate.
Is Dexmethylphenidate HCl ER safe for long-term use?
Yes, when taken as prescribed and monitored by a healthcare provider, Dexmethylphenidate HCl ER is generally safe for long-term use. Regular check-ups will ensure its continued safety and effectiveness.
Can Dexmethylphenidate HCl ER affect my sleep?
Yes, this medication can cause insomnia, especially if taken later in the day. To minimize sleep disturbances, take it in the morning as directed.
Comprehensive Drug Guide
How Does Dexmethylphenidate HCl ER Work?
Dexmethylphenidate HCl ER works by blocking the reuptake of dopamine and norepinephrine in the brain, which increases their levels. This action improves attention and focus and decreases hyperactivity and impulsivity, making it effective for treating ADHD.
What is Dexmethylphenidate HCl ER Used For?
Treatment of ADHD in children aged 6 years and older, as well as in adults
Common Dosages
Dexmethylphenidate HCl ER is available in the following strengths:
- 5 mg extended-release capsules
- 10 mg extended-release capsules
- 15 mg extended-release capsules
- 20 mg extended-release capsules
- 25 mg extended-release capsules
- 30 mg extended-release capsules
- 35 mg extended-release capsules
- 40 mg extended-release capsules
Typical Dosing
FDA Approved Indications
The typical starting dose for children and adults is 10 mg once daily in the morning, with adjustments made based on response and tolerance. The dose may be increased in 5 mg to 10 mg increments at weekly intervals.
Who Shouldn't Take Dexmethylphenidate HCl ER?
Dexmethylphenidate HCl ER should not be used in individuals with:
- Known hypersensitivity to methylphenidate or dexmethylphenidate
- Severe anxiety, tension, or agitation
- Glaucoma
- Tics or Tourette syndrome
- Concurrent use of monoamine oxidase inhibitors (MAOIs) or within 14 days of stopping MAOI treatment
Advice From The Pharmacist
- Take Dexmethylphenidate HCl ER once daily in the morning to avoid interference with sleep. Avoid taking it late in the day.
- Swallow the extended-release capsules whole. If you have difficulty swallowing, the capsule can be opened and sprinkled on a small amount of applesauce, but consumed immediately without chewing.
- This medication may decrease appetite, so monitor your food intake and weight, especially in children. Ensure a balanced diet is maintained.
- Regularly monitor blood pressure and heart rate while on this medication, as it can increase both.
Side Effects of Dexmethylphenidate HCl ER
Common Side Effects
- Decreased appetite
- Insomnia
- Dry mouth
- Headache
- Stomach pain
- Nervousness or irritability
Uncommon/Severe Side Effects
- Increased blood pressure or heart rate
- Psychiatric symptoms, such as new or worsening aggression or hostility
- Heart-related issues, such as chest pain or shortness of breath
- Growth suppression in children (with long-term use)
Risks and Warnings of Dexmethylphenidate HCl ER
- Abuse and Dependence: Dexmethylphenidate HCl ER has a high potential for abuse, especially in individuals with a history of substance abuse. Use this medication exactly as prescribed, and do not share it with others.
- Cardiovascular Risks: Stimulants can increase heart rate and blood pressure. Patients with pre-existing heart conditions should be monitored closely, and the medication should be used with caution.
- Growth Suppression: In children, long-term use of this medication may lead to slowed growth. Regular monitoring of height and weight is recommended during treatment.
Interactions with Dexmethylphenidate HCl ER
Common Drug Interactions
- Monoamine oxidase inhibitors (MAOIs): Taking dexmethylphenidate with MAOIs can cause serious reactions, including a hypertensive crisis.
- Antihypertensives: This medication may reduce the effectiveness of medications used to lower blood pressure.
- Acid reducers or antacids: These may affect the absorption of dexmethylphenidate and alter its effectiveness.
Alternatives to Dexmethylphenidate HCl ER
- Methylphenidate (Ritalin LA, Concerta): Another stimulant used to treat ADHD with similar mechanisms of action.
- Lisdexamfetamine (Vyvanse): A stimulant medication used to treat ADHD and binge eating disorder, with less potential for abuse.
- Atomoxetine (Strattera): A non-stimulant alternative for treating ADHD by selectively inhibiting norepinephrine reuptake.
- Guanfacine ER (Intuniv): A non-stimulant ADHD treatment, especially used for children and adolescents.
