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Colcrys

Colcrys is a medication used primarily to treat gout attacks and prevent episodes of a condition called familial Mediterranean fever (FMF). This medication works to lessen inflammation and prevent a gout attack from worsening. Common side effects can include nausea and diarrhea.

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Frequently Asked Questions

Can Colcrys cure gout?
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No, it cannot cure gout, but it can prevent or relieve the painful attacks of gouty arthritis

Can I take Colcrys during pregnancy?
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Colcrys should be used during pregnancy only if the potential benefit justifies the risk to the fetus. Always consult your healthcare provider.

Does Colcrys interact with other medications?
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Yes, it can. Always let your healthcare provider know about all the medications you're taking.

What should I do if I miss a dose?
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If it's close to the time of your next dose, skip the missed dose and go on with your regular dosing schedule. Do not double the dose to make up for the missed one.

Comprehensive Drug Guide

How Does Colcrys Work?

Colcrys is a type of medication known as an antiinflammatory agent. It works by decreasing the buildup of uric acid crystals that cause inflammation in the affected joint(s), thereby mitigating the symptoms of a gout attack.

What is Colcrys Used For?

FDA indications: Colcrys is primarily used to prevent and treat gout attacks. It's also used to treat familial Mediterranean fever (FMF).

Offlabel uses: It's been used offlabel to treat pericarditis and Behcet's disease.

Common Dosages

Tablets: 0.6 mg

Typical Dosing

FDA Approved Indications

  • For FDAapproved indications:
  • Gout: 1.2 mg (two tablets) at the first sign of a gout attack, followed by 0.6 mg (one tablet) 1 hour later.

Off-Label Uses

  • Pericarditis: 0.50.6 mg every hour or 0.5 mg every 8 hours.
  • Behcet's disease: 0.5 1.5 mg daily.

Who Shouldn't Take Colcrys?

  • People with severe liver or kidney disease.
  • People with a blood disorder like anemia, leukopenia, or thrombocytopenia.
  • Pregnant women or women who are breastfeeding.
  • Patients taking other medications that may interact negatively with Colcrys, such as certain HIV/AIDS medications, antibiotics, antifungals, and cholesterol medications. Check with your doctor or pharmacist if you're not sure.

Advice From The Pharmacist

  • Take this medication with or without food.
  • Drink plenty of water to prevent kidney stones.
  • Notify your doctor immediately if you experience unusual bleeding or bruising, extreme tiredness, or muscle weakness.
  • Don't stop taking Colcrys suddenly unless advised by your healthcare provider.

Side Effects of Colcrys

Common Side Effects

  • Nausea, vomiting, or diarrhea.
  • Less common side effects:
  • Muscle pain or weakness.
  • Unusual bruising or bleeding.
  • Signs of infection like fever, chills, sore throat.

Risks and Warnings of Colcrys

  • Colcrys can interact with a variety of medications and can lead to serious side effects, particularly when taken in excessive amounts. Always follow your healthcare provider's instructions carefully.

Interactions with Colcrys

Common Drug Interactions

  • Certain cholesterol medications like atorvastatin and fluvastatin.
  • Antibiotics like clarithromycin
  • Antiviral drugs like ritonavir
  • Antifungals like itraconazole and ketoconazole

Alternatives to Colcrys

  • Allopurinol
  • Febuxostat
  • Probenecid
  • Indomethacin