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Clarinex
Clarinex (desloratadine) is a non-sedating antihistamine used to treat symptoms of allergic rhinitis (hay fever) and chronic idiopathic urticaria (hives). It works by blocking the action of histamine, a substance in the body that causes allergic symptoms such as sneezing, itching, runny nose, and hives. Clarinex provides relief without causing drowsiness in most patients.
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Frequently Asked Questions
How long does it take for Clarinex to start working?
Clarinex generally starts to work within 1 to 3 hours after taking a dose, providing relief from allergy symptoms.
Does Clarinex cause drowsiness?
Clarinex is a non-drowsy antihistamine, but a small percentage of users may experience mild fatigue.
What should I do if I miss a dose of Clarinex?
If you miss a dose, take it as soon as you remember. If it’s close to your next scheduled dose, skip the missed dose and continue with your regular dosing schedule.
Can I take Clarinex with other allergy medications?
It is generally safe to take Clarinex with nasal sprays or eye drops for allergy symptoms, but consult your healthcare provider before combining it with other oral antihistamines.
Is Clarinex safe for long-term use?
Yes, Clarinex is generally safe for long-term use in managing chronic allergy symptoms. However, long-term users should follow up with their healthcare provider to ensure continued safety and efficacy.
Comprehensive Drug Guide
How Does Clarinex Work?
Clarinex works by selectively blocking histamine H1 receptors, preventing the binding of histamine, which is responsible for the allergic symptoms. This reduces inflammation, swelling, and itching, helping to alleviate the discomfort associated with allergic reactions.
Common Dosages
- Tablets: 5 mg
- Oral syrup: 0.5 mg/mL
- Orally disintegrating tablets: 2.5 mg, 5 mg
Typical Dosing
- For allergic rhinitis and hives: The usual dose for adults and children over 12 is 5 mg once daily, with or without food.
Typical Dosing
FDA Approved Indications
- Allergic rhinitis (seasonal and perennial)
- Chronic idiopathic urticaria (hives)
Who Shouldn't Take Clarinex?
- Known hypersensitivity to desloratadine, loratadine, or any component of the formulation.
Advice From The Pharmacist
- Clarinex can be taken with or without food.
- Orally disintegrating tablets should be allowed to dissolve on the tongue and should not be chewed or swallowed whole.
- If you have liver or kidney disease, consult your healthcare provider for appropriate dose adjustments.
Side Effects of Clarinex
Common Side Effects
- Headache
- Dry mouth
- Fatigue
- Sore throat
Uncommon/Severe Side Effects
- Severe allergic reactions (swelling, rash, difficulty breathing)
- Liver dysfunction (yellowing of the skin or eyes)
Risks and Warnings of Clarinex
- Liver Dysfunction: In rare cases, Clarinex may cause liver problems. Patients with pre-existing liver conditions should use Clarinex with caution.
- Allergic Reactions: Although rare, some individuals may experience severe allergic reactions to Clarinex. Discontinue use and seek medical attention if swelling, rash, or difficulty breathing occurs.
Interactions with Clarinex
Common Drug Interactions
- Ketoconazole and Erythromycin: These medications may increase the blood levels of desloratadine, potentially increasing the risk of side effects.
- Alcohol: Although Clarinex is non-sedating, alcohol consumption may increase the likelihood of drowsiness in some individuals.
Alternatives to Clarinex
- Allegra (fexofenadine): Another non-drowsy antihistamine used to treat allergies and hives.
- Zyrtec (cetirizine): A second-generation antihistamine that may cause mild drowsiness in some users.
- Benadryl (diphenhydramine): A first-generation antihistamine that is more sedating but effective for short-term allergy relief.
