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Desloratadine
Desloratadine is an antihistamine medication that is commonly used to relieve allergy symptoms. This may include watery eyes, runny nose, itching or burning eyes, and sneezing. It also helps to reduce skin hives and itching in people with chronic skin reactions. Common side effects include fatigue, dry mouth, and headache, but your doctor will usually discuss these potential drawbacks before prescribing desloratadine.
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Frequently Asked Questions
Can I drink alcohol while taking desloratadine?
It's not advisable as alcohol can increase the sedative effects of desloratadine.
Can I take desloratadine every day?
Yes, desloratadine is designed to be taken once every day.
Is it safe to take desloratadine during pregnancy or while breastfeeding?
You should talk to your doctor before you take desloratadine if you are pregnant, planning to become pregnant, or breastfeeding.
What should I do if I miss a dose of desloratadine?
If you forget to take a dose, take it as soon as you remember. If you don't remember until the following day, skip the missed dose.
What should I do if I overdose on desloratadine?
Call your local poison control center immediately or go to the nearest emergency room.
Comprehensive Drug Guide
How Does Desloratadine Work?
Desloratadine is a tricyclic H1antihistamine that is an active metabolite of loratadine. It inhibits histamine release, thereby reducing the symptoms associated with allergies.
What is Desloratadine Used For?
FDA indications: Desloratadine is used to treat symptoms of allergies such as itchy/watery/red eyes, rhinorrhea, and sneezing. It is also used to treat itch and hives caused by chronic idiopathic urticaria (CIU).
Offlabel uses: It has been reported that it may alleviate symptoms in some patients with cold urticaria and delayed pressure urticaria.
Common Dosages
Tablets: 5mg
Oral solution: 0.5mg/1mL
Orally disintegrating tablets: 2.5mg, 5mg
Typical Dosing
FDA Approved Indications
- Allergies and chronic idiopathic urticaria: 5mg once a day
Off-Label Uses
- Cold urticaria and delayed pressure urticaria: Desloratadine dosage can range between 5 to 20mg per day based on the severity of symptoms and the individual?s response to the medication.
Who Shouldn't Take Desloratadine?
- People who have had an allergic reaction to loratadine or desloratadine.
- People who have severe liver disease.
- People who have certain types of heart conditions such as long QT syndrome.
- Pregnant women, unless the potential benefits to the mother outweigh the potential risks to the fetus.
- People who are breastfeeding, unless the benefits justify the possible risks to the infant.
Advice From The Pharmacist
- Don't take it with alcohol as it could make side effects worse.
- Avoid driving or operating machinery until you know how desloratadine affects you.
- Tell the doctor if you're on any other medications or have any other health conditions.
- Don?t take more than the recommended dose without consulting your doctor. Overdose can lead to increased heart rate, sleepiness, and headache.
- If you miss a dose, take it as soon as you remember but never double up on doses.
Side Effects of Desloratadine
Common Side Effects
- Fatigue
- Dry mouth
- Headache
Uncommon/Severe Side Effects
- Uncommon side effects:
- Sore throat
- Nausea
- Dizziness
- Rare side effects:
- Fast or irregular heartbeat
- Rash
- Difficulty breathing
- Severe dizziness.
- If you notice other effects not listed above, contact your doctor or pharmacist.
Risks and Warnings of Desloratadine
- Like any other medication, desloratadine is not without its risks. You may need to be cautious taking desloratadine if you have certain health conditions such as kidney disease, liver disease, or a family history of QT syndrome.
- Pregnancy and breastfeeding always require extra care and attention. Always discuss with your healthcare provider if you?re pregnant, planning on becoming pregnant, or are nursing.
- To folks with seizure disorders or arrhythmias, particular care is needed. Desloratadine may potentially trigger seizures or worsen heart rhythms.
- Finally, conduct regular checkups when on Desloratadine to ensure the medication is working optimally and not causing undue side effects.
Interactions with Desloratadine
Common Drug Interactions
- Fluoxetine
- Erythromycin
- Ketoconazole
- Cimetidine
Alternatives to Desloratadine
- Loratadine
- Fexofenadine
- Cetirizine
- Levocetirizine
- Diphenhydramine
- Azelastine
- Olopatadine
